Mode
Text Size
Log in / Sign up
Dr. Ji-eun Park, MD
Medical Editor

Dr. Ji-eun Park, MD

Brain, Mind & Pain — CNS substrate, scale-based endpoints, neuroimaging, rehab outcomes.

Dr. Ji-eun Park is a freelance medical writer and licensed physician based in Seoul, South Korea, with over 7+ years of experience specializing in Brain, Mind & Pain. She earned her MD from Seoul National University College of Medicine and completed additional certification in Digital Health at KAIST, along with training in neuroclinical assessment and pain research methodologies.

Ji-eun focuses on neurology, psychiatry, anesthesiology, pain medicine, and rehabilitation research, with expertise in scale-based clinical endpoints, neuroimaging interpretation support, and functional recovery outcomes. She has contributed to clinical programs involving CNS disorders, chronic pain conditions, and rehabilitation-focused intervention studies.

She began her career as a practicing physician in a tertiary hospital before transitioning into medical communications, where she supported neuroscience-focused clinical programs and digital therapeutics initiatives. She brings strong clinical insight and an ability to translate complex neurobehavioral data into accessible scientific narratives.

Articles in this group — last 14 days

Comprehensive dementia care interventions improve caregiver self-efficacy in those with lower baseline scores
Physical Medicine & Rehab RCT
Comprehensive dementia care interventions improve caregiver self-efficacy in those with lower baseline scores Comprehensive Care Programs May Improve Confidence for Dementia Caregivers
This secondary analysis of a randomized pragmatic clinical trial involved 2037 caregivers of community-dwelling persons living with dementia…
Caregivers of people with dementia can improve their self-efficacy and confidence through comprehensive care programs.
Intradialytic exercise improves cardiovascular function and arterial stiffness in patients on maintenance haemodialysis
Physical Medicine & Rehab Meta-analysis
Intradialytic exercise improves cardiovascular function and arterial stiffness in patients on maintenance haemodialysis Intradialytic Exercise May Improve Heart Function in Dialysis Patients
This meta-analysis of 934 patients receiving maintenance haemodialysis found that intradialytic exercise improved left ventricular ejection …
Exercise during dialysis may improve heart function and blood pressure for patients with heart failure on maintenance hemodialysis.
Working memory training shows limited transfer between updating and span tasks
Physical Medicine & Rehab Meta-analysis
Working memory training shows limited transfer between updating and span tasks Specific memory training helps with complex mental tasks
A meta-analysis of 55 studies finds updating training transfers to span tasks, but span training does not transfer back to updating.
Not all memory exercises are equal. New data shows that training your brain to update information helps with complex tasks, but other method…
Fractional laser therapy improves scar scores and collagen regeneration more than microneedling for dermal lesions
Physical Medicine & Rehab Meta-analysis
Fractional laser therapy improves scar scores and collagen regeneration more than microneedling for dermal lesions Fractional laser therapy improves scar appearance more than microneedling
This meta-analysis compared fractional laser therapy to microneedling for non-acne scars and dermal fibrotic lesions. The analysis found a s…
Fractional laser therapy shows better results for scar severity and collagen growth than microneedling for various types of skin scars.
Organizational factors such as institutional integration and peer infrastructure influence Collegiate Recovery Program sustainability
Physical Medicine & Rehab Sys. Review
Organizational factors such as institutional integration and peer infrastructure influence Collegiate Recovery Program sustainability Factors Influencing the Sustainability of College Recovery Programs
This narrative review of 71 peer reviewed studies examines organizational factors impacting the long term sustainability of Collegiate Recov…
New research identifies key organizational factors, such as funding and peer support, that help keep recovery programs for substance use act…
School-based physical activity policies often face implementation inequities and barriers in disadvantaged populations
Physical Medicine & Rehab Sys. Review
School-based physical activity policies often face implementation inequities and barriers in disadvantaged populations School Physical Activity Policies May Not Reach All Students Equally
This narrative review examines school-based physical activity policies and implementation equity for adolescents. The authors find that part…
Students from disadvantaged backgrounds may face more barriers to physical activity due to unequal support and resources in school programs.
