Medical Editor
Dr. Ji-eun Park, MD
Brain, Mind & Pain — CNS substrate, scale-based endpoints, neuroimaging, rehab outcomes.
Dr. Ji-eun Park is a freelance medical writer and licensed physician based in Seoul, South Korea, with over 7+ years of experience specializing in Brain, Mind & Pain. She earned her MD from Seoul National University College of Medicine and completed additional certification in Digital Health at KAIST, along with training in neuroclinical assessment and pain research methodologies.
Ji-eun focuses on neurology, psychiatry, anesthesiology, pain medicine, and rehabilitation research, with expertise in scale-based clinical endpoints, neuroimaging interpretation support, and functional recovery outcomes. She has contributed to clinical programs involving CNS disorders, chronic pain conditions, and rehabilitation-focused intervention studies.
She began her career as a practicing physician in a tertiary hospital before transitioning into medical communications, where she supported neuroscience-focused clinical programs and digital therapeutics initiatives. She brings strong clinical insight and an ability to translate complex neurobehavioral data into accessible scientific narratives.
Articles in this group — last 14 days
Gut microbiota-associated signals may influence immune homeostasis and neuroinflammation in neurodegenerative diseases
Gut bacteria may influence immune health in the central nervous system
This systematic review explores how gut microbiota-associated signals, including short-chain fatty acids and bile acids, may influence immun…
Gut bacteria and their byproducts may influence immune responses and inflammation in the brain, potentially impacting several neurodegenerat…
Auditory sensory stimulation is associated with higher Glasgow Coma Scale scores in disorders of consciousness
Auditory stimulation may improve consciousness levels in patients with disorders
This meta-analysis of 713 patients with disorders of consciousness found that auditory sensory stimulation is associated with higher Glasgow…
Auditory sensory stimulation may help improve consciousness levels and lower pulse rates in patients with disorders of consciousness.
Acceptance and Commitment Therapy reduces depressive and anxiety symptoms in stroke patients
Acceptance and Commitment Therapy May Help Stroke Patients' Mood
This meta-analysis of 1,975 stroke patients found that Acceptance and Commitment Therapy (ACT) significantly reduced depressive symptoms (SM…
A review of studies suggests that Acceptance and Commitment Therapy can reduce depression and anxiety symptoms in people who have had a stro…
Sleep and circadian disturbances characterize behavioral patterns and physiology in patients with Alzheimer disease
Sleep and Circadian Disturbances Impact Patients with Alzheimer's Disease
This narrative review explores how sleep and circadian disturbances impact patients with Alzheimer disease. It synthesizes findings on behav…
Understanding how sleep patterns and internal body clocks affect those with Alzheimer's disease can help identify key areas for clinical car…
Telehealth physical therapy for low back pain in rural Maryland faces access and technology barriers, qualitative study finds
Telehealth physical therapy shows promise for rural low back pain
This guideline-related qualitative analysis identifies 10 themes affecting the feasibility of delivering guideline-based low back pain physi…
New research explores how telehealth can help rural patients manage low back pain while reducing the need for opioid medications.
Electrical stimulation improves clinical response and reduces depressive symptom severity in patients with depression
Electrical Stimulation Shows Potential for Managing Depression Symptoms
This systematic review and network meta-analysis of 2,664 patients found that electrical stimulation significantly improved clinical respons…
New analysis suggests specific types of electrical stimulation may improve clinical response and reduce symptom severity for people living w…
Minocycline reduces 3-month NIH Stroke Scale scores by 2.43 in acute ischemic stroke
Minocycline may improve recovery for some patients after ischemic stroke
This meta-analysis of 2186 patients with acute ischemic and intracerebral hemorrhage evaluated the impact of minocycline on neurological out…
A review of clinical data suggests the antibiotic minocycline could help some patients regain function after an ischemic stroke.
Resistance training raises peripheral BDNF in MS, but low-certainty evidence limits confidence
Resistance training may increase BDNF levels in people with MS
This meta-analysis of four studies (126 individuals with MS) found that isolated resistance training increased peripheral BDNF levels (SMD 0…
New data suggests that specific types of resistance training can boost a protein in the blood that supports brain health for people with MS.
