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Systematic review examines yoga effects on brain structure and function in healthy participants across 23 studies.

Systematic review examines yoga effects on brain structure and function in healthy participants acro…
Photo by Ben Maffin / Unsplash
Key Takeaway
Note heterogeneity and definitional issues limit certainty regarding yoga's impact on brain structure and function in healthy participants.

This systematic review evaluates the impact of yoga on human brain structure and function by pooling data from 23 international peer-reviewed neuroimaging studies involving healthy participants. The scope encompasses a broad range of yoga practices without a standardized definition, which contributes to the observed variability in results. The review does not report specific adverse events, tolerability data, or a consistent comparator group, as these details were not available in the source studies.

The authors synthesize that yoga may exert multiple effects on brain structure and function. However, the pooled analysis is constrained by substantial heterogeneity in results, differences in sample characteristics, and variations in study designs. Additionally, the lack of a consistent definition of yoga and the failure to distinguish between yoga and meditation practices further complicate the interpretation of the synthesized data. No specific effect sizes, p-values, or confidence intervals are reported for the primary outcome.

Limitations acknowledged by the authors include the diversity of yoga protocols and the inability to draw definitive causal conclusions due to the observational nature of many included studies. The review does not provide specific practice recommendations or quantify the clinical relevance of the findings. Consequently, while the data suggests potential benefits, the evidence is insufficient to support broad clinical implementation without further high-quality research.

Study Details

Study typeMeta analysis
EvidenceLevel 1
PublishedApr 2026
View Original Abstract ↓
Yoga is a mind–body practice that originated in India thousands of years ago, and which has extended throughout the world in recent years. As it becomes more popular, more studies are being conducted regarding its health benefits in multiple areas, including the human brain, where results have shown that it can reduce stress, modulate neurotransmitters, increase cerebral blood flow, and affect brain structure and function. This review aims to provide a synthesis of the current knowledge on the impact of yoga on human brain structure and function, through the selection and analysis of 23 international peer-reviewed neuroimaging studies with healthy participants. These studies were selected from 216 results on Web of Science, PubMed and PsycInfo after applying the inclusion and exclusion criteria. The final set of studies employed both neuroimaging and neurophysiological techniques, including MRI, fMRI, and EEG. The results show that yoga may exert multiple effects on the brain. However, the heterogeneity of results may be explained by differences in sample characteristics, study designs, and the lack of a consistent definition of yoga and its distinction from meditation. Finally, the limitations of the present review are discussed, along with recommendations for future research aimed at better understanding the neuropsychological health benefits of yoga.
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