Local Hypothermia Shows Neurological Improvement in 54.4% of Acute Spinal Cord Injury Patients
Physical Medicine & Rehab Meta-analysis
Local Hypothermia Shows Neurological Improvement in 54.4% of Acute Spinal Cord Injury Patients Local hypothermia may help patients with acute spinal cord injuries
This meta-analysis examined local hypothermia as a neuroprotective strategy in acute spinal cord injury. Pooled data from 48 patients showed…
A review of patient data suggests that cooling the body quickly after a spinal cord injury may help some patients improve their neurological…
Moderate-intensity isotonic exercise improves function by MD -16.66 in patients with knee osteoarthritis
Physical Medicine & Rehab Meta-analysis
Moderate-intensity isotonic exercise improves function by MD -16.66 in patients with knee osteoarthritis Specific exercise volume and intensity may help manage knee osteoarthritis pain
This meta-analysis of 791 people with knee osteoarthritis found that moderate-intensity isotonic lower extremity resistance exercise signifi…
New research suggests that specific types of resistance exercises can help people with knee osteoarthritis manage pain and improve daily mov…
Structured physical exercise programs significantly reduce PTSD symptom severity in patients with post-traumatic stress disorder
Physical Medicine & Rehab Meta-analysis
Structured physical exercise programs significantly reduce PTSD symptom severity in patients with post-traumatic stress disorder Structured Physical Exercise Programs Help Reduce Symptoms for People with PTSD
This meta-analysis of randomized controlled trials involving 663 participants found that structured physical exercise programs significantly…
New research shows that regular, structured exercise can significantly lower the severity of symptoms for people living with PTSD.
Multidisciplinary interventions provide greatest clinical recovery improvements for patients with sport-related concussion
Physical Medicine & Rehab Sys. Review
Multidisciplinary interventions provide greatest clinical recovery improvements for patients with sport-related concussion Multidisciplinary Interventions Show Best Results for Concussion Recovery
This systematic review and network meta-analysis of 1320 participants evaluates various exercise-based and multidisciplinary therapies for s…
Multidisciplinary programs and combined vestibular and aerobic exercises show the strongest results for recovery after a sports-related conc…
Combined training improves HbA1c and glucose in middle-aged and older adults
Physical Medicine & Rehab Meta-analysis
Combined training improves HbA1c and glucose in middle-aged and older adults Combined aerobic and resistance training improves blood sugar levels
This meta-analysis of 1853 middle-aged and older adults found that combined aerobic and resistance training significantly improved HbA1c, HO…
Combining aerobic and resistance exercises can improve blood sugar and insulin levels in middle-aged and older adults with concerns about gl…
Blood flow restriction training improves explosive power in athletes across pooled trials
Physical Medicine & Rehab Meta-analysis
Blood flow restriction training improves explosive power in athletes across pooled trials Blood Flow Restriction Training Improves Explosive Power in Athletes
This meta-analysis of 362 competitive athletes found that blood flow restriction training (BFRT) produced small-to-moderate improvements in …
Blood flow restriction training shows promise for improving explosive power, vertical jumps, and sprint speeds in competitive athletes.
Low vision rehabilitation with optical devices improves visual outcomes and quality of life in Sub-Saharan Africa
Physical Medicine & Rehab Meta-analysis
Low vision rehabilitation with optical devices improves visual outcomes and quality of life in Sub-Saharan Africa Optical devices improve vision and quality of life in Africa
This systematic review examines the impact of low vision rehabilitation using optical devices for patients in Sub-Saharan Africa. The synthe…
Specialized optical devices help people with low vision in Sub-Saharan Africa see better, read faster, and improve their daily social lives.
