Medical Reviewer
Dr. Ji-eun Park, MD
Brain, Mind & Pain — CNS substrate, scale-based endpoints, neuroimaging, rehab outcomes.
Dr. Ji-eun Park is a freelance medical writer and licensed physician based in Seoul, South Korea, with over 7+ years of experience specializing in Brain, Mind & Pain. She earned her MD from Seoul National University College of Medicine and completed additional certification in Digital Health at KAIST, along with training in neuroclinical assessment and pain research methodologies.
Ji-eun focuses on neurology, psychiatry, anesthesiology, pain medicine, and rehabilitation research, with expertise in scale-based clinical endpoints, neuroimaging interpretation support, and functional recovery outcomes. She has contributed to clinical programs involving CNS disorders, chronic pain conditions, and rehabilitation-focused intervention studies.
She began her career as a practicing physician in a tertiary hospital before transitioning into medical communications, where she supported neuroscience-focused clinical programs and digital therapeutics initiatives. She brings strong clinical insight and an ability to translate complex neurobehavioral data into accessible scientific narratives.
Articles in this group — last 14 days
Text-message CBT treatment reduced generalized anxiety disorder symptoms in young adults compared to wait-list control.
Text Message Therapy Reduces Anxiety Symptoms in Young Adults
This randomized clinical trial enrolled 103 young adults with generalized anxiety disorder or major depressive disorder. Participants receiv…
A text message treatment for depression also significantly lowered anxiety symptoms in young adults compared to waiting for care.
Cariprazine showed modest weight reduction versus aripiprazole in schizophrenia patients previously treated with olanzapine.
Cariprazine shows modest weight benefit over aripiprazole in schizophrenia patients
This trial compared cariprazine to aripiprazole in patients with schizophrenia who had previously used olanzapine. While both groups improve…
A trial found cariprazine linked to slightly more weight loss than aripiprazole in people with schizophrenia, though overall differences wer…
Self-help mindfulness and CBT interventions reduce depression and anxiety in distressed students
Mindfulness Apps Help Students Reduce Depression and Anxiety Symptoms
This RCT in 335 distressed university students in China found that self-help mindfulness interventions, with or without CBT, significantly r…
A trial found that online mindfulness programs significantly reduced depression and anxiety symptoms in stressed university students compare…
Values affirmation writing reduced anxiety in first-year minoritized STEM students compared to neutral writing in an RCT.
Writing Exercise Eases Anxiety in Minority STEM Students
This randomized controlled trial enrolled 69 first-year students from minoritized racial and ethnic backgrounds in STEM fields. Participants…
A brief writing exercise helped reduce anxiety and boost belonging among first-year STEM students from minoritized backgrounds.
Digital mental health intervention reduces anxiety and depression in Chinese high school students
A 12-week digital program reduced depression and anxiety in Chinese high school students
This 12-week randomized controlled trial in 390 Chinese high school students found that a digital mental health literacy intervention integr…
A 12-week digital program reduced depression and anxiety in Chinese high school students compared to controls, offering a scalable solution …
School-based screening and intervention reduced parent-reported anxiety in children aged eight to nine years
School screening program reduced child anxiety problems after one year
This cluster-randomised trial evaluated a screening-to-intervention pathway for child anxiety in primary schools in England. The study found…
A school-based screening and support program helped more children in England become free of anxiety problems after one year compared to usua…
Magnetic seizure therapy non-inferior to ECT for depression with better memory outcomes
Magnetic therapy matches standard shock therapy for depression but spares memory
This randomized non-inferiority trial compared magnetic seizure therapy (MST) with right unilateral ultra-brief ECT in 239 adults with major…
A new trial shows magnetic seizure therapy works as well as standard shock therapy for depression while causing far less memory loss in adul…
GLP-1RAs reduce weight and HbA1c in severe mental illness with low discontinuation rates
New drugs help people with severe mental illness lose weight safely
This systematic review and meta-analysis evaluated glucagon-like peptide-1 receptor agonists in individuals with severe mental illness who h…
New weight loss drugs work well and stay safe for people with severe mental illness who struggle with obesity and high blood sugar.
