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Balloon-assisted thrombectomy showed high recanalization rates in 45 stroke patients undergoing endovascular therapy.

Balloon-assisted thrombectomy showed high recanalization rates in 45 stroke patients undergoing endo…
Photo by Dan Meyers / Unsplash
Key Takeaway
Note high recanalization rates in this small, uncontrolled retrospective cohort; safety data were not reported.

This retrospective cohort study assessed the short-term efficacy and safety of balloon-assisted thrombectomy (BAT) in a population of 45 stroke patients who underwent endovascular therapy. The study was conducted at the Department of Neurology, Dongguan Hospital of Traditional Chinese Medicine, with a follow-up period of 90 days. No comparator group was reported, and the study phase and publication type were not reported.

Regarding primary recanalization, first-pass mTICI ≥2b was achieved in 75.56% of cases, while final mTICI 2b-3 was achieved in 100% of cases. The puncture-to-recanalization time was 35 min, with a 95% CI of 23.50–51.00. At 90 days, 73.33% of patients were independent (mRS 0–2), and 42.22% achieved an optimal EQ-5D-5L health state. All-cause mortality at 90 days was 2.22%.

Safety data were not reported, including specific adverse events, serious adverse events, discontinuations, or tolerability. A longer puncture-to-reperfusion time was identified as an independent predictor of favorable 90-day clinical outcome (mRS ≤2), with an OR of 0.878 (95% CI: 0.793–0.973). No p-value was reported for this association.

Limitations include the small sample size, lack of a control group, and absence of reported adverse events. As an observational study, these results cannot confirm causality or generalizability. Clinicians should interpret these findings as preliminary evidence of BAT performance in this specific setting.

Study Details

Study typeCohort
EvidenceLevel 3
PublishedApr 2026
View Original Abstract ↓
ObjectiveThis study aimed to evaluate the short-term efficacy and safety of balloon-assisted thrombectomy (BAT) for acute middle cerebral artery (MCA) occlusion caused by thrombus superimposed on intracranial atherosclerotic stenosis via a retrospective analysis.MethodsFrom January 2023 to July 2025, 341 consecutive stroke patients who underwent endovascular therapy at the Department of Neurology, Dongguan Hospital of Traditional Chinese Medicine were initially screened. According to predefined inclusion and exclusion criteria, 45 patients were selected for the final analysis. All included patients received vessel recanalization using the BAT technique. Baseline demographic and clinical data were recorded. Short-term outcomes, procedural metrics, safety endpoints, and economic/technical aspects were assessed.ResultsA total of 45 patients treated with BAT were analyzed. Procedural outcomes demonstrated a first-pass mTICI ≥2b recanalization rate of 75.56%, and final mTICI 2b-3 was achieved in 100% of patients. Median puncture-to-recanalization time was 35 min (23.50–51.00). Clinical and safety outcomes at 90 days showed a modified Rankin Scale (mRS) of 0–2 (independent) in 73.33% and an optimal EQ-5D-5L health state in 42.22%; all-cause mortality was 2.22%. Logistic regression analysis indicated that puncture-to-reperfusion time was the only independent predictor of a favorable 90-day clinical outcome (mRS ≤2) after BAT (OR = 0.878, 95% CI: 0.793–0.973, p 
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