The IHCHE framework provides a standardized roadmap for assessing housing quality and tenure security
Physical Medicine & Rehab Sys. Review
The IHCHE framework provides a standardized roadmap for assessing housing quality and tenure security New Framework Identifies Three Key Dimensions of Housing Accessibility
This hybrid narrative review synthesizes 280 unique records to evaluate housing conditions including physical quality, tenure security, and …
A new framework identifies how physical quality, tenure security, and structural accessibility work together to impact housing for people wi…
Impact of Very Early Exercise Rehabilitation on Functional Outcomes in Intracerebral Hemorrhage
Physical Medicine & Rehab Meta-analysis
Impact of Very Early Exercise Rehabilitation on Functional Outcomes in Intracerebral Hemorrhage Very early exercise improves recovery for brain bleed patients
Meta-analysis suggests very early exercise rehabilitation improves NIHSS and Fugl-Meyer scores in stable intracerebral hemorrhage patients.
Starting exercise rehabilitation very early after a brain bleed may lead to better physical function and movement for patients.
Cesarean delivery is associated with lower risk of postpartum stress urinary incontinence compared to vaginal delivery
Physical Medicine & Rehab Meta-analysis
Cesarean delivery is associated with lower risk of postpartum stress urinary incontinence compared to vaginal delivery Cesarean Section Delivery Linked to Lower Risk of Urinary Incontinence
This meta-analysis of observational studies evaluates pelvic floor muscle strength and anatomical parameters in postpartum women following c…
New analysis suggests that elective cesarean sections may be linked to a lower risk of urinary incontinence compared to vaginal deliveries.
Explainable machine learning may improve risk prediction and clinical decision-making for women with FGS and HIV
Psychiatry Sys. Review
Explainable machine learning may improve risk prediction and clinical decision-making for women with FGS and HIV Machine learning could help predict treatment outcomes for women with FGS
This narrative review explores the application of explainable machine learning (ML) to manage female genital schistosomiasis (FGS) and HIV c…
New machine learning models may help doctors predict treatment success and reinfection risks for women living with both FGS and HIV.
Climate-informed surveillance-to-action models address policy gaps in Somali infectious disease management
Neurology Sys. Review
Climate-informed surveillance-to-action models address policy gaps in Somali infectious disease management Climate-Informed Models Could Improve Disease Tracking in Somalia
This narrative review evaluates existing surveillance assets and policy gaps for infectious diseases in Somalia. It identifies a need for be…
A new framework aims to better connect climate warning signals to local health actions to prevent outbreaks of diseases like cholera and mal…
Tenecteplase and alteplase improve functional outcomes in extended windows but increase symptomatic intracranial hemorrhage risk
Neurology Meta-analysis
Tenecteplase and alteplase improve functional outcomes in extended windows but increase symptomatic intracranial hemorrhage risk Tenecteplase Shows Potential Benefits for Late Acute Ischemic Stroke
This meta-analysis of 4,944 patients evaluated intravenous thrombolysis with alteplase or tenecteplase between 4.5 and 24 hours after stroke…
Tenecteplase may offer similar benefits to alteplase for stroke patients while potentially carrying a lower risk of brain bleeding.
Meta-analysis Evaluating the Correlation Between Sleep Paralysis and Clinical Anxiety Symptoms
Psychiatry Meta-analysis
Meta-analysis Evaluating the Correlation Between Sleep Paralysis and Clinical Anxiety Symptoms Sleep paralysis is linked to higher levels of anxiety
A meta-analysis of 5,568 patients reveals that sleep paralysis is significantly associated with higher anxiety scores in affected individual…
People who experience sleep paralysis often report higher anxiety scores, highlighting a strong link between sleep issues and mental health.
Adjunctive acupoint application increases clinical response rates in post-stroke sleep disorders
Neurology Meta-analysis
Adjunctive acupoint application increases clinical response rates in post-stroke sleep disorders Chinese herbal acupoint application may improve sleep after a stroke
This meta-analysis of 608 patients found that adjunctive acupoint application significantly increased trial-defined clinical response rates …
New data suggests that adding herbal acupoint treatments to care can improve sleep quality for people living with sleep disorders after a st…
Transcranial pulse stimulation improves MMSE and MoCA scores in patients with Alzheimer's disease
Neurology Meta-analysis
Transcranial pulse stimulation improves MMSE and MoCA scores in patients with Alzheimer's disease Different brain stimulation methods show specific benefits for Alzheimer's
This network meta-analysis of 1,445 patients evaluated various neuromodulation techniques for Alzheimer's disease. The analysis found that t…
New research shows that different types of brain stimulation can improve specific symptoms of Alzheimer's, from memory to daily activities.