Meta-analysis finds decreased GDNF levels in bipolar disorder but high heterogeneity limits conclusions
Brain chemical levels differ in bipolar disorder compared to healthy people
This meta-analysis of 825 patients with bipolar disorder (BD) and 885 healthy controls found significantly lower circulating GDNF levels in …
A large review found lower levels of a specific brain chemical in people with bipolar disorder. This difference was clear even when comparin…
Meta-analysis finds NLRP3 inflammasome components upregulated in animal depression models
New research links brain inflammation to depression symptoms in animals
This systematic review and meta-analysis of 170 animals (85 depression model, 85 controls) found that protein and mRNA levels of NLRP3, ASC,…
Scientists found that specific inflammation markers rise in the brains of animals with depression, pointing to a new target for future treat…
Systematic review finds aerobic exercise improves executive function in adults with major depressive disorder
Aerobic exercise improves thinking skills in adults with major depression
This systematic review and three-level meta-analysis evaluated aerobic exercise in adults with major depressive disorder. The analysis inclu…
Adults with major depression who exercised regularly showed better focus and mental flexibility. This review found clear benefits for core t…
Systematic review finds cannabinoids reduce agitation in severe dementia but increase sedation risk
Cannabinoids Calm Agitation But Not All Dementia Symptoms
This systematic review and meta-analysis evaluated cannabinoids for neuropsychiatric symptoms in persons with dementia. The analysis include…
Cannabinoids may calm agitation in dementia patients but do not fix all behavioral problems and can make people sleepy.
Clozapine Use Linked to Higher SARS-CoV-2 Infection Risk in Severe Mental Disorders
Clozapine users faced higher risk of severe COVID-19 in large study
A meta-analysis of 155,945 outpatients with severe mental disorders found that clozapine users had a higher rate of SARS-CoV-2 infection com…
A massive analysis of over 155,000 people found that those taking clozapine had higher rates of infection and worse outcomes from COVID-19.
Preoperative psychological factors are associated with postoperative cognitive outcomes in older adults.
Psychological factors linked to cognitive issues after surgery in older adults
This systematic review and meta-analysis examined preoperative psychological factors in older adults aged 60 years or older. The analysis in…
A large review links preoperative anxiety and stress to worse cognitive outcomes after surgery for older patients.
Meta-analysis identifies moderators of the bidirectional anxiety-alcohol relationship
Age and peer influence link anxiety and alcohol use
This meta-analysis of 55 longitudinal studies examined mediators and moderators in the anxiety-alcohol pathway. Age, externalizing factors, …
Age, peer drinking, and family experiences shape how anxiety and alcohol use are linked, a review of 55 studies finds.
Meta-analysis reviews psychosis prevalence in bipolar disorder patients across 285 studies
Psychosis common in bipolar disorder, review finds
This meta-analysis reviews data from 285 studies regarding the prevalence of psychosis and psychotic symptoms in patients with bipolar disor…
Nearly half of people with bipolar disorder experience psychosis, and 8% also have schizophrenia, a review of 285 studies finds.
Systematic review and meta-analysis of digital technology interventions for cognitive function and mood in older adults
Digital tools may boost brain health in older adults
This systematic review and meta-analysis evaluated digital technology interventions in older adults with cognitive impairment, depression, a…
Using digital technology like apps or online programs may improve thinking skills and mood in older adults, a new analysis suggests.
Meta-analysis finds VR distraction does not reduce pain during IUD insertion but may lower anxiety
Virtual reality fails to stop pain during IUD insertion but helps with anxiety
This systematic review and meta-analysis of 4 RCTs (n=440) found that immersive virtual reality distraction did not significantly reduce pos…
New research shows virtual reality helps women feel less anxious during IUD insertion but does not reduce their physical pain.
