Ultra-processed food consumption is associated with metabolic syndrome, cardiovascular risk, and allergic diseases in children
Ultra-processed foods linked to childhood weight and heart risks
This narrative review synthesizes evidence regarding the impact of ultra-processed food (UPF) on pediatric health. High UPF intake is linked…
High intake of ultra-processed foods is linked to weight gain, metabolic issues, and higher rates of asthma and skin conditions in children.
Early-life microbiome shapes allergic, metabolic, and respiratory disease risk
Gut and Lung Microbiome in Early Life Linked to Health
This narrative review synthesizes evidence on how the human gut and lung microbiome in early life influences allergic diseases, metabolic di…
A review suggests the gut and lung microbiome in early life may influence allergies, metabolism, and respiratory health.
Preoperative comorbidities linked to reduced weight loss after metabolic and bariatric surgery in adults
Pre-existing health conditions may slightly reduce weight loss after surgery
A meta-analysis of twenty-three studies reveals that mental illness, diabetes, and sleep apnea are associated with slightly lower weight los…
Adults with mental illness or diabetes before surgery saw slightly less weight loss. Other conditions like high blood pressure did not affec…
Bile acid modifications and microbiota interventions show promise for metabolic and digestive diseases in preclinical models
Bile acid and microbiota changes may help treat several diseases
This narrative review examines bile acid modifications, microbiota interventions, and BA-targeted therapies for metabolic, digestive, hepato…
This review explores how changing bile acids and gut bacteria could treat metabolic, digestive, and liver diseases, but most evidence is fro…
Mediterranean diet triples metabolic syndrome reversal rate vs low-fat diet in interim trial
Mediterranean diet reverses metabolic syndrome in 36% of patients
This interim RCT in 246 Chilean adults with metabolic syndrome found that a Mediterranean diet (with or without psychological support) led t…
A Mediterranean diet reversed metabolic syndrome in 36% of patients, compared to 11% on a low-fat diet. Early results from a Chilean trial.
Metabolic syndrome linked to higher risk of several obesity-related cancers and worse colorectal cancer survival
Metabolic Syndrome Raises Cancer Risk And Worsens Survival For Some Patients
An umbrella review of 21 systematic reviews with meta-analyses found suggestive evidence that metabolic syndrome increases the risk of sever…
A big review found that metabolic syndrome makes obesity-related cancers more likely and can hurt survival chances. Doctors say fixing this …
General obesity, central obesity, and high triglycerides increase risk of precancerous polyps in colorectal cancer surveillance
Metabolic health matters for colon cancer risk in high-risk surveillance patients
This meta-analysis of 24 observational studies found that metabolic factors such as general obesity, central obesity, hypertension, and high…
Metabolic issues like obesity and diabetes raise the risk of precancerous polyps in people at higher risk for colon cancer. This analysis of…
Narrative review links hidradenitis suppurativa to metabolic dysfunction and systemic inflammation
New review links skin disease to metabolic health in Hidradenitis suppurativa
This narrative review examines the association between hidradenitis suppurativa and metabolic syndrome. The authors argue that increasing ev…
A new review suggests Hidradenitis suppurativa is part of a broader inflammatory state tied to metabolic dysfunction, urging a multidiscipli…
Narrative review of palmitoleic acid links to metabolic health and fatty liver outcomes
Palmitoleic Acid Shows Mixed Links to Metabolic Health
This narrative review examines palmitoleic acid (POA) supplementation and food matrices regarding insulin resistance, fatty liver, and hyper…
Higher palmitoleic acid levels are tied to fatty liver and insulin resistance, but supplements show neutral effects.
Review links metabolic syndrome to 1.5 to 2 times higher atrial fibrillation risk
Metabolic syndrome raises atrial fibrillation risk by 1.5 to 2 times
This narrative review examines the association between metabolic syndrome and atrial fibrillation. The authors synthesize evidence suggestin…
Metabolic syndrome increases the risk of developing atrial fibrillation by 1.5 to 2 times, a finding that could help doctors target preventi…
Narrative review examines metabolic syndrome and novel agents in kidney transplant recipients
Kidney transplant patients face high metabolic risks and rejection
This narrative review addresses antibody-mediated rejection and metabolic syndrome in kidney transplantation recipients. The authors note th…
About half of kidney transplant recipients develop metabolic problems within a year, while antibody-mediated rejection remains a major cause…
Narrative review explores bromelain's potential across multiple chronic diseases
Bromelain shows promise for several diseases but needs more human testing
This narrative review examines bromelain's potential in cancer, cardiovascular, metabolic, infectious, and neurodegenerative diseases. Most …
Bromelain looks promising for managing cancer and other conditions, yet current evidence mostly comes from lab and animal work.
Questions about Insulin Resistance
What genetic factors linked to fat distribution cause my insulin resistance?
Genetic variants linked to fat distribution, such as those affecting subcutaneous vs. visceral fat storage, can drive insulin resistance by promoting inflammation and impairing adipose function.
Full answer →Will taking low-dose amiloride reduce my blood pressure and help insulin resistance?
Yes, low-dose amiloride (5 mg daily) can reduce blood pressure and may improve insulin resistance in adults with obesity and metabolic syndrome, based on a 24-week trial.
Full answer →How do adipose tissue macrophages affect my obesity and insulin resistance?
Adipose tissue macrophages (ATMs) promote obesity-related inflammation and insulin resistance by shifting to a pro-inflammatory state, driven by metabolic changes like increased glycolysis and mitophagy.