Obstetric CVST: 8.28% maternal mortality acutely, 3.17% recurrence in follow-up cohorts
Neurology Meta-analysis
Obstetric CVST: 8.28% maternal mortality acutely, 3.17% recurrence in follow-up cohorts Anticoagulants show mixed results for pregnant women with blood clots
This meta-analysis synthesizes outcomes across two distinct obstetric cerebral venous sinus thrombosis populations: acute CVST and women wit…
New data reveals that while some pregnant women with blood clots face high risks, others with known history show good delivery outcomes.
Comparing Eight Nerve Block Combinations and Local Infiltration Analgesia for Total Knee Arthroplasty
Anesthesiology & Pain Medicine RCT
Comparing Eight Nerve Block Combinations and Local Infiltration Analgesia for Total Knee Arthroplasty Nerve Block Combination May Shorten Hospital Stays After Knee Surgery
A randomized trial evaluates whether an eight-nerve block technique reduces opioid consumption and hospital stay compared to standard LIA.
A new nerve block technique for knee replacement patients showed lower opioid use and shorter hospital stays compared to standard local inje…
Lifestyle Therapy Matches CBT for Moderate-to-Severe Depression in Australian Trial
Psychiatry RCT
Lifestyle Therapy Matches CBT for Moderate-to-Severe Depression in Australian Trial Lifestyle Therapy Shows Similar Results to CBT for Depression
A telehealth lifestyle program was non-inferior to CBT for depressive symptoms at 8 weeks, with MADRS drops of 8.55 versus 6.82 points.
A new trial shows that a lifestyle program involving diet and exercise is as effective as cognitive behavioral therapy for moderate to sever…
Detectable Microembolic Signals on TCD Linked to 2.85-Fold Higher Odds of Poor Stroke Outcome
Neurology Meta-analysis
Detectable Microembolic Signals on TCD Linked to 2.85-Fold Higher Odds of Poor Stroke Outcome Microembolic signals predict poor outcomes for stroke patients
This meta-analysis of 1,777 patients with acute ischemic stroke found that detectable microembolic signals on transcranial Doppler were asso…
Detecting specific microembolic signals during a stroke can help doctors identify patients at a higher risk for poor physical recovery.
Test anxiety affects 49.8% of medical students across various geographic regions and academic years
Psychiatry Meta-analysis
Test anxiety affects 49.8% of medical students across various geographic regions and academic years Nearly half of all medical students experience test anxiety
This meta-analysis of 13,489 medical students found a pooled prevalence of test anxiety at 49.8%. Prevalence varied by gender, academic year…
Almost half of all medical students struggle with test anxiety, with first-year students and those in certain regions facing higher rates.
Unexamined relational-proximity priors may lead to misinterpreting neurodivergent behaviors as resistance or lack of insight
Psychiatry Meta-analysis
Unexamined relational-proximity priors may lead to misinterpreting neurodivergent behaviors as resistance or lack of insight Hidden assumptions may lead to misinterpreting behaviors in autism
This conceptual analysis explores how unexamined priors regarding emotional closeness and eye contact can bias the clinical interpretation o…
Hidden social expectations can cause people to mistake neurodivergent behaviors as a lack of insight or a refusal to cooperate.
