5 questions answered from cited research · Plain language
Genetic variants linked to fat distribution, such as those affecting subcutaneous vs. visceral fat storage, can drive insulin resistance by promoting inflammation and impairing adipose function.
Read the full answer →Yes, low-dose amiloride (5 mg daily) can reduce blood pressure and may improve insulin resistance in adults with obesity and metabolic syndrome, based on a 24-week trial.
Read the full answer →Adipose tissue macrophages (ATMs) promote obesity-related inflammation and insulin resistance by shifting to a pro-inflammatory state, driven by metabolic changes like increased glycolysis and mitophagy.
Read the full answer →Yes, exposure to microgravity changes fat distribution by increasing visceral fat and promoting inflammation, which worsens insulin resistance.
Read the full answer →Early evidence suggests acupoint catgut embedding may reduce waist circumference and improve insulin resistance in abdominal obesity, but larger, high-quality trials are needed to confirm its effectiveness.
Read the full answer →