5 questions answered from cited research · Plain language
Neoadjuvant chemoimmunotherapy remodels the tumor microenvironment in ESCC by increasing cytotoxic CD8+ T cells, dendritic cell remodeling, and reducing tumor volume, which correlates with better pathological response and survival.
Read the full answer →GERD increases the risk of laryngeal cancer but not esophageal squamous cell carcinoma, according to a large meta-analysis.
Read the full answer →Yes, S-1 plus radiation improves survival over radiation alone for elderly patients with inoperable esophageal squamous cell carcinoma, based on a phase III trial.
Read the full answer →Yes, deep learning models can help diagnose esophageal squamous cell carcinoma more accurately, with studies showing high AUC values for tumor detection and lymph node metastasis prediction.
Read the full answer →Adding radiation to chemotherapy before surgery does not clearly improve overall survival for esophageal squamous cell carcinoma patients compared to chemotherapy alone, but it increases the chance of a complete tumor response.
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