Trazodone improves sleep architecture and duration in patients with depression and sleep disorders
Psychiatry Meta-analysis
Trazodone improves sleep architecture and duration in patients with depression and sleep disorders Trazodone may improve sleep quality for people with depression
This exploratory meta-analysis of 5 RCTs and 3 single-arm studies indicates that trazodone improves total sleep time and sleep efficiency wh…
Trazodone may help people with depression get more sleep and fall asleep faster, though it can cause side effects like dizziness and sleepin…
Trastuzumab emtansine and sintilimab combination shows lesion size reduction in HER2-positive metastatic gallbladder adenocarcinoma
Neurology Sys. Review
Trastuzumab emtansine and sintilimab combination shows lesion size reduction in HER2-positive metastatic gallbladder adenocarcinoma New drug combination shows promise for certain gallbladder cancer
This case report and literature review describes a 46-year-old male with HER2-positive metastatic gallbladder adenocarcinoma treated with tr…
A new treatment combination involving trastuzumab emtansine and sintilimab helped shrink tumors in a patient with a specific type of gallbla…
Opioid flexion phenotype is a descriptive term for sustained forward flexion in fentanyl exposure
Neurology Sys. Review
Opioid flexion phenotype is a descriptive term for sustained forward flexion in fentanyl exposure Opioid Flexion Phenotype Helps Identify Potential Toxicity in Overdoses
This narrative review describes the opioid flexion phenotype in patients with fentanyl exposure. The authors clarify that this posture is a …
A specific forward-leaning posture in opioid use may signal potential toxicity and help first responders prioritize life-saving ventilation.
Attentional dysfunction serves as a candidate organizing mechanism for persistent postural-perceptual dizziness
Neurology Sys. Review
Attentional dysfunction serves as a candidate organizing mechanism for persistent postural-perceptual dizziness Attentional Issues May Be a Key Factor in Dizziness
This narrative review explores attentional dysfunction as a primary mechanism underlying persistent postural-perceptual dizziness. The autho…
New research suggests that problems with how the brain processes attention may be a central cause of persistent postural-perceptual dizzines…
Neurofeedback shows potential for motor and non-motor outcomes in idiopathic Parkinson's disease
Neurology Sys. Review
Neurofeedback shows potential for motor and non-motor outcomes in idiopathic Parkinson's disease New neurofeedback methods show potential for Parkinson's disease patients
This narrative review explores the neurophysiological feasibility and clinical effects of EEG-based, fMRI-based, and DBS-guided neurofeedbac…
New research explores how brain-training techniques like neurofeedback might help people with Parkinson's manage movement and motor symptoms…
IBS-M, IBS-D, and IBS-C patients report higher severity scores and lower quality of life
Psychiatry RCT
IBS-M, IBS-D, and IBS-C patients report higher severity scores and lower quality of life IBS Patients with Mixed Stool Patterns Face Higher Symptom Severity
This cross-sectional post hoc analysis of 483 adult IBS patients found that 70% met Rome IV criteria. Patients with IBS-M, IBS-D, and IBS-C …
Patients with mixed-type IBS may experience more severe symptoms and higher rates of anxiety and depression compared to those with other sub…
DEK emerges as neuron-specific ac4C-linked driver of neuroinflammation in Parkinson's disease
Neurology Guideline
DEK emerges as neuron-specific ac4C-linked driver of neuroinflammation in Parkinson's disease New research identifies a specific gene linked to Parkinson's disease
This multi-omics analysis with in vitro validation identifies 7 ac4C-associated risk genes in Parkinson's disease and stratifies patients in…
Researchers identified a specific gene and a potential new drug target to help manage inflammation in Parkinson's disease.
