PHS601-based stratification increases prostate cancer risk estimates in Norwegian population-based cohorts
Genetic test shows higher prostate cancer risk in specific groups
This cohort study evaluated PHS601-based stratification in Norwegian population-based cohorts. The analysis included 14,688 individuals in c…
A genetic test linked to prostate cancer risk found that men in the top 1.8 percent of scores faced nearly nine times higher risk than avera…
MRI-RSI changes during neoadjuvant ADT and radiotherapy in men with high-risk localized prostate cancer
Early MRI scans shrink after treatment to help spot prostate cancer recurrence sooner
This prospective phase II trial protocol reports early results from 97 men with unfavorable-intermediate-risk or high-risk localized prostat…
New MRI scans taken before and during treatment for prostate cancer show clear shrinkage that could help doctors target the tumor more accur…
Narrative review evaluates urine-based PSMA detection technologies as emerging noninvasive diagnostics for prostate cancer.
Urine Test for Prostate Cancer Could Cut Unnecessary Biopsies
This narrative review examines urine-based PSMA detection technologies, including antibody-based immunoassays and CRISPR/Cas12a-assisted sig…
A urine test that spots a prostate cancer protein may soon make screening safer and more accurate for millions of men.
Umbrella review associates processed meat consumption with higher risks of cancer and chronic disease outcomes.
Processed meat links to higher cancer and heart disease risks
This umbrella review synthesized data from 34 articles and 54 meta-analyses regarding processed meat consumption. It reports associations wi…
Eating more processed meat like bacon or hot dogs increases your risk for serious health problems including cancer and heart disease.
Machine learning quantification of Gleason Pattern 4 showed higher discrimination for adverse pathology than grade group in prostate cancer.
AI Measures Prostate Cancer Risk More Accurately Than Standard Methods
This proof-of-principle cohort study evaluated 726 patients with grade group 2-4 prostate cancer on systematic biopsy who underwent radical …
A new AI tool can spot dangerous prostate cancer patterns better than current grading, offering men a clearer picture of what to expect afte…
Preclinical deep learning framework shows improved dose prediction for unseen cancer sites
A Heavy Burden on Doctors
This is a preclinical development study of a deep learning framework for radiotherapy dose prediction. The framework performed comparably to…
A new AI tool can plan radiation doses for many different cancers at once.
Transdermal Estradiol Patches Show Noninferiority to LHRH Agonists in Prostate Cancer Metastasis-Free Survival
Men with advanced prostate cancer may have fewer hot flashes with a new patch treatment.
This phase 3 randomized trial evaluated 1360 men with locally advanced prostate cancer across 75 U.K. centers. Transdermal estradiol patches…
A new patch for advanced prostate cancer showed similar cancer control to standard shots but caused fewer hot flashes in a large UK trial.
Narrative review offers practical recommendations for implementing PET-guided therapy workflows in clinical practice.
PET scans now guide your radiation treatment
This narrative review synthesizes evidence regarding the implementation of PET-guided therapy workflows. The authors provide practical recom…
Imagine standing in a doctor's office waiting for radiation therapy.
Image-guided radiotherapy dose intensification for intermediate- or high-risk prostate cancer
New prostate cancer radiation targets only the tumor, not the whole gland
This is a phase II randomized controlled trial protocol for patients with intermediate- or high-risk prostate cancer planning radiotherapy. …
This study tests a smarter way to deliver radiation—focusing the dose on the tumor while protecting the rest of the prostate, which could me…
Narrative review on mpMRI and PSMA PET/CT for radiorecurrent prostate cancer restaging
Two imaging tests together spot prostate cancer return more accurately
This narrative review synthesizes evidence on mpMRI and PSMA-targeted PET/CT for restaging radiorecurrent prostate cancer. The authors repor…
For men with suspected prostate cancer return, combining two scans catches more tumors and avoids unnecessary biopsies.
Enzalutamide Monotherapy Shows Higher Survival and Metastasis-Free Rates Versus Leuprolide in High-Risk Biochemical Recurrence
Enzalutamide shows better outcomes than leuprolide for high risk prostate cancer recurrence
This Phase 3 randomized controlled trial evaluated enzalutamide monotherapy versus leuprolide alone in patients with high-risk biochemical r…
Men with high-risk prostate cancer recurrence lived longer and spread less cancer when taking enzalutamide alone instead of leuprolide alone…
Proton therapy shows dosimetric advantages over photon therapy for prostate cancer treatment
Can proton therapy spare healthy tissue better for prostate cancer patients?
This review summarizes evidence on proton therapy for prostate cancer across treatment settings. Dosimetric outcomes favor proton therapy, p…
Proton therapy spares healthy tissue better than standard radiation for prostate cancer, offering excellent disease control with low rates o…