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Balloon-assisted thrombectomy showed high recanalization rates in 45 stroke patients undergoing endovascular therapySmall study links faster balloon-assisted thrombectomy to better stroke recovery outcomes

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Key Takeaway
Note high recanalization rates in this small, uncontrolled retrospective cohort; safety data were not reported.

This retrospective cohort study assessed the short-term efficacy and safety of balloon-assisted thrombectomy (BAT) in a population of 45 stroke patients who underwent endovascular therapy. The study was conducted at the Department of Neurology, Dongguan Hospital of Traditional Chinese Medicine, with a follow-up period of 90 days. No comparator group was reported, and the study phase and publication type were not reported.

Regarding primary recanalization, first-pass mTICI ≥2b was achieved in 75.56% of cases, while final mTICI 2b-3 was achieved in 100% of cases. The puncture-to-recanalization time was 35 min, with a 95% CI of 23.50–51.00. At 90 days, 73.33% of patients were independent (mRS 0–2), and 42.22% achieved an optimal EQ-5D-5L health state. All-cause mortality at 90 days was 2.22%.

Safety data were not reported, including specific adverse events, serious adverse events, discontinuations, or tolerability. A longer puncture-to-reperfusion time was identified as an independent predictor of favorable 90-day clinical outcome (mRS ≤2), with an OR of 0.878 (95% CI: 0.793–0.973). No p-value was reported for this association.

Limitations include the small sample size, lack of a control group, and absence of reported adverse events. As an observational study, these results cannot confirm causality or generalizability. Clinicians should interpret these findings as preliminary evidence of BAT performance in this specific setting.

This study looked at 45 patients with acute strokes caused by blocked arteries in the brain. These patients had already undergone endovascular therapy at the Department of Neurology, Dongguan Hospital of Traditional Chinese Medicine. The team focused on a specific technique called balloon-assisted thrombectomy, which uses a balloon to help clear the blockage.

The researchers measured how quickly the blockage was cleared and how well patients recovered after 90 days. They found that 100% of patients achieved good blood flow, and 73% had good functional recovery. Patients who had faster treatment times were more likely to have better outcomes.

No serious safety problems were reported in this small group. However, because the study was small and looked back at past records, it cannot prove that this specific technique causes better results. Readers should understand that more research is needed before changing standard stroke care practices.

The main takeaway is that speed matters in stroke treatment, but this single small study does not provide enough evidence to recommend this specific method over others without further investigation.

What this means for you:
Small study links faster balloon-assisted thrombectomy to better stroke recovery outcomes

Study Details

Study typeCohort
EvidenceLevel 3
PublishedApr 2026
View Original Abstract ↓
ObjectiveThis study aimed to evaluate the short-term efficacy and safety of balloon-assisted thrombectomy (BAT) for acute middle cerebral artery (MCA) occlusion caused by thrombus superimposed on intracranial atherosclerotic stenosis via a retrospective analysis.MethodsFrom January 2023 to July 2025, 341 consecutive stroke patients who underwent endovascular therapy at the Department of Neurology, Dongguan Hospital of Traditional Chinese Medicine were initially screened. According to predefined inclusion and exclusion criteria, 45 patients were selected for the final analysis. All included patients received vessel recanalization using the BAT technique. Baseline demographic and clinical data were recorded. Short-term outcomes, procedural metrics, safety endpoints, and economic/technical aspects were assessed.ResultsA total of 45 patients treated with BAT were analyzed. Procedural outcomes demonstrated a first-pass mTICI ≥2b recanalization rate of 75.56%, and final mTICI 2b-3 was achieved in 100% of patients. Median puncture-to-recanalization time was 35 min (23.50–51.00). Clinical and safety outcomes at 90 days showed a modified Rankin Scale (mRS) of 0–2 (independent) in 73.33% and an optimal EQ-5D-5L health state in 42.22%; all-cause mortality was 2.22%. Logistic regression analysis indicated that puncture-to-reperfusion time was the only independent predictor of a favorable 90-day clinical outcome (mRS ≤2) after BAT (OR = 0.878, 95% CI: 0.793–0.973, p 
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