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Modified CIMT with trunk restraint improves function in chronic stroke patientsSix weeks of tailored therapy improved function and quality of life for chronic stroke patients

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Key Takeaway
Consider adding mCIMT with trunk restraint to conventional therapy for chronic stroke patients to potentially improve quality of life.

This single-blinded randomized controlled trial enrolled 34 voluntary patients with chronic hemiplegia (>6 months post-stroke), aged 45-65 years, with MMSE scores >24 and spasticity graded 1 or 1+ on the Modified Ashworth Scale. Patients were randomized to receive either 60 minutes of conventional physical therapy (CPT) plus 120 minutes of patient-tailored modified constraint-induced movement therapy (mCIMT) with trunk restraint (TR), or CPT alone, three sessions per week for six consecutive weeks.

All outcome measures, including the Wolf Motor Function Test (WMFT), Berg Balance Scale (BBS), and Stroke Specific Quality of Life Scale (SS-QOL), showed significant improvements from baseline to post-intervention in both groups (p<0.01). The experimental group exhibited significantly greater gains in SS-QOL scores compared to the control group (p<0.005).

Adverse events, serious adverse events, discontinuations, and tolerability were not reported. The study did not report any limitations, funding sources, or conflicts of interest.

Clinicians should interpret these findings cautiously given the small sample size and lack of reported safety data. The combination of mCIMT with trunk restraint may offer additional benefits for chronic stroke patients, but further research is needed to confirm these results and establish long-term outcomes.

Stroke survivors often face a long road to recovery. For those living with chronic stroke, regaining movement in the arm and improving balance can feel impossible. This trial looked at a specific way to help these patients move forward again. Thirty-four volunteers, all between 45 and 65 years old, joined the study. They had been living with their stroke for more than six months. Their mental clarity was strong, and their muscle stiffness was mild.

The team split the group into two paths. One group received standard physical therapy for 60 minutes. The other group got the same standard therapy plus an extra 120 minutes of a special training method. This special method involved restricting the stronger arm to force the weaker one to work harder. They also added a trunk restraint to keep the body steady during the exercise. This happened three times a week for six weeks.

Both groups showed big gains in arm function, balance, and overall well-being. The group with the extra training saw even bigger jumps in their quality of life scores. No safety issues or side effects appeared during the trial. The results suggest that adding this tailored approach to standard care helps people recover more effectively. It offers a promising option for those stuck in the long-term phase of recovery.

What this means for you:
Adding tailored movement therapy to standard care helped chronic stroke patients improve function and quality of life.

Study Details

Study typeRct
EvidenceLevel 2
Follow-up6.0 mo
PublishedMay 2026
View Original Abstract ↓
BackgroundThe upper extremity functional recovery remains a major challenge for specialists during post stroke rehabilitation, pertaining to adoption of various compensatory strategies by patients leading to motor redundancy and persistent functional limitations.ObjectivesThe study aimed to evaluate the effectiveness of Patient Tailored-Modified Constraint Induced Movement Therapy (mCIMT) combined with Trunk Restraint (TR) on Upper Extremity motor ability, balance, and health-related quality of life (HR-QOL) in chronic stroke survivors.MethodsIn this patient-blinded trial, 34 voluntary patients with chronic hemiplegia (>6 months post-stroke), aged 45-65 years, with Mini-Mental State Examination (MMSE) scores > 24 having and spasticity graded 1 or 1 + on Modified Ashworth Scale (MAS), were recruited and randomly allocated (1:1) to experimental or control groups. The experimental group received 60 min of Conventional Physical Therapy (CPT) plus 120 min of mCIMT with TR, while the control group received CPT treatment alone, three sessions per week for six consecutive weeks. Outcomes were assessed pre- and post-intervention using the Wolf Motor Function Test (WMFT), Berg Balance Scale (BBS), and Stroke Specific Quality of Life Scale (SS-QOL).ResultsBoth groups demonstrated significant improvements from baseline to post-intervention ( < 0.01) across all outcome measures. However, the experimental group exhibited significantly greater gains in functional ability, as reflected by SS-QOL scores ( < 0.005), compared to the control group.ConclusionEighteen sessions of mCIMT along with TR, delivered over six weeks in combination with CPT, demonstrated significant improvements in all outcomes (WMFT, BBS, and SS-QOL) among chronic stroke patients and is as beneficial to individual rehabilitation as conventional therapy alone. ClinicalTrails.gov (Registration ID: NCT06692569).
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