Aerobic and strength training reduce fatigue in multiple sclerosis patients
Aerobic or strength training eases MS fatigue, trial finds
This randomized effectiveness trial in 62 persons with multiple sclerosis and fatigue found that 8 weeks of aerobic training, strength train…
A small trial finds that aerobic and strength training each reduce fatigue in MS, with no clear winner among exercise types.
Modified CIMT with trunk restraint improves function in chronic stroke patients
Six weeks of tailored therapy improved function and quality of life for chronic stroke patients.
A single-blinded RCT in 34 chronic stroke patients found that adding patient-tailored modified constraint-induced movement therapy (mCIMT) w…
Thirty-four people with long-term stroke saw better movement and balance after six weeks of a specific therapy mix compared to standard care…
Laughter yoga reduced fatigue in people with multiple sclerosis in a randomized controlled trial
Laughter Yoga Cuts Fatigue And Improves Sleep For Multiple Sclerosis Patients
This randomized controlled trial enrolled 42 people with multiple sclerosis. Participants in the intervention group received 12 sessions of …
People with multiple sclerosis who practiced laughter yoga reported less tiredness and better sleep after just twelve sessions.
Exercise training improves cognition and fatigue in older adults with multiple sclerosis
Exercise boosts brain and cuts fatigue in older adults with MS
This Phase-Ib randomized controlled trial in 51 older adults with multiple sclerosis found that 16 weeks of home-based aerobic and resistanc…
A 16-week home exercise program improved thinking speed, executive function, fatigue, and quality of life in older adults with multiple scle…
Exoskeleton-assisted robotic therapy improves upper limb motor scores versus conventional rehabilitation in poststroke inpatients
Robotic Therapy Helps Stroke Patients Regain Arm Function Faster
This multicenter, single-blind randomized controlled trial enrolled 94 inpatients with moderate-to-severe upper limb impairment within three…
A trial of 94 stroke patients found robotic arm therapy led to significantly better motor recovery than standard rehabilitation within five …
Anodal tDCS combined with therapy enhanced verb naming in chronic post-stroke aphasia
Stimulation plus therapy improves word finding in chronic stroke aphasia
This double-blind, sham-controlled crossover study investigated anodal tDCS over the left inferior frontal gyrus combined with verb naming t…
A small study found that combining brain stimulation with speech therapy helped people with chronic stroke aphasia name verbs better, with b…
Action observation combined with virtual reality improves paretic hand function in poststroke adults with hemiplegia
Action observation plus virtual reality boosts hand recovery after stroke
This randomized controlled trial evaluated poststroke adults with hemiplegia in inpatient rehabilitation centers in Italy. The experimental …
Adding action observation to virtual reality training helped poststroke adults regain better hand function than virtual reality alone in thi…
Post-hoc ATTEND trial analysis shows stroke severity and caregiver factors predict 6-month outcomes in India.
Stroke recovery in India depends heavily on age and caregiver support
This post-hoc analysis of a multicentre, prospective, randomised, open blinded endpoint trial evaluated 1,250 participants with acute stroke…
A look at 1,250 stroke patients in India shows that older age and certain caregivers predict worse long-term outcomes.
Glenzocimab fails to improve outcomes in acute ischemic stroke thrombolysis
New stroke drug shows no benefit for patients treated with clot-busting therapy
This phase 2/3 randomized trial tested glenzocimab versus placebo in 421 patients with acute ischemic stroke treated by thrombolysis. The pr…
A major trial found that glenzocimab did not improve long-term disability scores for stroke patients who received standard clot-busting trea…
Systematic review and meta-analysis shows rTMS reduces post-stroke shoulder pain in stroke survivors.
Magnetic pulses ease shoulder pain for stroke survivors
This systematic review and meta-analysis evaluated repetitive transcranial magnetic stimulation (rTMS) for post-stroke shoulder pain in over…
A new analysis of over 500 stroke survivors found magnetic pulses significantly reduced shoulder pain and improved movement compared to stan…
Systematic Review and Meta-Analysis: Non-Invasive Brain Stimulation for Visual Perception After Stroke
New brain stimulation helps stroke patients see better than before
This systematic review and meta-analysis examined non-invasive brain stimulation (NIBS) for visual perception after stroke. Pooled results s…
A new review shows brain stimulation helps stroke patients see better, offering hope for those struggling with vision loss after a stroke.