Digitally Enhanced Composite Endpoints Improve Efficiency in Multiple Sclerosis Clinical Trials
Neurology Phase III
Digitally Enhanced Composite Endpoints Improve Efficiency in Multiple Sclerosis Clinical Trials New Digital Tools May Speed Up Clinical Trials for MS
Integrating remote smartphone-based gait assessments with clinical progression events significantly reduces required sample sizes and trial …
A new digital method for tracking movement could allow researchers to reach results faster and with fewer patients in multiple sclerosis tri…
Low Dose Ticagrelor and Aspirin Reduce Early Neurological Deterioration in Ischemic Stroke
Neurology RCT
Low Dose Ticagrelor and Aspirin Reduce Early Neurological Deterioration in Ischemic Stroke Trial shows ticagrelor and aspirin may reduce neurological decline
A randomized trial suggests that low-dose ticagrelor combined with aspirin significantly reduces early neurological deterioration in high-ri…
A new clinical trial suggests that a specific combination of ticagrelor and aspirin may help prevent early neurological decline after a stro…
Fresh-frozen plasma shows no protective effect against intraventricular hemorrhage in preterm infants
Neurology RCT
Fresh-frozen plasma shows no protective effect against intraventricular hemorrhage in preterm infants Trial Shows Fresh Frozen Plasma Does Not Prevent Brain Bleeding
In a target trial emulation of 748 preterm infants (gestational age ≤34 weeks) with prolonged aPTT (≥70 s), fresh-frozen plasma transfusion …
A study of 748 preterm infants found that fresh-frozen plasma transfusions did not provide a protective effect against intraventricular hemo…
Citicoline increases likelihood of achieving minimal clinically important difference in Parkinson's disease by OR 2.06
Neurology RCT
Citicoline increases likelihood of achieving minimal clinically important difference in Parkinson's disease by OR 2.06 Trial shows citicoline may improve movement in Parkinson's disease
This randomized, double-blind, multicenter trial of 485 patients with Parkinson's disease found that citicoline (1000 mg/day intramuscular) …
A new trial suggests that adding citicoline to standard medication may improve motor function and quality of life for people with Parkinson'…
Acupuncture-based interventions improve Fugl-Meyer Assessment scores for post-stroke foot drop compared to conventional treatment
Neurology Meta-analysis
Acupuncture-based interventions improve Fugl-Meyer Assessment scores for post-stroke foot drop compared to conventional treatment Acupuncture may improve movement for patients with post-stroke foot drop
This meta-analysis of 4,596 patients found that acupuncture-based interventions, including traditional and electroacupuncture, improved Fugl…
Acupuncture combined with standard care may help stroke survivors regain movement and improve scores in foot drop recovery.
Deep learning and transfer learning techniques improve cross-variability decoding of motor imagery EEG signals
Neurology Sys. Review
Deep learning and transfer learning techniques improve cross-variability decoding of motor imagery EEG signals New Deep Learning Methods Improve Brain Signal Decoding for Movement
This systematic review synthesizes research from 2020 to 2025 regarding deep learning and transfer learning for motor imagery EEG signals. T…
New deep learning techniques like transformers and meta-learning help decode brain signals for movement, potentially moving brain-computer t…
Transcranial direct current stimulation combined with cognitive training yields largest improvements in post-stroke cognitive function
Neurology Meta-analysis
Transcranial direct current stimulation combined with cognitive training yields largest improvements in post-stroke cognitive function Brain stimulation and training help stroke survivors regain memory
This systematic review of 3,842 patients with post-stroke cognitive impairment found that transcranial direct current stimulation combined w…
New research shows that combining brain stimulation with cognitive training helps stroke survivors improve their memory and thinking skills.
Non-invasive brain stimulation shows favorable tolerability and 94.9% completion rate for post-stroke upper limb rehabilitation
Neurology Meta-analysis
Non-invasive brain stimulation shows favorable tolerability and 94.9% completion rate for post-stroke upper limb rehabilitation Brain Stimulation Shows Good Safety for Post-Stroke Arm Recovery
This systematic review and network meta-analysis of 2,640 participants evaluated non-invasive brain stimulation (NIBS) for post-stroke upper…
Brain stimulation techniques show high completion rates and favorable safety for patients recovering arm movement after a stroke.
Robot-assisted gait training improves balance, walking endurance, and spatiotemporal gait parameters in Parkinson's disease
Neurology Meta-analysis
Robot-assisted gait training improves balance, walking endurance, and spatiotemporal gait parameters in Parkinson's disease Robot-Assisted Gait Training Shows Promise for Parkinson's Mobility
This meta-analysis evaluates the efficacy of robot-assisted gait training (RAGT) compared to conventional rehabilitation and other intervent…
Robot-assisted gait training may improve balance and walking endurance for people with Parkinson's disease compared to standard rehabilitati…
Technology Assisted Interventions Improve Gait and Balance in Children with Cerebral Palsy
Neurology Meta-analysis
Technology Assisted Interventions Improve Gait and Balance in Children with Cerebral Palsy Technology Assisted Training Improves Mobility for Children with Cerebral Palsy
Meta-analysis of 1,812 children shows robot-assisted gait training and virtual reality significantly improve mobility and motor function.
