Poison center reports for kratom-containing kava products increased from 2000 to 2025

A surveillance report from the National Poison Data System (NPDS) tracked reports linked to kratom-containing kava products in the United States from 2000 to 2025. The analysis did not report the total number of cases, specific effect size, or statistical measures. It described an increase in reports over this period, but the absolute numbers and rate of increase were not provided. The report is based on passive surveillance data, which captures associations but cannot establish causation. No comparator group was defined, and the analysis did not include details on patient demographics, clinical presentations, or specific product formulations. Safety data, including adverse events, serious adverse events, and tolerability, were not reported. Key limitations include the observational nature of poison center data, which is subject to underreporting and reporting bias. The lack of detailed case information prevents assessment of clinical severity or outcomes. The report's funding sources and potential conflicts of interest were not disclosed. For practice, this report signals increased surveillance activity around these products but does not provide evidence on their specific risks or clinical impact. Clinicians should interpret the finding as a descriptive association from a public health surveillance system.