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Laparoscopic right hemicolectomy for ascending colon cancer with situs inversus totalisSurgery for colon cancer in patients with internal organ reversal

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Key Takeaway
Laparoscopic right hemicolectomy with intracorporeal anastomosis was feasible in a patient with ascending colon cancer and situs inversus totalis.

Situs inversus totalis is a rare congenital condition in which the abdominal and thoracic organs are mirrored. When ascending colon cancer occurs in this setting, the reversed anatomy makes standard surgical landmarks and approaches unfamiliar, increasing technical difficulty.

This case report and literature review describes a patient with ascending colon cancer and situs inversus totalis who underwent laparoscopic radical right hemicolectomy with intracorporeal anastomosis. The procedure was performed successfully, and the report outlines the surgical steps and anatomical considerations encountered.

The authors also reviewed the scarce published literature on this combination, noting that few clinical reports exist to guide operative planning. Because the evidence comes from a single case and a limited literature base, the findings cannot establish broader effectiveness or safety.

The report offers practical surgical experience for clinicians who may encounter this rare presentation, emphasizing the need for careful preoperative imaging and intraoperative orientation. Further reports are needed to clarify optimal techniques and outcomes.

Imagine having a rare condition where your internal organs are mirrored, like a mirror image of what is typical. This is called situs inversus totalis. When a person with this condition develops colon cancer, it creates a complex challenge for surgeons who must navigate an unfamiliar internal map to remove the tumor.

One patient with ascending colon cancer and this rare condition underwent a laparoscopic radical right hemicolectomy. This is a surgical procedure to remove the affected part of the colon using small incisions and a special connection made inside the body. The surgery was successful, providing a roadmap for how to handle these complicated cases.

Because this condition is so rare, there is very little information available for doctors to follow. This report highlights a specific successful case and reviews existing literature to help surgeons prepare for these unique situations. While the results come from just one patient, it offers valuable experience for managing cancer in patients with flipped organs.

What this means for you:
A successful surgery shows how doctors can treat colon cancer in patients with rare, mirrored internal organs.

Common questions

What is situs inversus totalis?

Situs inversus totalis is a rare condition where a person's internal organs are mirrored or flipped from their normal positions. In this specific case, it meant the patient had a different internal layout when surgeons were treating their colon cancer.

How was the colon cancer treated in this case?

The patient underwent a laparoscopic radical right hemicolectomy with intracorporeal anastomosis. This means the surgeon used small incisions to remove the cancerous part of the colon and joined the remaining ends together inside the body.

Is this a common way to treat this condition?

Because situs inversus totalis is very rare, there are very few published reports on how to treat it. This specific case provides important information for surgeons who encounter this rare condition while treating colon cancer.

Study Details

Study typeSystematic review
EvidenceLevel 1
PublishedSep 2026
View Original Abstract ↓
Ascending colon cancer complicated by situs inversus totalis (SIT) represents an extremely rare clinical entity. This congenital anatomical variant substantially increases surgical complexity, and published clinical reports regarding this condition remain scarce. Herein, we report a patient who underwent laparoscopic radical right hemicolectomy (LRH) with intracorporeal anastomosis (IA), accompanied by an operative video. We further reviewed the available published literature to accumulate additional surgical experience for managing this rare disease.
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