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Patients with Parkinson's disease exhibit deficits in sustained, selective, and divided visuospatial attentionParkinson's Disease Linked to Specific Visuospatial Attention Deficits

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Key Takeaway
Note that Parkinson's disease involves specific deficits in sustained, selective, and divided visuospatial attention.

This meta-analysis synthesizes data from 51 studies to evaluate visuospatial attentional deficits in right-handed, cognitively unimpaired patients with idiopathic Parkinson's disease compared to healthy controls. The analysis focuses on various components of attention, including sustained, selective, and divided attention, as well as orienting and alerting mechanisms.

Key findings indicate that patients with Parkinson's disease demonstrate significant deficits in sustained, selective, and divided attention, as well as impaired exogenous orienting. In contrast, alerting, endogenous orienting, and reorienting were reported as preserved in this population. Regarding visuospatial bias, the analysis noted small, context-dependent shifts in spatial attention and subtle rightward spatial tendencies in patients with left-sided Parkinson's disease (LPD).

The authors note that few studies specifically examined visuospatial bias. These findings suggest that exogenous orienting deficits and subtle rightward spatial tendencies in LPD may indicate a disruption of right-hemisphere attentional networks. These results have implications for early cognitive assessment and the development of rehabilitation strategies for patients with Parkinson's disease.

How this fits prior evidence

This meta-analysis addresses a gap in understanding the specific components of attentional dysfunction in Parkinson's disease. While previous coverage noted that the right inferior frontal gyrus serves as a consistent neural correlate for freezing of gait, this study provides evidence regarding the specific attentional networks, such as the right-hemisphere networks, that may be disrupted in these patients.

A large review of 51 studies looked at how people with Parkinson's disease manage visuospatial attention compared to healthy individuals. The study focused on patients who were cognitively unimpaired and right-handed. These types of attention tasks involve focusing on specific areas, switching focus, and reacting to new information in the environment.

The findings show that people with Parkinson's often struggle with sustained, selective, and divided attention. They also showed impairments in exogenous orienting, which is the ability to shift attention toward an external stimulus. However, the study found that alerting, endogenous orienting, and reorienting remained preserved in these patients.

Some results regarding spatial bias were small and depended on the specific context. These findings suggest that certain networks in the brain may be affected by the condition. Because the evidence on spatial bias is limited by a small number of studies, these results are primarily used to help doctors understand how the condition affects the brain and to help plan better rehabilitation strategies.

What this means for you:
People with Parkinson's may have specific difficulties with sustained and selective attention in spatial tasks.

Common questions

What specific types of attention are affected by Parkinson's?

The study found that patients with Parkinson's disease showed deficits in sustained, selective, and divided attention. They also showed impairments in exogenous orienting. These findings suggest that certain parts of the brain responsible for focusing on information in space may be affected by the condition.

Are there any types of attention that remain normal in Parkinson's?

Yes, the study found that alerting, endogenous orienting, and reorienting were preserved in the patients studied. This means these specific types of attentional processes did not show the same level of impairment as others during the evaluation.

What does the research say about spatial bias?

The results for visuospatial bias were small and depended on the context. Some patients with left-sided Parkinson's showed subtle rightward spatial tendencies. Because few studies examined this specific area, these results are not yet definitive.

Study Details

Study typeMeta analysis
EvidenceLevel 1
PublishedNov 2026
View Original Abstract ↓
Parkinson's disease (PD) is a neurodegenerative condition primarily characterized by motor deficits, yet cognitive impairments are increasingly recognized. While deficits in executive functioning are well documented even in the absence of cognitive decline, evidence of attentional deficits in PD remains inconsistent, and the role of motor symptom lateralization is unclear. In this systematic review and meta-analysis, we examined visual attention in right-handed, cognitively unimpaired idiopathic PD patients, focusing on the canonical attentional domains (sustained, selective, divided) and processes (alerting, endogenous and exogenous orienting, reorienting), as well as visuospatial bias. Four databases were searched for studies comparing PD patients with healthy controls. Meta-analytic estimates were derived using Hedges' g within random-effects models, and studies that could not be quantitatively integrated were summarized narratively. In addition, studies directly comparing patients with left- and right-predominant motor symptoms (LPD vs. RPD) were reviewed qualitatively. Across 51 studies, PD patients exhibited deficits in sustained, selective, and divided attention. Among attentional processes, only exogenous orienting was impaired, whereas alerting, endogenous orienting, and reorienting were preserved. Findings from the few studies examining visuospatial bias indicated small, context-dependent shifts in spatial attention rather than a consistent directional bias. These findings indicate that PD patients show visual-attentional impairments, particularly under high-demand conditions, while basic alertness and voluntary orienting appear preserved. Exogenous orienting deficits and subtle rightward spatial tendencies in LPD suggest disruption of right-hemisphere attentional networks. These results have implications for early cognitive assessment, rehabilitation strategies, and understanding the neural bases of attentional dysfunction in PD.
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