Systematic review and meta-analysis of dietary restriction in Alzheimer's mouse models
Dietary restrictions show mixed results in Alzheimer's mouse models
This systematic review and meta-analysis of 23 studies examined five dietary restriction regimens in Alzheimer's disease mouse models. Calor…
A meta-analysis of 23 studies found fasting-mimicking diets had the largest effects, while intermittent fasting improved memory but worsened…
Meta-analysis shows semi-immersive VR improves hand function in post-stroke patients with over 12 hours of therapy
Virtual Reality Therapy Improves Hand Function After Stroke
This meta-analysis of randomized controlled trials evaluated virtual reality therapy for patients with hemiplegia after stroke. The pooled a…
A meta-analysis of trials shows virtual reality therapy significantly improves hand function in stroke patients, especially with longer trea…
Systematic review shows high prevalence of covert cerebrovascular changes in schizophrenia patients compared to controls
Brain scans show hidden vessel changes in many people with schizophrenia
This systematic review and meta-analysis evaluated 11,611 patients with schizophrenia and controls from international and Chinese databases.…
A large review found hidden signs of blood vessel issues in many people with schizophrenia, though experts urge caution before drawing firm …
Meta-analysis finds PLISSIT counseling improves sexual life in women with MS
Counseling helps sexual life for women with Multiple Sclerosis
This systematic review and meta-analysis of 232 women with multiple sclerosis found that counseling interventions based on the PLISSIT model…
A new review found counseling based on the PLISSIT model had a high and positive effect on the sexual lives of women with Multiple Sclerosis…
Exercise reduces blood pressure after stroke or TIA: systematic review and meta-analysis
Exercise lowers blood pressure after stroke, review finds
This systematic review and meta-analysis of 25 studies found that aerobic exercise reduces systolic blood pressure by 3.79 mmHg and diastoli…
A review of 25 studies finds aerobic and combined exercise can significantly lower blood pressure in stroke survivors.
Sleep efficiency improved with mindfulness in multiple sclerosis patients according to a meta-analysis
Mindfulness and Melatonin May Help Sleep in Multiple Sclerosis
This systematic review and meta-analysis evaluated non-pharmacologic and pharmacologic interventions for sleep in people with multiple scler…
A review of ten studies suggests mindfulness, melatonin, and other therapies may improve sleep for people with multiple sclerosis, though mo…
Meta-analysis shows reduced stress-induced autonomic responses in people with multiple sclerosis compared to controls
People with MS show reduced autonomic responses to stress compared to controls
This meta-analysis reviews fourteen studies examining autonomic responses to emotional or stress-related stimuli in people with multiple scl…
A meta-analysis of fourteen studies found that people with multiple sclerosis have lower stress-induced autonomic responses than healthy con…
Systematic review and meta-analysis of NMES for post-stroke dysphagia outcomes
NMES alone does not beat standard therapy for post-stroke swallowing problems
This systematic review and meta-analysis evaluated neuromuscular electrical stimulation (NMES) alone versus NMES combined with or compared t…
A review of sixteen studies found that adding neuromuscular electrical stimulation to standard care helps, but using it alone does not impro…
Meta-analysis shows MRI volumetric differences in Parkinson's disease with mild cognitive impairment versus cognitively normal patients
New scan signs reveal early brain changes in Parkinson's dementia risk
This systematic review and meta-analysis evaluates gray matter volume alterations across six subcortical regions in patients with Parkinson'…
A new scan pattern shows specific brain shrinkage in Parkinson's patients who are starting to forget things, helping doctors catch dementia …
Systematic review and meta-analysis finds abdominal acupuncture may improve poststroke constipation
Acupuncture plus standard care helps poststroke constipation, but evidence remains uncertain
This systematic review and meta-analysis of 943 patients evaluated abdominal acupuncture combined with conventional therapy for poststroke c…
A meta-analysis suggests acupuncture combined with standard care improves bowel movements for stroke survivors, though study limits make res…
Review of P-BANN framework for Parkinson disease proteomics data analysis
New tool helps map proteins in Parkinson disease
This methodological review synthesizes the application of the P-BANN framework, a biologically annotated neural network model, to proteomics…
A new method finds specific protein groups linked to disease pathways in Parkinson disease, offering a fresh way to study the condition.
