Case report describes embolization and endocrine therapy for post-biopsy hematoma in prostate cancer patient

A case report and literature review describes a patient diagnosed with prostate cancer who developed extensive subcutaneous hematoma involving the lower abdomen and perineum following transperineal prostate biopsy. The patient received prompt management with prostatic artery angiography and superselective prostatic artery embolization, supplemented by endocrine therapy. No comparator treatment was reported.

The main outcome was resolution of the hematoma, which showed rapid resolution according to the report, though specific effect sizes, absolute numbers, and statistical measures were not provided. At three-month follow-up, tumor biomarkers remained stable, and key biochemical parameters had returned to pre-biopsy baseline levels. The safety profile noted the subcutaneous hematoma itself as the adverse event; serious adverse events, discontinuations, and tolerability details were not reported.

Key limitations include the nature of a single case report, which provides very low-level evidence. The report cautions that postoperative subcutaneous hematoma in the perineal region may be overlooked due to its anatomically concealed presentation, potentially leading to delayed clinical attention. Funding and conflicts of interest were not reported. The practice relevance of this isolated case for broader management of post-biopsy complications is extremely limited and requires validation in controlled studies.