Mode
Text Size
Log in / Sign up

ESKD Patients Had Higher ED Hospitalization, Mortality During COVID-19 Pandemic in South KoreaDid the pandemic make emergency visits and deaths worse for adults with end-stage kidney disease?

AI-generated summary of the cited source, checked by automated accuracy review. How we work

Key Takeaway
Note: ESKD patients had higher adjusted odds of ED hospitalization and mortality during the pandemic in this observational study.

This retrospective cohort study analyzed 159,456 emergency department visits by adult patients with end-stage kidney disease (ESKD) in South Korea, using data from the National Emergency Department Information System (NEDIS). It compared the COVID-19 pandemic period (2020-2021; 83,179 visits) to a pre-pandemic period (2018-2019; 76,277 visits) to assess changes in ED utilization patterns and clinical outcomes.

The main results showed that during the pandemic, ESKD patients had higher adjusted odds of hospitalization (aOR 1.054; 95% CI 1.031–1.079) and short-term mortality (aOR 1.052; 95% CI 1.007–1.099) compared to the pre-pandemic period. The total number of ED visits also increased. The study also noted an improvement in the distribution of patients across hospital service levels during the outbreak, though specific metrics were not reported. Safety and tolerability data were not reported.

Key limitations include the observational design, which cannot establish causality, and the lack of reported absolute numbers for hospitalization and mortality rates. The findings are specific to the South Korean healthcare context during the studied pandemic years. The authors suggest the results can inform preparedness strategies for future public health emergencies, but clinicians should interpret the associations cautiously as they may reflect broader systemic strain rather than direct effects of COVID-19 infection.

Imagine having a serious kidney condition and needing urgent help. Now imagine that help becomes harder to get or less effective during a global crisis. A large review of emergency records in South Korea looked at exactly this situation for adults with end-stage kidney disease. They compared emergency visits and health outcomes during the pandemic years of 2020 and 2021 against the two years before, from 2018 to 2019. The data came from over 159,000 emergency department visits recorded in a national system.

The numbers tell a worrying story. During the pandemic, these patients were more likely to be hospitalized and more likely to die in the short term than they were before the outbreak. The risk of hospitalization rose slightly, and the risk of death also increased. At the same time, the frequency of emergency visits went up, suggesting people were seeking urgent care more often or that their conditions were worsening faster.

There was one bright spot: the distribution of patients across different hospital service levels improved during the outbreak. However, the increase in hospitalizations and deaths is a serious signal that the pandemic created extra danger for this specific group. This study does not prove the virus caused every single bad outcome, but it shows that the crisis period was linked to worse results for people with kidney failure. These findings can help doctors and leaders prepare better strategies for the next public health emergency.

What this means for you:
During the pandemic, adults with end-stage kidney disease faced higher risks of hospitalization, death, and more frequent emergency visits.

Study Details

Study typeCohort
EvidenceLevel 3
PublishedApr 2026
View Original Abstract ↓
Patients with end-stage kidney disease (ESKD) are particularly vulnerable to adverse outcomes from coronavirus disease 2019 (COVID-19). We aimed to compare emergency department (ED) utilization patterns and clinical outcomes among patients with ESKD before and during the COVID-19 pandemic to inform future healthcare planning. We analyzed data from the National Emergency Department Information System (NEDIS), a nationwide database of ED visits in South Korea. Adult patients with ESKD who visited the ED between January 1, 2018, and May 31, 2021, were included. ED visits were categorized into pre- COVID-19 (2018-2019) and COVID-19 (2020-2021) periods based on visit date. Trends in ED visit frequency, presenting causes, clinical severity, hospitalization, and short-term mortality were compared using descriptive statistics and multi-variate logistic regression. A total of 159,456 ED visits were analyzed (76,277 in 2018-2019; 83,179 in 2020-2021). Compared with the pre-pandemic period, ED visits during the COVID-19 period increased and were associated with higher odds of hospitalization [adjusted odds ratio (aOR), 1.054; 95% confidence interval (CI), 1.031–1.079] and mortality (aOR, 1.052; 95% CI, 1.007–1.099). This trend was most notable among patients presenting with severe conditions. Vascular access complications were the leading cause of ED visits during the COVID-19 period. Patients with severe illness were more likely to visit high-level hospitals and had higher rates of hospitalization and in-hospital mortality during the pandemic. The study found that patients with ESKD experienced an increase in ED visits during the COVID-19 pandemic, along with a higher risk of hospitalization and mortality; however, the distribution of patients across hospital service levels improved during the outbreak. These findings can inform preparedness strategies for future public health emergencies.
Free Newsletter

Clinical research that matters. Delivered to your inbox.

Join thousands of clinicians and researchers. No spam, unsubscribe anytime.