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mMRC dyspnea scale correlates with risk stratification and 1-year outcomes in acute pulmonary embolism patients.

mMRC dyspnea scale correlates with risk stratification and 1-year outcomes in acute pulmonary emboli…
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Key Takeaway
Note that mMRC dyspnea scale correlates with 1-year outcomes in acute pulmonary embolism patients.

This retrospective cohort study examined patients aged 18–80 years diagnosed with acute pulmonary embolism at a tertiary care center. The primary focus was the mMRC dyspnea scale as a tool for risk stratification and predicting 1-year adverse outcomes. These outcomes included in-hospital mortality, all-cause mortality after discharge, and hospital readmission. The follow-up period was 1 year.

Main results indicated that the mMRC dyspnea scale was significantly positively correlated with the risk stratification of acute pulmonary embolism. This correlation was statistically significant with a P value less than 0.05. Absolute numbers for outcomes were not reported in the available data.

Safety and tolerability data, including adverse events, serious adverse events, and discontinuations, were not reported. The study did not report a specific sample size or publication type. Limitations inherent to retrospective designs and the absence of a comparator group were not explicitly detailed in the provided text. Consequently, the certainty of the association is limited by the observational nature of the evidence.

Study Details

Study typeCohort
EvidenceLevel 3
PublishedApr 2026
View Original Abstract ↓
BackgroundThis study aimed to investigate the value of the modified Medical Research Council (mMRC) dyspnea scale in risk stratification and outcome assessment for patients with acute pulmonary embolism (APE).MethodsA retrospective analysis was performed using medical records from a tertiary care center between 2011 and 2023. The study included patients aged 18–80 years who were diagnosed with APE. Participants were categorized into groups based on pulmonary embolism risk stratification, mMRC dyspnea scale, and the presence or absence of adverse outcomes within 1 year, which included in-hospital mortality, all-cause mortality after discharge, and hospital readmission. The associations between the mMRC dyspnea scale and both APE risk stratification and 1-year adverse outcomes were evaluated. The predictive performance of the mMRC dyspnea scale for 1-year adverse prognosis was assessed using receiver operating characteristic (ROC) curve analysis to determine the optimal cut-off threshold.ResultsThe study demonstrated that the mMRC dyspnea scale was significantly positively correlated with risk stratification of APE (P 
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