Digital Medicine implementation evidence is strongest in asthma, partial in CF, and not yet systematic in COPD
Digital tools show promise for managing several lung diseases
This systematic review of reviews examined barriers, facilitators, and transferable concepts for implementing Digital Medicine in respirator…
New research identifies how digital tools can help patients manage asthma and cystic fibrosis, though more data is needed for other conditio…
Evolutionary models suggest parasite defense and hygiene factors drive allergic type 1 hypersensitivity
Evolutionary theories explain why the human body develops allergic reactions today
This narrative review synthesizes evolutionary models for allergic diseases, including parasite defense, reduced microbial exposure, and hyg…
Scientists are looking at why our bodies react to harmless things like pollen. New theories suggest our immune systems are overreacting to m…
A three-compartment framework categorizes non-atherosclerotic vasculopathies into structural, functional, and inflammatory components
New Framework Helps Doctors Identify Non-Atherosclerotic Vascular Conditions
This narrative review proposes a conceptual framework for non-atherosclerotic vasculopathies (NAV) based on structural, functional, and infl…
A new framework helps doctors categorize and treat non-atherosclerotic vasculopathies by focusing on structural, functional, and inflammator…
CGRP-targeted therapies provide clinically meaningful improvements in vertigo frequency and patient-reported quality of life
New CGRP therapies show promise for vestibular migraine relief
This systematic review evaluates the efficacy of conventional pharmacological treatments and CGRP-targeted therapies for vestibular migraine…
Newer CGRP-targeted treatments may offer significant relief for those struggling with the dizzy spells and headaches of vestibular migraine.
Combined magnetic stimulation and rTMS improve upper limb motor function and activities of daily living
Magnetic stimulation shows promise for stroke patients' arm movement
This systematic review and network meta-analysis of 48 randomized controlled trials indicates that rPMS, rTMS, and combined MS are superior …
Combining different types of magnetic stimulation may help stroke survivors regain arm movement and perform daily tasks better than standard…
Stroke coordinator-led intervention shows less favorable mRS outcomes in patients aged 80 years and older
Trial Shows Stroke Coordination Program Impacts Outcomes by Age
This randomized trial of 301 participants with mild stroke symptoms found that a coordinator-led intervention resulted in fewer favorable mR…
A new trial shows that a community-based stroke program helps younger patients with cognitive speed but may not help those over 80.
Blood flow restriction training improves lower-limb function and walking distance in post-stroke patients
Blood flow restriction training may improve walking after a stroke
This meta-analysis evaluates the impact of blood flow restriction training on lower-limb function and walking performance in adults after st…
Blood flow restriction training shows promise in helping stroke survivors improve their balance and walking distance during recovery.
Study-defined hypertension is not a statistically significant predictor of recurrence in intracranial aneurysms
High blood pressure may not predict aneurysm recurrence after treatment
This systematic review and meta-analysis of 2,442 observations from 8 studies found no statistically significant association between study-d…
New data suggests that a history of high blood pressure does not clearly predict if an aneurysm will return after surgery.
TPOAb positivity is associated with a 1.52 relative risk of perinatal depression in females
Thyroid antibodies linked to higher risk of perinatal depression
This meta-analysis of 10,559 females found that TPOAb positivity is associated with a significantly higher risk of perinatal depression (RR=…
Women with certain thyroid antibodies may face a higher risk of depression during pregnancy and the period surrounding childbirth.
