Preoperative nutritional status associates with postoperative AKI and mortality in AAA patients undergoing open repair.

This retrospective, monocentric, observational study included 125 patients with abdominal aortic aneurysm admitted for open surgical repair. The primary outcomes assessed were postoperative acute kidney injury (AKI) and 30-day mortality, while rupture at presentation was a secondary outcome. Preoperative nutritional status was evaluated using albumin, total protein, Prognostic Nutritional Index (PNI), and the CONUT Score.

patient demographics showed an average age of 72.6 ± 7.5 years, with 83.2% of the cohort being male. At presentation, 56.0% of patients had a ruptured aneurysm. Postoperative AKI occurred in 20.0% of patients, and 30-day mortality was 47.2%.

Patients with poor outcomes demonstrated lower levels of albumin, total protein, and PNI, alongside higher CONUT Scores. These associations were statistically significant, with all p-values less than 0.05. Safety considerations included the high rates of postoperative AKI, rupture at presentation, and mortality inherent to the surgical population.

Key limitations include the observational nature of the study, which precludes causal conclusions, and the lack of reported data regarding specific adverse event discontinuations or tolerability. The study was conducted in a single hospital setting. Clinicians should interpret these findings as associations rather than evidence of efficacy for specific nutritional interventions.