Mode
Text Size
Log in / Sign up

Induction of Labor Reduces Shoulder Dystocia in Suspected Large-for-Gestational-Age Fetuses: Meta-AnalysisInduction of labor reduces shoulder dystocia in suspected large babies

AI-generated summary of the cited source, checked by automated accuracy review. How we work

Key Takeaway
Consider induction of labor for suspected LGA fetuses to reduce shoulder dystocia and cesarean delivery risk.

This systematic review and meta-analysis evaluated the effect of induction of labor (IOL) versus standard care in pregnant individuals at 35 weeks or later with suspected large-for-gestational-age (LGA) fetuses (defined as >90th percentile or estimated fetal weight >4000 g). The analysis included 4,083 participants and assessed outcomes including shoulder dystocia, cesarean delivery, and spontaneous vaginal delivery.

Induction of labor was associated with a significant reduction in shoulder dystocia (RR 0.68, 95% CI 0.49-0.95) and cesarean delivery (RR 0.87, 95% CI 0.79-0.96). Additionally, IOL increased the likelihood of spontaneous vaginal delivery (RR 1.12, 95% CI 1.05-1.18). The authors used the GRADE framework to assess evidence quality, though specific ratings for each outcome were not detailed.

Limitations of the review were not explicitly reported, and safety outcomes such as adverse events were not reported. The findings support reconsideration of existing clinical guidelines and may inform individualized counseling for pregnant individuals with suspected LGA fetuses. Clinicians should weigh these results alongside individual patient factors and preferences.

This systematic review and meta-analysis examined data from 4,083 pregnant individuals. The participants were at least 35 weeks pregnant with fetuses suspected to be large for gestational age. The researchers compared induction of labor against standard care. They found that induction reduced the risk of shoulder dystocia and also lowered the rate of cesarean delivery. At the same time, induction increased the likelihood of spontaneous vaginal delivery.

No adverse events or safety concerns were reported in the study. The evidence was graded using the GRADE framework to assess quality. The authors note that these findings support reconsidering existing clinical guidelines. They may also help with individualized counseling for patients and providers.

Readers should understand that this is a meta-analysis combining results from multiple studies. While the results are promising, they do not prove that induction causes these benefits in every case. The data suggests a link between induction and better outcomes for this specific group. Patients should discuss these options with their healthcare team.

What this means for you:
Induction of labor may lower shoulder dystocia and cesarean rates in suspected large babies.

Study Details

Study typeMeta analysis
EvidenceLevel 1
PublishedMay 2026
View Original Abstract ↓
BACKGROUND: Suspected large-for-gestational-age (LGA) fetuses are associated with increased risks of shoulder dystocia and adverse delivery outcomes, yet evidence on the effectiveness of induction of labor (IOL) remains inconsistent. OBJECTIVES: To evaluate whether IOL reduces shoulder dystocia and improves delivery outcomes in pregnancies with suspected LGA. METHODS: PubMed, Embase, Cochrane Library, ClinicalTrials.gov and Wanfang were searched from inception to June 30, 2025, without language restrictions. Randomized controlled trials including pregnant individuals ≥ 35 weeks with suspected LGA fetuses (>90th percentile or > 4000 g), comparing IOL with standard care, and reporting delivery outcomes. Two reviewers independently performed screening, data extraction, and risk of bias assessment. Frequentist random-effects meta-analyses, Bayesian models, and trial sequential analysis were conducted. GRADE framework was used to assess evidence quality. RESULTS: Five trials (N = 4,083) were included. IOL reduced shoulder dystocia (RR 0.68, 95% CI 0.49-0.95) and cesarean delivery (RR 0.87, 95% CI 0.79-0.96), and increased spontaneous vaginal delivery (RR 1.12, 95% CI 1.05-1.18). Trial sequential analysis indicated adequate information size. Bayesian analyses supported probable benefit, with stronger effects in per-protocol analyses. CONCLUSIONS: IOL for suspected LGA pregnancies reduces shoulder dystocia and improves delivery outcomes. These findings support reconsideration of existing clinical guidelines and may inform individualized counseling.
Free Newsletter

Clinical research that matters. Delivered to your inbox.

Join thousands of clinicians and researchers. No spam, unsubscribe anytime.