EBV VCA-IgG seroprevalence of 75% correlates with rising MS prevalence in MENA regions
Link Found Between Epstein-Barr Virus and Multiple Sclerosis Cases
This meta-analysis of 131 studies examines the relationship between Epstein-Barr virus (EBV) and multiple sclerosis (MS) in the MENA region.…
A large review of data from the Middle East and North Africa shows a link between rising Epstein-Barr virus rates and Multiple Sclerosis cas…
Physical literacy programs for children with special educational needs lack consistent framework and inclusive settings
Physical Literacy Programs Support Students With Special Educational Needs
This scoping review of 22 empirical studies examines physical literacy programs for children and adolescents with special educational needs.…
New research highlights how physical literacy programs can build confidence and skill for children with special educational needs in school …
MBSR matches escitalopram for GAD anxiety, with high-certainty evidence
Mindfulness Training Shows Similar Results to Medication for Anxiety
This meta-analysis examined Mindfulness-Based Stress Reduction (MBSR) for adults with generalized anxiety disorder across waitlist, active c…
Mindfulness-based stress reduction may be as effective as certain medications for adults living with generalized anxiety disorder.
STN-SNr co-stimulation adds no motor or gait benefit over STN-only in Parkinson's
Trial shows no added benefit for specific Parkinson's brain stimulation
This meta-analysis of 10 studies (109 evaluable participants) found no between-group difference for STN-SNr co-stimulation versus STN-only s…
New analysis shows that adding a second stimulation point in the brain does not improve movement for Parkinson's patients.
Neuromelanin-sensitive MRI shows significant group-level differences in LC signal and volume in Parkinson's disease
MRI Imaging Shows Distinct Changes in Parkinson's Disease Patients
This meta-analysis of 1,078 participants with Parkinson's disease and 543 healthy controls found significantly lower LC signal (Hedges' g = …
New imaging data shows significant differences in brain signals for people with Parkinson's disease compared to healthy individuals.
Microglia and astrocyte crosstalk serves as a key mediator of central sensitization in vestibular migraine
Brain cells may drive the pain of vestibular migraines
This systematic review explores the role of neuroimmune interactions in the pathophysiology of vestibular migraine. The authors identify bid…
New research highlights how specific brain cells communicate to cause chronic pain, offering a path to better treatments for vestibular migr…
Digital neurorehabilitation improvements in virtual environments do not consistently translate to real-world functional gains
Digital Rehab Gains May Not Carry Into Daily Life
This mini review examines the transfer of gains from digital neurorehabilitation to real-world function. The authors conclude that improveme…
Skills learned in rehab games and virtual settings may not carry over into everyday function, a new review warns.
Respiratory muscle training improves respiratory function and reduces pneumonia risk in subacute stroke
Respiratory muscle training improves outcomes for patients after stroke
This meta-analysis of 11 trials indicates that respiratory muscle training improves several respiratory metrics and functional scores in pat…
Training the muscles used for breathing may help stroke survivors walk further and reduce the risk of developing pneumonia.
Amyloid and tau pathology in the biomarker-detectable range occurred in 19.6% of decedents
Study links specific brain protein patterns to Alzheimer disease progression
This cross-sectional clinicopathologic study of 2,711 decedents analyzed the relationship between amyloid and tau pathology and cognitive im…
New research shows that specific combinations of amyloid and tau proteins in the brain are linked to the progression of Alzheimer disease sy…
Obstructive sleep apnea is associated with significant impairment of glymphatic transport via DTI-ALPS index
Sleep Disorders and the Brains Waste Removal System Impact on Health
This meta-analysis examines glymphatic-related metrics in patients with obstructive sleep apnea, sleep deprivation, and narcolepsy type 1. F…
New research shows that obstructive sleep apnea may damage the brain's waste cleaning system, potentially leading to long-term brain health …
Current evidence does not establish statins or nitric oxide donors as acute cytoprotective therapies
New insights into brain protection methods for patients with acute stroke
This narrative review explores various brain cytoprotection strategies for acute ischemic stroke, including excitotoxicity, redox, and infla…
Doctors are looking at different ways to protect brain cells after a stroke. Some treatments show promise while others have not worked well.
Bacterial lysates reduce exacerbation risk and hospitalization in patients with chronic obstructive pulmonary disease
Bacterial lysates may lower hospital risk for COPD patients
This meta-analysis of randomized trials evaluates the impact of bacterial lysates on outcomes in adults with chronic obstructive pulmonary d…
New data suggests that bacterial lysates could reduce the risk of flare-ups and hospital stays for people living with COPD.