Five-variable admission model predicts 90-day outcomes in 245 aneurysmal subarachnoid hemorrhage patients
New model predicts recovery after aneurysmal subarachnoid hemorrhage
This single-center cohort study evaluated an admission-based five-variable model in 245 consecutive treatment-eligible patients with aneurys…
A simple 5-factor model at hospital admission accurately predicts 90-day recovery after bleeding stroke.
Longitudinal study of 148 stroke patients examines cognitive and motor recovery correlations at one and three months.
After a stroke, thinking and movement recovery may be linked
This longitudinal study of 148 individuals in the subacute phase of stroke examined correlations between cognitive and motor impairment. Res…
Stroke survivors' thinking and movement improvements are linked, but early thinking skills don't predict motor recovery.
Review of pooled psilocybin data suggests broadening blood pressure eligibility criteria for psychiatric trials
Psilocybin raises blood pressure briefly but stays safe for most patients
This pooled analysis review examined blood pressure and heart rate responses in 368 participants receiving 536 psilocybin sessions at Johns …
New data shows psilocybin raises blood pressure only briefly, suggesting doctors could safely treat more patients with mild high blood press…
Chronic psychosocial stress linked to higher perivascular space volumes in healthy young adults
Stress linked to brain changes in healthy young adults
This cohort study of 61 healthy young adults found that chronic psychosocial stress was associated with significantly higher fractional peri…
Chronic stress may cause subtle brain changes in healthy young adults, a new study finds.
SBP trajectory clusters associated with acute kidney injury risk in spontaneous intracerebral hemorrhage patients
Blood Pressure Patterns Linked to Kidney Injury in Brain Bleed Patients
This retrospective cohort study examined 233 adults in the intensive care unit with spontaneous intracerebral hemorrhage. Patients were grou…
In ICU patients with brain bleeds, specific blood pressure changes were linked to higher odds of kidney injury, while other outcomes showed …
Routinely available clinical variables predict swallowing status after stroke
Routinely available variables may help estimate swallowing status after acute stroke
This retrospective observational study of 126 patients with first-ever stroke found that routinely available clinical variables can predict …
A new analysis suggests common hospital data points could help estimate swallowing ability in stroke patients when specialized tests are mis…
Kinesio Taping Plus Stretching Improves Pain and Function in Carpal Tunnel Syndrome
Home taping beats electrical stimulation for wrist pain and grip strength in adults
This randomized controlled trial in 42 adults with carpal tunnel syndrome compared home-based Kinesio taping plus myofascial stretching to T…
A home-based taping method combined with stretching improved wrist pain and grip strength more than electrical stimulation in adults with ca…
Narrative review discusses link between diamine oxidase deficiency and fibromyalgia pathophysiology
DAO supplementation may reduce fibromyalgia pain and impact
This narrative review examines the relationship between histamine intolerance, diamine oxidase (DAO) deficiency, and fibromyalgia. The autho…
New evidence suggests that addressing diamine oxidase deficiency could help reduce pain and improve daily life for some people with fibromya…
Narrative review identifies determinants of susceptibility to digital health misinformation
What makes people fall for health misinformation online?
This narrative review examines the determinants of susceptibility to digital health misinformation across individual, relational, and platfo…
Low health literacy and emotional reasoning make people more vulnerable to digital health misinformation, a new review finds.
