Researchers analyzed data from 2,728 adult patients who underwent a specific type of stomach surgery called endoscopic submucosal dissection (ESD). The study looked at how using fibrin glue, either alone or combined with polyglycolic acid (PGA) sheets, affected bleeding risks after the procedure.
The results showed that using both fibrin glue and PGA sheets significantly reduced the risk of delayed bleeding and overall bleeding. However, when patients received only fibrin glue without the extra sheets, the reduction in delayed bleeding was not statistically significant. The study also found no significant differences in acute bleeding or the rate of procedural perforations between the groups.
Because this analysis included both randomized trials and observational studies, the results show a link rather than a direct cause. While the combination treatment shows promise for reducing complications like symptomatic bleeding, it is important to talk with a doctor about specific surgical plans.