Active rTMS to the DLPFC for patients undergoing major abdominal surgery
Trial plans to use magnetic pulses for abdominal surgery recovery
This study protocol describes a planned randomized controlled trial of 208 participants undergoing major abdominal surgery. The study aims t…
A new trial plans to use noninvasive magnetic pulses to help patients manage pain and recovery after major abdominal surgery.
Evaluating Digital and In-Person Interventions for Migrant Mental Health in Italy
Trial to Test Self-Help Mental Health Support for Migrants
A randomized hybrid study evaluates in-person and online interventions to manage depressive and anxiety symptoms in adult migrants in Italy.
A new trial will test whether self-help programs can ease depression and anxiety in adult migrants resettled in Italy.
rTMS combined with sertraline improves depressive symptoms and cognitive scores in adolescents
rTMS Combined With Sertraline May Improve Adolescent Depression
This meta-analysis of 2,155 patients in China found that rTMS combined with sertraline significantly reduced HAMD-17 (SMD = -1.06) and HAMD-…
Combining rTMS with sertraline may help reduce depression symptoms and improve cognitive scores in adolescents compared to sertraline alone.
Prognostic covariate adjustment reduces required sample size by 15-28% in Huntington's Disease trials
New Modeling Improves Data Accuracy for Huntington's Disease Trials
This modeling study evaluated the impact of prognostic covariate adjustment on statistical power in Huntington's Disease trials. The analysi…
New modeling techniques could improve the accuracy of data in Huntington's disease clinical trials, helping researchers identify meaningful …
Higher GrimAge epigenetic age acceleration is significantly associated with higher dementia risk
GrimAge metric shows link to increased risk of dementia
This meta-analysis of 46,365 individuals with neurodegenerative diseases found that only the GrimAge metric showed a significant association…
One specific biological age clock, known as GrimAge, showed a link to higher dementia risk in a large study of over 46,000 people.
Transcranial magnetic stimulation modulates transcriptomic and connectomic changes in treatment-resistant depression
Magnetic brain stimulation may change how cells respond to depression
This narrative review explores the molecular and structural mechanisms of transcranial magnetic stimulation (TMS) in treatment-resistant dep…
New research explores how magnetic pulses may reshape brain cell activity and connections for people with treatment-resistant depression.
Transdiagnostic psychological mechanisms like hopelessness and repetitive negative thinking associate with suicidal ideation in students
Identifying the psychological factors linked to suicidal ideation in students
This systematic review of 68 observational studies examines transdiagnostic psychological mechanisms related to suicidal ideation in univers…
New research highlights how feelings of hopelessness and perfectionism contribute to suicidal thoughts in university students.
FDA Approves Enspryng (satralizumab-mwge) for Anti-AQP4 Positive Neuromyelitis Optica Spectrum Disorder
FDA approves new injectable drug for rare autoimmune nerve disorder
The FDA approved Enspryng (satralizumab-mwge) for adult patients with neuromyelitis optica spectrum disorder (NMOSD) who are anti-aquaporin-…
The FDA approved Enspryng for adults with neuromyelitis optica spectrum disorder who test positive for a specific antibody. It is given as a…
Tunisian Guideline Offers 96 Evidence-Based Recommendations for Autism Care
New Autism Guideline Sets 96 Recommendations For Tunisia
This is a clinical practice guideline for autism spectrum disorder in Tunisia, developed using the ADAPTE framework and based on the 2023 Si…
A new autism guideline for Tunisia offers 96 evidence-based recommendations and 87 good practice points to standardize care.
Gut microbiome dysbiosis may contribute to cognitive decline through neuroinflammation and hypertension-mediated cerebrovascular injury
Gut health and blood pressure may impact brain health
This narrative review explores the gut-brain-vascular axis, proposing that gut microbiome dysbiosis contributes to cognitive decline via neu…
New research explores how an unbalanced gut and high blood pressure might work together to cause brain aging and cognitive decline.
