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Cross-Sectional Ancillary Study Links Midurethral Sling to Reduced Clitoral Dimensions and Sexual Function ScoresVaginal Surgery May Shrink the Clitoris, Affecting Sexual Function

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Key Takeaway
Note that MUS use was associated with smaller clitoral dimensions and poorer sexual function scores in this cross-sectional analysis.

This cross-sectional ancillary study analyzed data from 88 women analyzed (82 analyzed in results; 45 MUS, 37 No-MUS) with uterovaginal prolapse across eight clinical sites in the US Pelvic Floor Disorders Network. Participants underwent vaginal mesh hysteropexy or vaginal hysterectomy with uterosacral ligament suspension with or without midurethral sling (MUS). Follow-up occurred at 24-48-month follow-up for sexual activity and function, with MRI 30-42 months after surgery (or earlier if reoperation was desired).

Postoperatively, 25 MUS, 12 No-MUS, 20 hysteropexy, and 17 hysterectomy patients were sexually active. Regarding function, the MUS group had a poorer PISQ-IR arousal/orgasm score than the No-MUS group, with a median 3.5 vs 4.3 (P=.02). The hysteropexy group had less improvement than the hysterectomy group, showing a median 0.0 vs 0.3 (P=.01).

Anatomical findings showed women with MUS had a smaller clitoral glans thickness than without MUS, with a median 9.0 mm vs 10.0 mm (P=.008). Similarly, women with MUS had a smaller clitoral body volume, with a median 2783.5 mm3 vs 3587.4 mm3 (P=.01). Safety data including adverse events and discontinuations were not reported.

Authors note that future studies should explore surgery-induced changes in clitoral anatomy and sexual function. Practice relevance suggests women with MUS or hysteropexy experienced poorer postoperative sexual function. The observational design precludes inferring causation from these associations. Funding or conflicts were not reported.

A Hidden Side Effect

Imagine recovering from surgery, only to notice something feels different in your body—something you can’t quite name. For many women, sexual changes after pelvic surgery are a quiet, unspoken concern.

A new study using detailed MRI scans has found a link between a common bladder surgery and changes in clitoral size and sexual function.

Pelvic organ prolapse and urinary incontinence affect millions of women, especially after childbirth or as they age. These conditions can be uncomfortable and embarrassing.

To fix these issues, surgeons often use a midurethral sling (MUS)—a small mesh strip that supports the bladder to prevent leaks. They also perform vaginal surgeries to repair a dropped uterus or vaginal wall.

But these procedures are close to the clitoris, a key organ for sexual pleasure. Until now, it wasn’t clear if surgery affected it.

The Surprising Shift

For years, the focus has been on whether surgery fixes the physical problem. But what about sexual function?

This study found that women who had a midurethral sling reported poorer sexual function after surgery compared to those who did not have the sling. They also had a smaller clitoris on MRI scans.

Here’s the twist: the type of vaginal surgery mattered too. Women who had a hysteropexy (uterus-sparing surgery) reported less improvement in sexual function than those who had a full hysterectomy.

How It Works: A Simple Analogy

Think of the clitoris like a small, sensitive switch. It’s located right next to the vagina and bladder area.

When a surgeon places a mesh sling or repairs the vaginal wall, they are working in a tight space. Even with careful technique, swelling, scar tissue, or changes in blood flow could affect the clitoris—like accidentally bumping a switch while fixing a nearby wire.

This study suggests that the sling itself, or the tension it creates, might put subtle pressure on the clitoris, potentially changing its size and function over time.

Researchers looked at 88 women who had vaginal surgery for pelvic organ prolapse between 2013 and 2015. About half had a midurethral sling added for incontinence.

They used MRI scans taken 30–42 months after surgery to measure clitoral size and position. They also surveyed women about their sexual function using a standard questionnaire.

First, the good news: overall, sexual function did not worsen for most women after surgery. Many reported staying the same or even improving.

But there was a clear difference between groups.

