This single-center randomized controlled trial investigated the effects of ultrasound-guided right stellate ganglion block (SGB) administered before anesthesia induction on patients undergoing elective gynecological laparoscopic surgery. The primary outcomes assessed postoperative sleep quality on days 1 and 2 using the Athens Insomnia Scale (AIS) and self-reported Total Sleep Time (TST). Secondary outcomes included postoperative nausea and vomiting, analgesia-related variables, perioperative hemodynamic changes, and length of hospital stay.
Results indicated that AIS scores were significantly lower in the SGB group compared with the control group, and Total Sleep Time was longer in the SGB group. The incidence of postoperative sleep disturbance was reduced in the intervention group, and the length of hospital stay was significantly shorter. No significant differences were observed between the two groups regarding preoperative sleep status.
Safety and tolerability data, including adverse events and discontinuations, were not reported in the study. The authors note that the improvement in sleep may represent an important pathway through which SGB facilitates perioperative recovery. However, the study did not report the sample size, specific effect sizes, p-values, or confidence intervals for the primary outcomes. Consequently, the clinical relevance of these findings remains uncertain without further data on statistical significance and safety profiles.
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BackgroundPostoperative sleep disturbance is highly prevalent after laparoscopic surgery and is closely associated with perioperative stress responses, impaired recovery quality, and prolonged hospital stay. However, effective interventions specifically targeting postoperative sleep remain limited. This study aimed to evaluate the effect of perioperative stellate ganglion block (SGB) on postoperative sleep in patients undergoing gynecological laparoscopic surgery.MethodsThis single-center, prospective, randomized controlled trial enrolled eligible patients undergoing elective gynecological laparoscopic surgery, who were randomly assigned to the SGB group or the control group. Patients in the SGB group received an ultrasound-guided right stellate ganglion block before anesthesia induction. Postoperative sleep quality on postoperative days 1 and 2 was assessed using the Athens Insomnia Scale (AIS) and self-reported Total Sleep Time (TST) as the primary outcomes. Secondary outcomes included postoperative nausea and vomiting (PONV), analgesia-related variables, perioperative hemodynamic changes, and length of hospital stay.ResultsCompared with the control group, patients in the SGB group had significantly lower AIS scores and longer TST on postoperative days 1 and 2. The incidence of postoperative sleep disturbance was reduced, and hospital length of stay was significantly shorter in the SGB group. No significant differences were observed in preoperative sleep status between the two groups.ConclusionPerioperative stellate ganglion block significantly improves early postoperative sleep in patients undergoing gynecological laparoscopic surgery. Improvement in sleep may represent an important pathway through which SGB facilitates perioperative recovery.Clinical trial registrationhttps://www.chictr.org.cn/showproj.html?proj=212749, identifier (ChiCTR2300078051).