Full answer →Does exposure to microgravity change fat distribution and worsen my insulin resistance?
Yes, exposure to microgravity changes fat distribution by increasing visceral fat and promoting inflammation, which worsens insulin resistance.
Full answer →Can acupoint catgut embedding help treat my abdominal obesity and insulin resistance?
Early evidence suggests acupoint catgut embedding may reduce waist circumference and improve insulin resistance in abdominal obesity, but larger, high-quality trials are needed to confirm its effectiveness.
Full answer →All Insulin Resistance Articles
- Ultra-processed food consumption is associated with metabolic syndrome, cardiovascular risk, and allergic diseases in children
- Early-life microbiome shapes allergic, metabolic, and respiratory disease risk
- Preoperative comorbidities linked to reduced weight loss after metabolic and bariatric surgery in adults
- Bile acid modifications and microbiota interventions show promise for metabolic and digestive diseases in preclinical models
- Mediterranean diet triples metabolic syndrome reversal rate vs low-fat diet in interim trial
- Metabolic syndrome linked to higher risk of several obesity-related cancers and worse colorectal cancer survival
- General obesity, central obesity, and high triglycerides increase risk of precancerous polyps in colorectal cancer surveillance
- Narrative review links hidradenitis suppurativa to metabolic dysfunction and systemic inflammation
- Narrative review of palmitoleic acid links to metabolic health and fatty liver outcomes
- Review links metabolic syndrome to 1.5 to 2 times higher atrial fibrillation risk
- Narrative review examines metabolic syndrome and novel agents in kidney transplant recipients
- Narrative review explores bromelain's potential across multiple chronic diseases
- Narrative review proposes FISI tools for metabolic syndrome and diabetes management across the life cycle
- Conceptual framework review discusses metabolic autoimmune neuropsychiatric and oncological disorders without reported trial data
- Systematic review of curcumin with piperine for metabolic and cardiometabolic conditions
- Meta-analysis links moderate-to-severe obstructive sleep apnea to higher metabolic syndrome risk in patients
- Protocol for future review on acupoint catgut embedding for abdominal obesity and insulin resistance
- Umbrella review shows strong evidence for Tai Chi and aerobic exercise benefits in cardiometabolic risk factors
- Umbrella review identifies risk factors and protective factors for male infertility and semen quality
- Chiglitazar reduces liver fat in MASLD patients with hypertriglyceridemia and insulin resistance
- Systematic review finds weak link between atypical antipsychotics and MASLD in youth
- Metabolic syndrome increases chronic pancreatitis risk in UK Biobank participants
- Narrative review links ultra-processed food to obesity and multiple metabolic conditions
- VitoCheck EIT platform predicts standard diagnostics for cardiopulmonary and metabolic diseases
- Umbrella review associates processed meat consumption with higher risks of cancer and chronic disease outcomes
- GenMetS polygenic score association with cardiometabolic risk in Asian populations
- Computational model review predicts dual optima for combination therapy in ageing
- High-dose oatmeal reduces gut permeability markers in metabolic syndrome
- Narrative review links microgravity exposure to altered fat distribution and inflammation in metabolic disease models
- Narrative review supports SGLT-2i use in cardiovascular-kidney-metabolic syndrome
- Narrative review on dyslipidemia and erectile dysfunction pathophysiology
- Integrative review links sleep duration and patterns to metabolic syndrome risk
- Narrative review examines multidisciplinary strategies for metabolic syndrome in bipolar disorder
- IGFBP2 as a context-dependent regulator of metabolic dysregulation in obesity and type 2 diabetes
- Higher TyG index associated with increased hyperuricemia prevalence in metabolically healthy participants
- Narrative review discusses lipid levels in normal range regarding metabolic and endocrine disease risk
- Narrative review explores adipose tissue macrophage regulation for obesity and metabolic disorders
- Stress hyperglycemic ratio shows nonlinear link to stroke in older adults with metabolic syndrome
- Body roundness index shows significant association with metabolic syndrome but constrained predictive ability for other CKM outcomes
- Meta-analysis shows LAP levels elevated in PCOS patients with Metabolic Syndrome
- Natural and synthetic compounds suppress inflammasome activation in NLRP3-driven pathologies
- Scoping review of molecular pathways in insulin resistance among women with PCOS
- Metabolic syndrome and TyG index associated with higher in-stent restenosis risk after PCI
- Phase II RCT: Amiloride reduces arterial stiffness and blood pressure in adults with obesity and metabolic syndrome
- HIF-1α polymorphism linked to lower metabolic syndrome odds in HIV patients on ART
- Plant bioactive polysaccharides show metabolic benefits in umbrella review of systematic reviews
- Nutrition and health canteen intervention linked to weight reduction in middle-aged adults
- GWAS identifies 282 insulin resistance loci, links to fat distribution and candidate mediators
- Insulin resistance indicators TyG-BMI and METS-IR associated with pregnancy loss in recurrent pregnancy loss cohort
- Network meta-analysis ranks dietary strategies for metabolic syndrome in 1,244 patients
- Review explores gut-liver axis role in animal diseases, suggests dietary and probiotic strategies
- Psychotropic medications frequently cause metabolic adverse effects via gut-brain axis
- Network meta-analysis compares exercise types for insulin resistance in youth with overweight or obesity
- Metabolic syndrome associated with higher cardio-renal risk in kidney transplant recipients
- METS-IR shows U-shaped link to gallstone disease risk, with inflection at 29.83