Researchers examined 919 eyes from 919 patients who underwent three different laser vision correction procedures: SMILE, FS-LASIK, or Trans-PRK. The goal was to see which method provided the most accurate and stable vision correction over time. Patients were followed for up to 1.5 years to track their visual outcomes and comfort levels.
The analysis found that SMILE consistently produced results closest to the ideal target. It showed the highest predictability and stability, with the least amount of vision shifting back toward nearsightedness. In contrast, Trans-PRK was associated with greater residual myopia and more regression over the follow-up period. FS-LASIK fell somewhere in between these two options.
Beyond accuracy, the study looked at eye surface health and higher-order aberrations. SMILE resulted in the lowest scores for dry eye symptoms and the lowest levels of corneal irregularities. Trans-PRK showed the highest levels of these issues. All three procedures maintained a high safety profile with very low rates of serious vision loss or the need for additional corrective surgeries.
The main reason to be careful is that this was a retrospective study using existing data, which limits how much we can conclude about cause and effect. Surgical technique was the primary factor influencing outcomes. Readers should understand that while SMILE looked superior in this group, individual results may vary. This evidence supports selecting a procedure based on patient needs to optimize comfort and accuracy.
