Questions about Prostate Cancer
Can dose intensification improve outcomes for intermediate- or high-risk prostate cancer?
Yes, early evidence suggests dose intensification to visible tumors may improve outcomes for intermediate- or high-risk prostate cancer, but ongoing trials will clarify safety and efficacy.
Full answer →Is there more research on macrophage polarization for prostate cancer since 2015?
Yes, research on macrophage polarization in prostate cancer has grown significantly since 2015, with studies exploring its role in tumor progression and therapy resistance.
Full answer →Can enzalutamide plus ADT improve survival for metastatic hormone-sensitive prostate cancer?
Yes, enzalutamide plus ADT significantly improves survival in metastatic hormone-sensitive prostate cancer, with a 34% reduction in risk of death and a 5-year survival rate of 66% versus 53% with ADT alone.
Full answer →All Prostate Cancer Articles
- Artificial intelligence improves diagnostic accuracy and treatment planning in prostate cancer management
- PSMA-targeted radioligand therapies including 177Lu-PSMA-617 improve progression-free survival and overall survival in mCRPC
- Late grade 2 or higher gastrointestinal toxicity is inversely associated with biochemical recurrence in prostate cancer
- Post-diagnosis physical activity of 7.5 MET-hr/week associated with lower all-cause mortality in prostate cancer
- MRI-based artificial intelligence models show promise in predicting biochemical recurrence in prostate cancer
- Biparametric MRI noninferior to multiparametric MRI for detecting clinically significant prostate cancer
- PSMA-targeted radioguided surgery shows high diagnostic accuracy in prostate cancer meta-analysis
- Radiomics models predict biochemical recurrence after prostatectomy with 0.82 sensitivity
- PSMA-targeting radiotracers exhibit varying liver background uptake levels impacting patient selection for targeted therapy
- Meta Analysis Evaluates Hypokalemia Risks Associated with Androgen Receptor Axis Targeted Therapies
- Higher serum vitamin D levels linked to small increase in prostate cancer risk
- Catheterisation Linked to Small PSA Rise in Men
- Meta-analysis Evaluating Occupational Hexavalent Chromium Exposure and Specific Malignancy Risks
- Prostatic incidental uptake on FDG PET/CT has a 1.7% prevalence with 21.3% malignancy risk
- Diffusion tensor imaging metrics may improve diagnostic specificity for pelvic floor anatomical conditions
- Solid organ transplant recipients face higher cancer-related mortality with SMR 2.21 across multiple organs
- Infliximab may offer clinical improvement and wound reduction in non-Crohn's disease related fistulas
- Arecoline may upregulate androgen receptor in prostate cancer cells, integrative analysis suggests
- Aglatimagene plus valacyclovir improves disease-free survival in intermediate or high-risk prostate cancer patients
- Adding docetaxel to ADT and RT cuts mortality in high-risk prostate cancer with normal testosterone
- Long-term data reveals cribriform-positive status drives metastatic risk in prostate cancer patients
- Extraperitoneal single-port robotic-assisted radical prostatectomy shortens console time by 83 minutes versus multiport transperitoneal approaches in 1997 patients
- Intensity-modulated radiotherapy reduces acute and delayed G2+GI toxicities versus 3D-CRT in high-risk prostate cancer
- AI assistance improves diagnostic accuracy for clinically significant prostate cancer detection via MRI in this systematic review
- Local anaesthetic transperineal biopsy reduces infection and sepsis while improving cancer detection compared to transrectal ultrasonography methods
- 64 Cu-PSMA-617 shows highest detection rates in biochemically recurrent prostate cancer
- PSA-based prostate cancer screening reduces mortality but increases diagnoses
- Polygenic Risk Score Ties to Prostate Cancer Aggressiveness
- NeuroSAFE-guided robot-assisted prostatectomy improves erectile function and continence in men
- Review of bibliometric data shows growing research interest in macrophage polarization strategies for prostate cancer since 2015
- Enzalutamide plus ADT improves 5-year survival in metastatic hormone-sensitive prostate cancer
- Time to biochemical progression predicts second events in high-risk prostate cancer
- PSA levels at 6, 12, and 24 weeks post-randomization correlate with 96-month survival in prostate cancer
- MRgSBRT and replanned CTgSBRT show similar organ-at-risk dosimetry in prostate cancer
- Ultrasound-guided salvage brachytherapy with interstitial hyperthermia shows low toxicity in locally recurrent prostate cancer
- Systematic review and meta-analysis evaluates PRIMARY score on PSMA PET for prostate cancer detection
- PHS601-based stratification increases prostate cancer risk estimates in Norwegian population-based cohorts
- MRI-RSI changes during neoadjuvant ADT and radiotherapy in men with high-risk localized prostate cancer
- Narrative review evaluates urine-based PSMA detection technologies as emerging noninvasive diagnostics for prostate cancer
- Machine learning quantification of Gleason Pattern 4 showed higher discrimination for adverse pathology than grade group in prostate cancer
- Transdermal Estradiol Patches Show Noninferiority to LHRH Agonists in Prostate Cancer Metastasis-Free Survival
- Image-guided radiotherapy dose intensification for intermediate- or high-risk prostate cancer
- Enzalutamide Monotherapy Shows Higher Survival and Metastasis-Free Rates Versus Leuprolide in High-Risk Biochemical Recurrence
- Prolonged nightly fasting plus telehealth coaching showed feasibility in men with prostate cancer on androgen deprivation therapy
- ML-driven decision aid reduces decisional conflict in prostate cancer screening discussions compared to standard education
- Radical perineal prostatectomy shows lower blood loss but similar long-term outcomes to retropubic approach
- Systematic review finds PSA screening reduces prostate cancer mortality but increases overdiagnosis and false positives
- Serum triglyceride levels show no relationship with prostate cancer risk in a meta-analysis of Chinese men
- Liquid biopsy shows high sequencing success in high-risk localized prostate cancer feasibility study
- Systematic review of 2025 RCTs identifies new standards of care across genitourinary cancers
- PET-guided radiation dose escalation linked to improved event-free survival in prostate cancer recurrence
- Targeted plus perilesional biopsy noninferior to combined biopsy for prostate cancer detection
- Prior HoLEP association with longer operative time and catheter duration in subsequent RARP
- Animated video reduces pain and improves satisfaction during transperineal prostate biopsy in RCT
- Lu-PSMA-617 reduces disease progression versus deferred ADT in oligometastatic HSPC in phase 2 trial
- Phase 2 trial of muscadine grape extract added to ADT for recurrent prostate cancer fatigue
- Qualitative study finds knowledge gaps and insurance concerns about prostate cancer genetic testing