Mode
Text Size
Log in / Sign up

Oro-esophageal vs Nasogastric Tube Feeding in Ischemic Stroke with Dysphagia: A ProtocolNew trial tests which feeding tube helps stroke best

AI-generated summary of the cited source, checked by automated accuracy review. How we work

Key Takeaway
Note that this is a protocol; no results are available to guide clinical decisions on tube feeding in ischemic stroke with dysphagia.

This is a protocol for a multicenter randomized controlled trial that will enroll 422 ischemic stroke patients with dysphagia who require tube feeding. The intervention is oro-esophageal tube feeding, compared with standard nasogastric tube feeding. The primary outcome is dysphagia severity measured by the Dysphagia Outcome and Severity Scale (DOSS). Secondary outcomes include time to improvement of one level from baseline DOSS, time to oral intake, accumulation of secretions (Murray Secretion Scale), pharyngeal residue (Yale Pharyngeal Residual Severity Rating Scale), airway protection (Penetration-Aspiration Scale), and aspiration symptoms. Follow-up for aspiration symptoms is 6 weeks. Safety data such as adverse events, serious adverse events, discontinuations, and tolerability are not reported in this protocol. Limitations include that this is a protocol only; no results are available. The study aims to provide evidence-based support for the effects of tube feeding on swallowing-related rehabilitation outcomes. Clinicians should await results before changing practice.

Many stroke survivors wake up unable to swallow their own food or water. This problem makes eating dangerous and slows down recovery. Families often worry about the best way to feed their loved ones during this hard time.

Doctors currently use two main tubes to help these patients eat. One goes through the nose and the other through the mouth. Both methods work to get nutrients into the body. But no one knows for sure which one helps the throat heal better.

Why this choice matters now

Swallowing problems happen in many stroke patients. It is a common issue that affects daily life. Without proper nutrition, healing takes much longer. Patients also risk food or liquid going into their lungs. This can cause serious infections like pneumonia.

Current guidelines do not say which tube is better. Some doctors prefer the nose tube because it is easy to place. Others like the mouth tube because it feels more natural. This uncertainty leaves families guessing about the right choice.

A new comparison begins

But here is the twist. A large new study has started to answer this question. It will compare the two methods side by side. This is the first time researchers are testing them this way.

The goal is to see which tube helps the throat recover faster. They want to know if one method reduces the risk of choking. They also want to see which one helps patients eat by mouth sooner.

How the tubes work differently

Think of the throat like a door that needs to open and close. The nose tube sits right behind the nose and blocks part of the way. The mouth tube sits lower and might allow more space for the throat muscles.

This difference could change how well the muscles work during healing. One tube might act like a wall that stops movement. The other might act like a guide that helps the muscles move.

The study setup

This trial involves 422 patients with ischemic stroke. All of them have trouble swallowing and need a tube to eat. They will be split into two groups randomly. One group gets the nose tube and the other gets the mouth tube.

Both groups will get the same amount of care and therapy. They will receive standard rehabilitation for 15 days. The doctors will track how their swallowing improves over time.

What they hope to find

The main goal is to measure swallowing severity. Doctors will use a special scale to check progress. They will also watch how long it takes to eat by mouth again.

Another key point is safety. They will check for signs of fluid going into the airway. This is called aspiration and it is a major risk. The study will run for six weeks to see the results.

This trial is designed to give clear answers to doctors and families.

Expert perspective on the data

Researchers in Eastern Asia often use these tubes frequently. They want to make sure the best method is used everywhere. This study aims to provide evidence for better care.

It is important to note that this is a protocol. The results are not in yet. The team is just starting to collect the data. They hope to publish the findings once the work is done.

If you have a loved one with a stroke, this news is relevant. You might be asked to choose a feeding tube soon. Knowing that a study is comparing them gives you peace of mind.

Talk to your doctor about the options available now. Ask if they have any experience with either tube. Do not wait for the study results to make a decision.

The limitations to know

This study is still in the early stages. It has not finished collecting data yet. The results might change as more patients are added.

Also, the study focuses on ischemic stroke only. Other types of strokes might need different care. The findings might not apply to everyone with swallowing issues.

Doctors will wait for the data to be analyzed fully. This process takes time to ensure accuracy. Once the results are ready, they will share them with the medical community.

This work could change how doctors treat stroke patients in the future. It might help save lives and improve recovery times. Until then, families should follow the advice of their care team.

Study Details

Study typeRct
EvidenceLevel 2
PublishedApr 2026
View Original Abstract ↓
BackgroundEnteral nutrition is commonly practiced for ischemic stroke survivors with dysphagia. In Eastern Asia, nasogastric and oro-esophageal tubes are the mainstream options. However, there is a lack of rigorous clinical evidence on the effects of these two feeding methods on swallowing-related rehabilitation outcomes and clinical relevance.ObjectivesThis study is clinically oriented and aims to assess the effect of nasogastric versus oro-esophageal tube feeding on the degree and speed of dysphagia improvement, and aspiration symptoms.MethodsThis multicenter randomized controlled trial will include 422 ischemic stroke patients with dysphagia who require tube feeding. Stratified randomization will be performed to assign participants 1:1 to the oro-esophageal or nasogastric groups. All participants will receive 15-days routine rehabilitation care and nasogastric or oro-esophageal feeding, according to their group assignment.OutcomesThe primary outcome is the dysphagia severity assessed using the Dysphagia Outcome and Severity Scale (DOSS). The secondary outcomes include time to improvement of one level from the baseline DOSS, time to oral intake, accumulation of secretions assessed using the Murray Secretion Scale, pharyngeal residue after swallowing assessed using the Yale Pharyngeal Residual Severity Rating Scale, and airway protection assessed using the Penetration-Aspiration Scale. Aspiration symptoms will be monitored for 6 weeks.DiscussionThis study aims to provide evidence-based support for the comprehensive effects of tube feeding on swallowing-related rehabilitation outcomes.Clinical trial registrationClinicalTrials.gov, identifier NCT07386834.
Free Newsletter

Clinical research that matters. Delivered to your inbox.

Join thousands of clinicians and researchers. No spam, unsubscribe anytime.