Women who had a midurethral sling had lower scores in arousal and orgasm compared to those without a sling. On MRI, their clitoral glans was thinner (9 mm vs. 10 mm) and their clitoral body volume was smaller (about 2,800 mm³ vs. 3,600 mm³).

Similarly, women who had hysteropexy had less improvement in sexual function than those who had a hysterectomy.

This doesn’t mean the sling is harmful for everyone.

Where Experts Stand

Researchers note that these findings are based on a specific group of women and should be interpreted with caution. The study shows a link, not a cause-and-effect.

They suggest that future studies should look more closely at how surgery changes clitoral anatomy and function over time.

If you’re considering pelvic surgery, talk to your doctor about potential sexual side effects. Ask about the type of sling used and whether there are alternatives.

This study does not mean you should avoid necessary surgery. It highlights the importance of discussing all possible outcomes with your surgeon.

This was a small, observational study. It only included women from eight U.S. clinics, and all had specific types of vaginal surgery. The results may not apply to everyone.

MRI measurements can vary, and sexual function is subjective. The study cannot prove that surgery caused the changes—only that they are associated.

More research is needed to understand how surgery affects the clitoris and sexual function. Future studies should include larger, more diverse groups and longer follow-up.

If confirmed, these findings could help surgeons refine techniques to better preserve sexual function. For now, open communication with your healthcare team remains key.

Study Details

Sample sizen = 2,018
EvidenceLevel 5
PublishedApr 2026
View Original Abstract ↓
Importance: Sexual dysfunction can occur after midurethral sling (MUS) and transvaginal prolapse surgery. It remains unclear whether these procedures impact the clitoris, despite its role in sexual function and proximity to the MUS and vagina. Objectives: To compare postoperative sexual function and clitoral features by MUS and vaginal surgery approach after transvaginal prolapse repair with/without concomitant MUS. Design: Cross-sectional ancillary study of magnetic resonance imaging (MRI) and sexual function data from the Defining Mechanisms of Anterior Vaginal Wall Descent study. Setting: Eight clinical sites in the US Pelvic Floor Disorders Network. Participants: 88 women with uterovaginal prolapse who underwent vaginal mesh hysteropexy or vaginal hysterectomy with uterosacral ligament suspension with/without MUS between 2013-2015. Data were analyzed between September 2021-June 2023. Exposures: Between June 2014-May 2018, participants underwent pelvic MRI 30-42 months after surgery, or earlier if reoperation was desired. Sexual activity and function at baseline and 24-48-month follow-up were evaluated using the Pelvic Organ Prolapse/Incontinence Sexual Questionnaire, IUGA-Revised (PISQ-IR). Clitoral features were obtained from postoperative MRI-based 3-dimensional models. Main Outcomes and Measures: PISQ-IR scores and clitoral features (size, position). Results: Eighty-two women (median [range] age, 65 [47-79] years) were analyzed: 45 MUS (22 hysteropexy, 23 hysterectomy) and 37 No-MUS (19 hysteropexy, 18 hysterectomy). Postoperatively, 25 MUS, 12 No-MUS, 20 hysteropexy, and 17 hysterectomy patients were sexually active (SA). Overall, within the MUS and vaginal surgery groups, sexual function remained unchanged or improved (most PISQ-IR change from baseline scores were [≥]0) among SA and NSA women. Among SA women after surgery, the MUS group (vs No-MUS) had a poorer PISQ-IR arousal/orgasm (SA-AO) score (median, 3.5 vs 4.3; P=.02). The hysteropexy group (vs hysterectomy) had less improvement in PISQ-IR SA-AO score (median, 0.0 vs 0.3; P=.01). Women with MUS (vs without) had a smaller clitoral glans thickness (median, 9.0 mm vs 10.0 mm; P=.008) and clitoral body volume (median, 2783.5 mm3 vs 3587.4 mm3; P=.01). Conclusions and Relevance: SA women with MUS (vs without) or hysteropexy (vs hysterectomy) experienced poorer postoperative sexual function. MUS was linked to a smaller clitoris. Future studies should explore surgery-induced changes in clitoral anatomy and sexual function.
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