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Diverse transmission dynamics and national control strategies characterize African swine fever and PRRS in AsiaNew analysis reveals how swine diseases threaten regional food security

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Key Takeaway
Note the distinct transmission drivers and varied national control strategies for ASF and PRRS in Asian swine industries.

This narrative review synthesizes the comparative epidemiology and preparedness for African swine fever (ASF) and porcine reproductive and respiratory syndrome (PRRS) within the swine industries of China, Vietnam, Thailand, and the Philippines. The scope includes an analysis of transmission characteristics, evolutionary patterns, and national control strategies in East and Southeast Asia.

The review identifies distinct drivers for both diseases: ASF is driven by environmental resistance and human-mediated routes, evolving into unpredictable endemic states with recombinant strains. In contrast, PRRS is characterized by host persistence, long-distance aerosol spread, and immune-evasive genetic diversification. National responses vary significantly, ranging from precision culling in China to archipelagic zoning in the Philippines.

Limitations include the reliance on existing literature and institutional reports rather than primary clinical trial data. The findings emphasize that regional food security requires harmonized strategies, upgraded biosecurity, and transparent surveillance aligned with World Organization for Animal Health guidelines. These insights are intended to inform regional policy and cross-border cooperation.

Keeping the food supply safe depends on understanding how diseases move through livestock. A recent review looked at African swine fever (ASF) and porcine reproductive and respiratory syndrome (PRRS). These two diseases behave very differently. ASF spreads through the environment and human activity, while PRRS spreads through long-distance air travel and the ability of the virus to hide from animal immune systems.

Different countries are using different tactics to fight these threats. China uses large scale industrial methods and precise culling. Vietnam uses certain vaccines, Thailand focuses on strict physical barriers, and the Philippines uses island zoning. Because these diseases spread across borders, experts say that sharing information and following global guidelines is vital for keeping food supplies stable.

It is important to note that this report is a summary of existing reports and literature rather than a new clinical trial. While it highlights how different regions manage these risks, the specific outcomes depend on local conditions and ongoing monitoring.

What this means for you:
Different diseases require unique regional strategies to protect livestock and ensure stable food supplies.

Common questions

How do these two pig diseases differ in how they spread?

African swine fever (ASF) is driven by environmental resistance and human-mediated routes. It has evolved from sudden outbreaks to a more unpredictable state. In contrast, porcine reproductive and respiratory syndrome (PRRS) spreads through host persistence, long-distance aerosol spread, and genetic changes that help it evade the immune system.

What different methods are countries using to control these diseases?

Countries use different tactics based on their geography. China uses mega-industrialization and precision culling. Vietnam uses partial live-attenuated vaccination. Thailand relies on strict physical biosecurity, while the Philippines uses archipelagic zoning to manage risks across its islands.

What is needed to protect the food supply from these diseases?

To ensure regional food security, experts suggest harmonized strategies, better biosecurity, and more transparent surveillance. These efforts should align with World Organization for Animal Health guidelines to help manage transboundary animal diseases effectively.

Study Details

Study typeSystematic review
EvidenceLevel 1
PublishedJul 2026
View Original Abstract ↓
East and Southeast Asia account for over half of global pork production but face unprecedented challenges from transboundary animal diseases (TADs). African swine fever (ASF) and porcine reproductive and respiratory syndrome (PRRS) are two of the most consequential diseases reshaping the region's swine industry. This narrative review summarizes literature and institutional reports from peer-reviewed scientific databases to provide a clear comparative epidemiological overview of these diseases across a strategic cross-section of four major producers: China, Vietnam, Thailand, and the Philippines. While both viruses exploit identical regional vulnerabilities, such as high-density smallholder networks, porous border trade, and farm-level containment gaps, their transmission characteristics and evolutionary patterns differ fundamentally. Driven by extreme environmental resistance, the ASF virus operates primarily via human-mediated, anthropogenic routes and has evolved from causing acute epidemics to an unpredictable endemic state marked by recombinant and gene-deleted strains. Conversely, the highly dynamic, rapidly evolving PRRS virus acts as a self-sustaining endemic engine driven by efficient host persistence, long-distance aerosol spread, and immune-evasive genetic diversification. Furthermore, national control strategies vary widely based on production infrastructure, ranging from China's mega-industrialization and precision culling to Vietnam's reliance on partial live-attenuated vaccination, Thailand's strict physical biosecurity, and the Philippines's archipelagic zoning. Together, these approaches highlight that preparedness and disease control in each country depend on harmonized strategies, upgraded biosecurity standards, knowledge sharing among the stakeholders, and transparent surveillance aligned with the World Organization for Animal Health guidelines. Importantly, cross-learning between ASF and PRRS, as well as among other TADs' frameworks, offers a pathway to more resilient not only national but also regional food security. Ultimately, advancing transboundary preparedness in the region requires coordinated, multi-country collaboration that integrates molecular surveillance networks and validated immunization protocols with practical, system-adapted execution.
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