Shared gray matter volume reductions in ventromedial prefrontal cortex and insula across schizophrenia, MDD, and AUD
Shared Brain Structure Changes Link Schizophrenia, Depression, and Alcohol Use
This meta-analysis of imaging data identifies shared gray matter volume deficits in the ventromedial prefrontal cortex, ventral anterior cin…
New research identifies shared gray matter reductions in the brain for people with schizophrenia, depression, and alcohol use disorders.
Systems-oriented One Health approach addresses structural and social barriers in family poultry disease control
New strategies help family poultry farmers control bird flu risks
This rapid review synthesizes 110 peer-reviewed publications and 27 policy documents regarding HPAI and LPAI control in family poultry syste…
Small-scale poultry farmers face unique hurdles in stopping bird flu. New research highlights how local knowledge and fair policies can impr…
Repetitive negative thinking serves as a transdiagnostic bridge between childhood trauma and depression
Repetitive negative thinking links childhood trauma to depression
This narrative review explores repetitive negative thinking (RNT) as a link between childhood trauma and depressive symptoms. The authors su…
New research highlights how repetitive negative thinking acts as a bridge between past childhood trauma and current symptoms of depression.
Dance and movement therapies linked to improved depression and anxiety symptoms, but evidence is heterogeneous
Rhythmic Dance and Movement Therapy May Help Anxiety and Depression
This narrative review examines rhythmic dance interventions (RDI) and dance/movement therapy (DMT) for depression and anxiety. The authors r…
Rhythmic dance and movement therapies are showing promise as complementary ways to improve symptoms of anxiety and depression.
Acupuncture Plus Antidepressants Lowers HAMD Scores in Chinese Depression Patients
Acupuncture combined with antidepressants may improve depression scores
In a network meta-analysis of 7,031 patients in China, adding acupuncture to SSRIs or SNRIs reduced HAMD depression scores more than SSRI mo…
Combining acupuncture with standard antidepressants may lead to greater reductions in depression scores than using antidepressants alone.
IL-5/IL-5Rα blockade provides clinically validated benefit in EGPA but requires phenotype-specific evidence for other conditions
Targeting Eosinophils Shows Promise for Specific Autoimmune Conditions
This narrative review explores the role of eosinophils and IL-5/IL-5Rα and IL-4Rα blockade in various autoimmune diseases. The authors concl…
New research highlights how targeting specific immune cells like eosinophils can help manage certain inflammatory and autoimmune diseases.
Gut-Brain Homeostatic Continuum framework proposes a multi-layered system for understanding Alzheimer disease pathogenesis
New Framework Suggests Gut Health Links to Alzheimer's Disease
This narrative review introduces the Gut-Brain Homeostatic Continuum (GBHC) as a conceptual framework for Alzheimer disease. It frames the d…
A new conceptual framework suggests Alzheimer's disease may involve a breakdown in the complex balance between gut health and brain function…
AI-driven imaging models show 0.891 pooled AUC for predicting hemorrhagic transformation in acute ischemic stroke
AI Models Show Promise in Predicting Stroke Complications
This meta-analysis of 3,541 patients evaluates AI-driven imaging-based prediction models for hemorrhagic transformation following mechanical…
New data shows that AI-driven imaging models can help predict a specific type of bleeding in patients undergoing emergency stroke procedures…
Adjunctive ESWT after botulinum toxin type A improves motor scores in post-stroke spasticity
Shock wave therapy may improve movement after stroke injections
This systematic review and three-level meta-analysis of 377 participants found that adjunctive extracorporeal shock wave therapy (ESWT) afte…
Adding shock wave therapy to botulinum toxin injections may help adults with muscle stiffness after a stroke improve their movement and dail…
Dietary habits and eating behaviors significantly modulate drug disposition and clinical performance in Parkinson's disease
Dietary Habits Influence How Parkinson's Medications Work in the Body
This systematic review examines how various dietary patterns and eating behaviors influence the pharmacokinetics and clinical efficacy of Pa…
Specific eating patterns and dietary habits can change how Parkinson's medications are processed and how well they work for patients.