Higher levels of dissociative symptoms observed in individuals with functional neurological disorder
People with FND experience higher levels of dissociation
This pilot study used ecological momentary assessment to compare symptoms between individuals with functional neurological disorder and heal…
New tracking data shows that individuals living with functional neurological disorder report significantly more dissociative symptoms during…
Diabetes and social support associations with cognitive impairment in elderly schizophrenia inpatients
Social support and daily living skills linked to lower dementia risk in schizophrenia
This retrospective cross-sectional study of 149 elderly inpatients with schizophrenia found a 47.7% prevalence of cognitive impairment. High…
Nearly half of elderly schizophrenia patients have cognitive impairment. Social support and daily living skills may protect against it.
CBCL-10 shows good diagnostic efficiency for ADHD in a longitudinal cohort study
Shortened checklist shows good efficiency for ADHD diagnosis
This longitudinal cohort study of 1,786 youth evaluated the measurement properties of the Child Behavior Checklist-10 (CBCL-10). The results…
A shorter version of a common behavioral checklist may help clinicians identify ADHD symptoms in children with high accuracy.
Clinical features and treatment responses in 40 male patients with VEXAS syndrome
HMA treatment shows promise for VEXAS syndrome patients
This retrospective multicenter study of 40 male patients with VEXAS syndrome evaluated clinical features and various treatment responses. Re…
New data on VEXAS syndrome suggests that hypomethylating agents may help improve clinical and biological responses in men.
Self-efficacy and age associated with disability acceptance trajectories in hypertensive intracerebral hemorrhage patients
Belief in yourself helps people accept life after brain bleeds
This prospective longitudinal study of 114 patients with hypertensive intracerebral hemorrhage examined the developmental trajectory of disa…
New research shows that your confidence in your own abilities can help you navigate the difficult journey of accepting a disability.
A prediction model for futile reperfusion after endovascular thrombectomy in large vessel occlusion stroke
New Model Predicts Futile Stroke Reperfusion After Clot Removal
This retrospective cohort study developed a model using clinical, imaging, and laboratory markers to predict futile reperfusion after endova…
A new tool combining clinical, imaging, and lab data can predict which stroke patients may not benefit from clot removal.
Peripheral nerve lesion types in patients with primary Sjögren's syndrome
Nerve damage affects many people with Sjögren's syndrome
This retrospective observational study of 92 patients with primary Sjögren's syndrome examined the clinical and serological characteristics …
New data shows that nerve issues are common in Sjögren's syndrome patients and may follow a specific pattern.
Meta-analysis shows repetitive peripheral magnetic stimulation effects on stroke motor recovery
New rules for magnetic therapy boost arm recovery after stroke
This meta-analysis of 14 trials involving 580 stroke patients evaluates the effects of repetitive peripheral magnetic stimulation (rPMS) on …
New magnetic therapy rules help stroke patients regain arm strength faster when used for the right length of time
Preconception environments linked to pregnancy-related brain remodeling and better maternal mental health in a Singaporean cohort
Preconception lifestyle choices may shape brain resilience during pregnancy
This observational cohort study of 194 preconception participants and 61 postpartum participants from Singapore examined how lifestyle and s…
A Singapore study links healthy preconception habits to better brain changes during pregnancy and lower anxiety for moms and kids.
Neuroimaging features predict ASD identification and cognitive decoding accuracy in large cohorts
New AI Model Finds Brain Pattern That Predicts Autism Symptoms
This cohort study analyzed individuals from three independent large-scale neuroimaging cohorts (HCP-task, ABIDE-I, ABIDE-II). Cognitive deco…
A new tool finds a clear brain signal that predicts autism symptoms with high accuracy.
Observational study finds higher hostility bias in genetic generalised epilepsy
People with genetic generalised epilepsy show higher hostility bias than healthy controls
This observational study compared attributional bias in 96 participants with genetic generalised epilepsy, temporal lobe epilepsy, and healt…
A new study found that people with genetic generalised epilepsy often blame others more than healthy people do, a sign of social difficulty.