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Ultrasound-guided right stellate ganglion block improves early postoperative sleep and shortens hospital stay in patients undergoing elective gynecological laparoscopic surgeryA neck injection that helped women sleep after surgery

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Key Takeaway
Consider ultrasound-guided right stellate ganglion block for improving early postoperative sleep in patients undergoing elective gynecological laparoscopic surgery.

This single-center randomized controlled trial investigated the effects of ultrasound-guided right stellate ganglion block (SGB) administered before anesthesia induction on patients undergoing elective gynecological laparoscopic surgery. The primary outcomes assessed postoperative sleep quality on days 1 and 2 using the Athens Insomnia Scale (AIS) and self-reported Total Sleep Time (TST). Secondary outcomes included postoperative nausea and vomiting, analgesia-related variables, perioperative hemodynamic changes, and length of hospital stay.

Results indicated that AIS scores were significantly lower in the SGB group compared with the control group, and Total Sleep Time was longer in the SGB group. The incidence of postoperative sleep disturbance was reduced in the intervention group, and the length of hospital stay was significantly shorter. No significant differences were observed between the two groups regarding preoperative sleep status.

Safety and tolerability data, including adverse events and discontinuations, were not reported in the study. The authors note that the improvement in sleep may represent an important pathway through which SGB facilitates perioperative recovery. However, the study did not report the sample size, specific effect sizes, p-values, or confidence intervals for the primary outcomes. Consequently, the clinical relevance of these findings remains uncertain without further data on statistical significance and safety profiles.

The sleepless nights no one talks about

You wake up from surgery. The hard part is over, right?

Not quite. For many women who have laparoscopic gynecologic surgery, the real struggle starts at night.

Pain, anxiety, and stress hormones conspire to rob them of rest — exactly when their bodies need it most.

Poor sleep after surgery isn't just annoying. It slows healing, worsens pain, and can extend hospital stays.

Doctors have long known this. But treatments aimed specifically at post-op sleep have been thin on the ground.

Sleeping pills carry their own risks. Opioid pain medicine can fragment sleep instead of helping it.

The old way vs what's new

For years, the plan was simple. Manage the pain, keep the room quiet, and hope patients drift off.

But here's the twist. A procedure originally used for chronic pain and circulation problems may offer something better.

It's called a stellate ganglion block — a numbing injection in the neck near a cluster of nerves that help control the body's stress response.

What is a stellate ganglion block?

Picture a busy switchboard in your neck. The stellate ganglion is part of the sympathetic nervous system — the "fight or flight" wiring that ramps your body up during stress.

A stellate ganglion block is a small anesthetic injection placed near that switchboard using ultrasound for guidance. It temporarily dials down the stress signal on one side.

Think of it like briefly turning down the volume on an overactive alarm clock.

How it might improve sleep

Surgery is a stress event. Stress hormones stay high for hours or days, keeping the nervous system on alert.

By calming the stress switchboard before the cut is made, doctors hoped patients would wake up with a quieter system — and sleep more naturally that first night.

Until now, that idea had more theory than proof for sleep specifically.

In this single-center randomized controlled trial, women scheduled for gynecologic laparoscopic surgery were randomly split into two groups.

One group got an ultrasound-guided stellate ganglion block before anesthesia. The other did not.

Researchers measured sleep on nights one and two after surgery using the Athens Insomnia Scale (a standard sleep questionnaire) and self-reported total sleep time.

Women who got the block reported lower insomnia scores and longer sleep on both nights.

Fewer of them met the threshold for post-op sleep disturbance.

They also went home from the hospital sooner.

A shorter stay, a smoother recovery

Shorter hospital stays mean less cost, less infection risk, and faster return to normal life.

And because sleep feeds recovery — fueling tissue repair and steadying mood — better sleep may be part of why these women did better overall.

Improving sleep may be one of the most overlooked ways to speed up surgical recovery.

Anesthesiologists have used stellate ganglion blocks for decades in pain clinics. More recently, researchers have tested them for PTSD, hot flashes, and long COVID symptoms.

Adding perioperative sleep to that list makes sense. Sleep and the stress response are deeply linked.

If future studies confirm these results, this simple add-on could become part of routine enhanced recovery protocols — the checklists hospitals use to get patients out of bed and home faster.

If you're scheduled for gynecologic laparoscopic surgery, you can't walk in and demand a stellate ganglion block today. It's not yet standard of care.

But you can ask your anesthesiologist what options your hospital offers for smoother recovery — including nerve blocks, regional anesthesia, or non-drug sleep support.

Hospitals that already do a lot of nerve blocks may be more open to adding this one.

This was a single-center trial. Results from one hospital don't always hold up elsewhere.

Sleep was measured partly by self-report, which is honest but imperfect. The study didn't use overnight sleep lab monitoring.

We also don't know if the benefit lasts beyond the first two nights.

Larger, multi-center trials are the next step. Researchers will want to test the block in other surgeries too — orthopedic, abdominal, cardiac — and see if the sleep benefit translates.

For now, this study adds to a growing picture. A small, targeted injection in the neck may do more than block pain. It may give patients something they desperately want after surgery — a real night's rest.

Study Details

Study typeRct
EvidenceLevel 2
PublishedApr 2026
View Original Abstract ↓
BackgroundPostoperative sleep disturbance is highly prevalent after laparoscopic surgery and is closely associated with perioperative stress responses, impaired recovery quality, and prolonged hospital stay. However, effective interventions specifically targeting postoperative sleep remain limited. This study aimed to evaluate the effect of perioperative stellate ganglion block (SGB) on postoperative sleep in patients undergoing gynecological laparoscopic surgery.MethodsThis single-center, prospective, randomized controlled trial enrolled eligible patients undergoing elective gynecological laparoscopic surgery, who were randomly assigned to the SGB group or the control group. Patients in the SGB group received an ultrasound-guided right stellate ganglion block before anesthesia induction. Postoperative sleep quality on postoperative days 1 and 2 was assessed using the Athens Insomnia Scale (AIS) and self-reported Total Sleep Time (TST) as the primary outcomes. Secondary outcomes included postoperative nausea and vomiting (PONV), analgesia-related variables, perioperative hemodynamic changes, and length of hospital stay.ResultsCompared with the control group, patients in the SGB group had significantly lower AIS scores and longer TST on postoperative days 1 and 2. The incidence of postoperative sleep disturbance was reduced, and hospital length of stay was significantly shorter in the SGB group. No significant differences were observed in preoperative sleep status between the two groups.ConclusionPerioperative stellate ganglion block significantly improves early postoperative sleep in patients undergoing gynecological laparoscopic surgery. Improvement in sleep may represent an important pathway through which SGB facilitates perioperative recovery.Clinical trial registrationhttps://www.chictr.org.cn/showproj.html?proj=212749, identifier (ChiCTR2300078051).
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