Mode
Text Size
Log in / Sign up

Patients with migration background had higher rates of delayed presentation and lower EVT rates after first-ever ischemic strokeWhy some stroke patients miss the window for life-saving treatment

AI-generated summary of the cited source, checked by automated accuracy review. How we work

Key Takeaway
Note that patients with migration background present later and receive EVT less frequently in this single-center cohort.

This observational cohort study included 232 patients with a first-ever ischemic stroke presenting to a Dutch Comprehensive Stroke Center. The analysis compared patients with a migration background against those without a migration background regarding presentation timing, reperfusion therapy, and clinical characteristics. The study was conducted at a single center in the Netherlands.

Patients with a migration background were more likely to present outside the therapeutic time window, with an odds ratio of 1.90 (95% CI 1.05-3.45). Specifically, 53.2% of this group presented late compared to 37.1% of the comparator group. Conversely, endovascular thrombectomy (EVT) was less frequent in patients with a migration background (8.1% vs 22.4%, OR 0.28, 95% CI 0.10-0.75).

Demographic and stroke characteristics differed between groups. Patients with a migration background were younger (66.6 vs 71.2 years) and had a higher prevalence of diabetes (27.4% vs 15.9%). Small vessel disease was more common in this group (69.4% vs 48.2%), whereas cardio-embolism was less common (4.8% vs 15.3%). Sex distribution was similar (59.7% vs 60.6% male). Door-to-treatment time (38min vs 30min), door-to-needle time (35min vs 26min), and door-to-groin time (64min vs 54min) showed no significant differences.

Safety data, including adverse events, were not reported. The study is limited by its single-center design. Associations observed may reflect prehospital and within-hospital barriers rather than inherent patient factors. Further insight is needed to address facilitators and barriers for appropriate management of this population.

Imagine waking up with sudden weakness. You call 911. But for some, the clock starts ticking differently.

Stroke is a medical emergency. Time is brain. Every minute counts when blood flow stops.

New research shows a gap in how quickly people get help. Some groups face longer waits before care begins.

Why arrival time matters most

Think of a clot like a plug in a pipe. Clear it fast, and flow returns. Wait too long, and damage sets in.

Doctors call this the therapeutic window. It is the short time after symptoms start when treatment works best.

Patients with a migration background arrived outside this window more often. Over half missed the chance for early care.

This delay happens before they even reach the hospital doors. It is not about the doctors' speed once they are inside.

Who gets the life-saving procedure

Some patients need advanced surgery to remove clots. This is called endovascular thrombectomy.

Fewer patients with a migration background received this procedure. Only 8 percent got it compared to 22 percent of others.

This doesn't mean the hospital treated them slower once they arrived.

Treatment times inside the hospital were similar for everyone. The difference happened before they walked in the door.

Younger patients with a migration background also had more diabetes. This adds another layer of health risk to manage.

Barriers hidden before the hospital

Why do some people arrive later? Researchers say we need to look at prehospital barriers.

Language might be a factor. Cultural understanding of symptoms varies. Trust in the medical system plays a role too.

Some patients might not recognize the signs of a stroke. Others might wait to see if symptoms go away.

The study focused on one Dutch hospital. Results might differ in other countries or cities.

What doctors say next

Experts say we need to understand these barriers better. We must find ways to help everyone get care faster.

More research is needed to fix these gaps. We need to know what stops people from calling for help.

Doctors urge families to learn the warning signs. Know the symptoms and act immediately.

Stroke symptoms include face drooping, arm weakness, and speech trouble. Call emergency services right away.

This study was small and focused on one location. It is a starting point, not the final word.

Larger studies will help confirm these findings. We need to see if this happens everywhere.

Approval for new treatments takes time. But understanding these gaps can improve care today.

We must work to ensure no one waits too long. Every second counts when saving a life.

The goal is equal care for all patients. We need to close the gap in arrival times.

Research continues to find better ways to reach everyone. The focus is on saving brains and lives.

More funding and awareness campaigns could help. We need to reach communities that are often missed.

The path forward requires teamwork between doctors and communities. We must build trust and understanding together.

Time is the enemy in stroke care. We must beat the clock for everyone.

Study Details

Study typeCohort
Sample sizen = 232
EvidenceLevel 3
PublishedApr 2026
View Original Abstract ↓
Objective: To assess ethnic disparities in time to hospital presentation, use of acute reperfusion therapies, and in-hospital treatment times among patients presenting with stroke in a Dutch emergency department. Methods: In this single-centre observational cohort study, we included patients with a first-ever ischemic stroke between September 2020 and September 2021. Patients were categorized by ethnicity (with or without migration background). Demographic and stroke characteristics were compared between groups. Outcomes included: rates of presentation outside therapeutic time window, acute reperfusion therapy (intravenous thrombolysis (IVT) and endovascular thrombectomy (EVT)), and, when applicable, door-to-treatment time (DTTT), with a door-to-needle time (DTNT) and door-to-groin time (DTGT) for IVT and EVT respectively. Univariable and multivariable linear and logistic regression analyses were performed, adjusted for age, sex, and NIHSS at presentation, where appropriate. Results: A total of 232 patients were included, of whom 62 (26.7%) had a migration background. These patients were younger (66.6 vs 71.2 years) and more frequently had diabetes (27.4% vs 15.9%). Sex distribution was similar (59.7% vs 60.6% male). Stroke etiology differed between groups with less cardio-embolism (4.8% vs 15.3%) and more small vessel disease (69.4% vs 48.2%) among patients with a migration background. These latter patients presented more often outside the therapeutic time window (53.2% vs 37.1%; OR 1.90; 95% CI 1.05-3.45). EVT was less frequently performed in patients with a migration background compared to those without (8.1% vs 22.4%; OR 0.28; 95% CI 0.10-0.75). There were no significant differences in treatment times (DTTT 38min vs 30min, DTNT 35min vs 26min, DTGT 64min vs 54min). Conclusion: Patients with a migration background were more likely to present outside the therapeutic time window and had a lower rate of EVT. In order to improve access for these patients, more insight into prehospital and within hospital barriers and facilitators for appropriate management are needed.
Free Newsletter

Clinical research that matters. Delivered to your inbox.

Join thousands of clinicians and researchers. No spam, unsubscribe anytime.