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Global DTP and measles vaccine coverage increased from 2021 to 2022 but remains below 2019 prepandemic levelsGlobal childhood vaccination rates improved in 2022 but remain below pre-pandemic levels

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Key Takeaway
Note global vaccine coverage improved in 2022 but remains below 2019 prepandemic levels.

An observational study examined global routine vaccination coverage trends. It assessed coverage with the first dose of diphtheria-tetanus-pertussis-containing vaccine (DTP1) and the first dose of measles-containing vaccine (MCV1) in the worldwide population from 2021 to 2022, comparing levels to those in 2019 before the COVID-19 pandemic.

The main results showed global DTP1 coverage increased from 86% in 2021 to 89% in 2022. Similarly, global MCV1 coverage increased from 81% in 2021 to 84% in 2022. When compared to 2019 prepandemic levels, the 2022 DTP1 coverage of 89% did not return to the 90% level seen in 2019. The 2022 MCV1 coverage of 84% also remained below the 86% coverage level from 2019.

Safety and tolerability data were not reported for this coverage analysis. Key limitations include the observational nature of the data, which reports associations and cannot establish causation. No absolute numbers of vaccinated children, effect sizes, or confidence intervals were reported, limiting precision. The findings indicate a partial recovery in global vaccination coverage from pandemic-era declines, but a persistent gap compared to prepandemic benchmarks remains a public health concern.

Researchers examined global vaccination coverage for two important childhood vaccines: the first dose of diphtheria-tetanus-pertussis (DTP) vaccine and the first dose of measles vaccine. They compared coverage rates from 2021 and 2022 to the levels seen in 2019, before the COVID-19 pandemic began. The study used worldwide data, but the exact number of children included was not reported.

The main finding was that global vaccination coverage improved from 2021 to 2022. For the DTP vaccine, coverage rose from 86% to 89%. For the measles vaccine, it increased from 81% to 84%. However, for both vaccines, the 2022 coverage rate was still lower than it was in 2019. Before the pandemic, DTP coverage was 90% and measles coverage was 86%.

This study did not report on any safety concerns related to the vaccines themselves. The main reason to be careful with these results is that this is observational data. It simply tracks what happened; it does not prove what caused the changes in vaccination rates. The data also did not include important details like exact numbers of children or statistical confidence intervals.

Readers should realistically take away that while there was a positive trend in global vaccination coverage in 2022, recovery from the pandemic's disruption is not yet complete. The data shows progress but also highlights that more work is needed to get back to pre-pandemic protection levels for children worldwide.

What this means for you:
Global childhood vaccination rates rose in 2022 but have not fully recovered to pre-pandemic levels, suggesting ongoing challenges.

Study Details

EvidenceLevel 5
PublishedOct 2023
View Original Abstract ↓
From 2021 to 2022, global coverage with the first dose of diphtheria-tetanus-pertussis-containing vaccine increased from 86% to 89%, and with the first dose of measles-containing vaccine from 81% to 84%, but neither returned to 2019 prepandemic coverage levels of 90% and 86%, respectively.
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