New technology like robot-assisted gait training and virtual reality can improve walking, balance, and motor skills for children with cerebr…
Robotics-based interventions show stronger evidence for improving upper-limb motor function after stroke
Neurology Meta-analysis
Robotics-based interventions show stronger evidence for improving upper-limb motor function after stroke Robotics Show Strong Potential for Stroke Recovery of Arm Function
This systematic review and network meta-analysis of 1,145 stroke survivors evaluated virtual reality, robotics, and brain-computer interface…
New research suggests that robotics-based therapies may offer significant improvements for stroke survivors regaining movement in their arms…
Unified Protocol for Adolescents shows significant treatment effects for hyperactivity and conduct problems
Psychiatry RCT
Unified Protocol for Adolescents shows significant treatment effects for hyperactivity and conduct problems Two School Programs Help Teens' Depression and Anxiety Equally
This randomized controlled trial of 676 adolescents with subthreshold anxiety and depressive symptoms found that the Unified Protocol for Ad…
A 676-teen trial found two group programs worked equally well for depression and anxiety, with one slightly ahead on some behaviors.
Meta-analysis finds no atypical reliance on priors in schizophrenia-spectrum psychosis
Psychiatry Meta-analysis
Meta-analysis finds no atypical reliance on priors in schizophrenia-spectrum psychosis New findings clarify how the brain processes information in people with schizophrenia
This meta-analysis of behavioral measures found no evidence for atypical reliance on priors in adults with schizophrenia-spectrum psychosis …
Researchers looked at how people with schizophrenia process information. They found no evidence for a general flaw in how the brain predicts…
Lumateperone adjunct therapy improves sexual functioning in patients with major depressive disorder
Psychiatry RCT
Lumateperone adjunct therapy improves sexual functioning in patients with major depressive disorder New medication helps sexual function in patients with depression
This study evaluated the impact of adding lumateperone to standard antidepressant therapy for adults with major depressive disorder who had …
A new treatment for depression may help patients regain sexual function that is often lost during standard antidepressant treatments.
Silexan shows clinically important adjusted mean value differences of over 0.2 points in MADRS
Psychiatry RCT
Silexan shows clinically important adjusted mean value differences of over 0.2 points in MADRS Lavender Oil Preparation Shows Potential for Treating Depression
This randomized, double-blind, placebo-controlled trial of 498 patients with mild or moderate major depressive disorder found silexan superi…
A clinical trial suggests that a lavender oil preparation called Silexan may help manage symptoms of mild to moderate depression.
Platelet-rich plasma shows potential for tissue repair and functional recovery in various nerve injuries
Psychiatry Sys. Review
Platelet-rich plasma shows potential for tissue repair and functional recovery in various nerve injuries Platelet-rich plasma shows potential for nerve and brain repair
This systematic review evaluates the preclinical potential of platelet-rich plasma (PRP) for treating spinal cord, sciatic, and facial nerve…
Platelet-rich plasma may help repair nerve damage and improve brain function in early studies, though more human testing is needed to ensure…
DORAs show strongest evidence for insomnia while sedating antidepressants vary in antidepressant activity and side effects
Psychiatry Sys. Review
DORAs show strongest evidence for insomnia while sedating antidepressants vary in antidepressant activity and side effects Sedating Antidepressants and DORAs Show Different Benefits for Depression and Insomnia
This narrative review examines sedating antidepressants and dual orexin receptor antagonists (DORAs) for patients with major depressive diso…
New research highlights how different sedating antidepressants and DORAs offer varying levels of support for patients with depression and in…
mHealth app-supported care pathway did not significantly reduce caregiver state anxiety in ENT surgery cases
Psychiatry RCT
mHealth app-supported care pathway did not significantly reduce caregiver state anxiety in ENT surgery cases Mobile app support shows mixed results for anxious surgery caregivers
This randomized controlled trial of 227 caregivers of children undergoing ENT surgery found no statistically significant difference in careg…
A new trial looks at whether a mobile app can lower anxiety for parents whose children are facing upcoming ear, nose, or throat surgeries.