NIBS combined with BCI does not improve upper extremity motor recovery compared to BCI alone
Brain Stimulation Combined With BCI Shows No Extra Benefit
This meta-analysis of stroke patients undergoing upper extremity rehabilitation found that adding non-invasive brain stimulation (NIBS) to b…
Adding brain stimulation to brain-computer interfaces does not improve arm movement for stroke patients compared to using the interface alon…
Telitacicept Shows Satisfactory Response in Complex Overlap Syndrome Case
Telitacicept Shows Potential in Rare Overlap Syndrome Case
This is a single case report describing a patient with systemic lupus erythematosus, immune-mediated necrotizing myopathy, Sjögren's syndrom…
A single case report describes a patient with four autoimmune conditions who responded well to a regimen containing telitacicept.
Mosque-based, culturally congruent, and faith-integrated interventions show good acceptability for Muslim American women's mental health
Faith-based programs show promise for Muslim and Arab American women
This scoping review of 29 studies examines mental health outcomes and help-seeking patterns among Muslim American, Arab American, and Arab M…
Faith-integrated programs in mosques offer a culturally relevant way to support mental health for Muslim and Arab American women facing uniq…
Green exercise may improve psychological well-being and reduce stress in children and adolescents
Green exercise may support mental health in children and teens
This narrative review examines the impact of green exercise on mental health in children and adolescents. The authors suggest that while gre…
Spending time in nature while being active could help children and teens feel happier and less stressed.
Meta-analysis-guided sampling plan targets 14 zoonotic and animal diseases across India
New sampling plan helps track diseases jumping from animals to humans
This meta-analysis pools prevalence estimates for 10 zoonotic and 4 transboundary animal diseases in India, reporting a range of 4 to 30% ac…
A new plan for monitoring animal diseases in India helps track infections like Q-fever and scrub typhus before they spread to people.
Photobiomodulation shows consistent anti-inflammatory effects but inconsistent clinical results in various neurodegenerative disorders
Red and near-infrared light may help certain brain disorders
This narrative review explores the role of photobiomodulation in treating Alzheimer's disease, Multiple Sclerosis, Parkinson's disease, and …
Red and near-infrared light therapy shows promise for some brain conditions, though results are mixed for others.
Acupuncture improves total clinical effective rate in patients with traumatic peripheral nerve injury
Acupuncture Shows Improved Recovery for Traumatic Peripheral Nerve Injury
This meta-analysis of 36 RCTs involving 2,798 patients found that acupuncture significantly improved the total clinical effective rate in tr…
Acupuncture may improve clinical outcomes for people suffering from traumatic peripheral nerve injuries, according to a large review of seve…
KRTCAP2 genetic burden and depression polygenic risk scores are associated with increased depression odds in Parkinson's
Genetic Factors Linked to Depression in Parkinson's Disease Patients
This meta-analysis of three population-based studies identifies genetic associations between specific genes and depression in Parkinson's di…
Specific genetic markers and a general risk score for depression were linked to higher rates of depression in patients with Parkinson's dise…
Dysregulation of intraocular immune pathways plays a central role in progressive retinal ganglion cell death
Immune Pathways Play Central Role in Glaucoma Progression
This systematic review examines the role of intraocular immune pathways, including microglia, astrocytes, and T cells, in glaucoma progressi…
New research highlights how immune system issues inside the eye may contribute to the death of nerve cells in glaucoma patients.
Migraine-associated forehead erythema may resolve rapidly with standard acute analgesic treatment
A rare skin condition linked to migraine attacks in one man
This case report and review of literature describes a patient with migraine and red forehead dot syndrome. The report notes that headache an…
A man with migraines experienced a red forehead dot that improved quickly with standard pain medicine, highlighting a rare skin-headache lin…
Efficacy of Various Brain-Computer Interface Feedback Modalities in Post-Stroke Upper-Limb Rehabilitation
Brain-computer interface training shows promise for stroke recovery
A network meta-analysis evaluates BCI-integrated modalities like robotic assistance and FES for improving motor function in post-stroke pati…
New data shows that brain-computer interface training with robotic assistance may improve arm movement for people recovering from a stroke.