Delayed presentation and comorbidities increase total annual acute stroke care costs in Addis Ababa.
This prospective, cross-sectional cost-of-illness study assessed the total cost of acute stroke care per patient per year among 99 survivors admitted to two specialized hospitals in Addis Ababa, Ethiopia. The analysis included direct and indirect costs as secondary outcomes, with data collected over a one-year follow-up period. No adverse events, serious adverse events, discontinuations, or tolerability data were reported, as these metrics are not applicable to a cost-of-illness study design.
The median total cost of acute stroke care per patient per year was $286. Direct costs accounted for $193.77 of this total, while indirect costs were $74. Adjusted cost ratios indicated that delayed hospital presentation (arrival >4.5 h after symptom onset) was associated with a ratio of 1.78. ICU admission corresponded to an adjusted cost ratio of 1.56. Older age and the presence of at least one comorbid condition each yielded an adjusted cost ratio of 1.27. Rural residence was associated with an adjusted cost ratio of 1.40.
The study design limits the ability to establish causal relationships between patient characteristics and increased costs. Additionally, the sample size of 99 patients from a single region may limit the generalizability of these cost estimates to other settings. Understanding the cost of stroke in Ethiopia is critical for planning the implementation of acute care services, including stroke treatments, under universal health coverage, ensuring that all stroke patients benefit.