Higher baseline PANSS negative symptom severity associated with lower risk of symptom exacerbation
Psychiatry RCT
Higher baseline PANSS negative symptom severity associated with lower risk of symptom exacerbation Higher Baseline Negative Symptoms Linked to More Stable Schizophrenia Course
This RCT of 1139 adults with schizophrenia found that patients in the medium and high baseline PANSS negative symptom tertiles had a lower r…
People with schizophrenia who have more severe negative symptoms at the start of treatment may experience fewer sudden flare-ups over 18 mon…
Identified barriers and enablers provide evidence based insights for scalable health system transformation strategies
Psychiatry Sys. Review
Identified barriers and enablers provide evidence based insights for scalable health system transformation strategies Health system reform: 34 barriers and 27 enablers identified
This systematic review and mixed-methods study identifies 34 barriers and 27 enablers across 6 key areas for health system transformation. T…
A new review pinpoints 34 barriers and 27 enablers that can make or break health system reforms, offering a roadmap for policymakers.
Recurrent implantation failure worsens quality of life and raises depression, anxiety in IVF patients
Psychiatry Meta-analysis
Recurrent implantation failure worsens quality of life and raises depression, anxiety in IVF patients Recurrent Implantation Failure Linked to Higher Anxiety and Depression
This meta-analysis of 28 studies in couples undergoing ICSI/IVF found that recurrent implantation failure (RIF) is associated with worse qua…
Couples facing repeated pregnancy failures during IVF may experience higher levels of anxiety, depression, and lower quality of life.
Play interventions significantly reduce anxiety and depressive symptoms in children with cancer
Psychiatry Meta-analysis
Play interventions significantly reduce anxiety and depressive symptoms in children with cancer Play Interventions Reduce Anxiety and Depression in Children with Cancer
This meta-analysis of 23 studies involving 1541 children with cancer found that play interventions significantly alleviated anxiety (SMD = -…
Play activities like medical play and group play can significantly lower anxiety and depressive symptoms in children undergoing cancer treat…
TLE4, HLA-V/HLA-G, and LRRK2 variants show significant association with Parkinson's disease in East Asian cohorts
Neurology Meta-analysis
TLE4, HLA-V/HLA-G, and LRRK2 variants show significant association with Parkinson's disease in East Asian cohorts Genetic Variants Linked to Parkinson's Disease in East Asian Populations
This meta-analysis of genetic variants in East Asian individuals identifies TLE4, HLA-V/HLA-G, and LRRK2 as significant risk factors for Par…
New research identifies specific genetic variants linked to Parkinson's disease in East Asian populations, highlighting how ancestry affects…
Martius flap, graciloplasty, and delayed coloanal anastomosis are established but evidence-limited options for rectovaginal fistula
Neurology Meta-analysis
Martius flap, graciloplasty, and delayed coloanal anastomosis are established but evidence-limited options for rectovaginal fistula Newer surgical options for radiation-induced rectovaginal fistulas
This narrative review synthesizes surgical and experimental management for radiation-induced rectovaginal fistula. The authors conclude that…
Doctors are looking at different surgical techniques to treat rectovaginal fistulas caused by radiation, though evidence for many methods re…
ILC3-to-ILC1 transition is strongly supported in Crohn's Disease but evidence for UC plasticity is limited
Neurology Sys. Review
ILC3-to-ILC1 transition is strongly supported in Crohn's Disease but evidence for UC plasticity is limited Immune Cell Changes May Offer New Paths for Crohn's Disease
This narrative review explores the role of innate lymphoid cell (ILC) plasticity in Crohn's disease and ulcerative colitis. The authors find…
New research explores how specific immune cells change in Crohn's disease, potentially leading to more precise treatments for inflammatory b…