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Home › Conditions › Myopia

Myopia

Subtypes of Myopia

Premyopia 2

11 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Myopia

299 trials tracked for Myopia: 14 in phase 3 or 4 and 2 with published results. The most-cited published study has 120 citations.

299Trials tracked
14Phase 3 & 4
0Recruiting
2With published results
Phase distribution
Phase 4 7 Phase 3 7 Phase 2 4 Phase 1 2 Other / NA 279
  1. Phase 3 Low-Dose Atropine for Treatment of Myopia Completed · 120 cited
  2. Phase 3 CHAMP: Study of NVK-002 in Children With Myopia Completed · 118 cited
  3. Phase 4 Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface Completed
  4. Phase 4 On-Eye Optical Quality of Lotrafilcon B Lenses Over 12 Hours Completed
  5. Phase 4 Clinical Investigation of the Vision-R800 Device. Completed
  6. Phase 4 Daily Wear Corneal Infiltrative Event Study Completed
Show 44 more trials
  1. Phase 4 Contralateral Comparison of Three Excimer Laser Systems in Performing LASIK Completed
  2. Phase 4 Comparative Performance of PureVision, Acuvue Oasys and O2Optix Completed
  3. Phase 4 Corneal and Conjunctival Sensitivity and Staining Study Completed
  4. Phase 3 Safety and Efficacy Study of Topography-Guided LASIK to Treat Myopia and Hyperopia Completed
  5. Phase 3 Safety and Effectiveness of Wavefront-Guided LASIK Corrections of Myopic Refractive Errors Completed
  6. Phase 3 Comparison of Lens Care Regimens With a Silicone Hydrogel Lens (Emerald) Completed
  7. Phase 3 Comparative Performance of PureVision Lens Designs Completed
  8. Phase 3 Correction of Myopia Evaluation Trial 2 Completed
  9. Phase 2 Comparative Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions Completed
  10. Phase 2 Low-dose Atropine for the Prevention of Myopia Progression in Danish Children Completed
  11. Phase 2 Cannabinoid vs Opioid for Photorefractive Keratectomy Pain Control Completed
  12. Phase 2 Side Effects of Atropine (SEA) Study Completed
  13. Phase 1 Use of the VisuMax™ Femtosecond Laser Completed
  14. Phase 1 Phase I Clinical Trial to Evaluate the Safety and Tolerability of Ophtalmic Solution PRO-201 Completed
  15. N/A Multi-Centre Clinical Evaluation Of Two Daily Disposable Contact Lenses Completed
  16. N/A Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution Completed
  17. N/A Clinical Comparison of Two Daily Disposable Soft Contact Lenses Completed
  18. N/A Performance Comparison Between Fanfilcon A and Senofilcon A Sphere Lenses Completed
  19. N/A Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Toric Contact Lenses Completed
  20. N/A Clinical Evaluation of Two Daily Disposable Silicone Hydrogel Contact Lenses Completed
  21. N/A Subjective Comfort With Multipurpose Care Solutions in Soft Contact Lens Wearers Completed
  22. N/A A Product Performance Evaluation of a Novel Contact Lens for Daily Disposable Use Completed
  23. N/A A Study to Assess the Safety and Efficacy of a Daily Disposable Contact Lens Completed
  24. N/A A Clinical Comparison of Three Soft Daily Disposable Contact Lenses Completed
  25. N/A Clinical Evaluation of Reusable Soft Contact Lenses Completed
  26. N/A Clinical Evaluation of Stenfilcon A Soft Contact Lens When Compared to Ocufilcon B Soft Contact Lens Completed
  27. N/A Dispensing Evaluation of a Galyfilcon A Prototype Lens and a Marketed Contact Lens Completed
  28. N/A Prospective Study of Lens Performance of a Monthly Replacement Lens at Two Weeks and Four Weeks Completed
  29. N/A A Comparative Study of Two Daily Disposable Contact Lenses in Higher Myopia Subjects Completed
  30. N/A Bifocal Soft Contact Lenses and Their Effect on Myopia Progression in Children and Adolescents. Completed
  31. N/A Comparative Clinical Evaluation of Daily Disposable Lenses in Symptomatic Lens Wearers Completed
  32. N/A Product Feasibility of a New Silicone Hydrogel Contact Lens Completed
  33. N/A Prospective Study of an Investigational Toric Soft Contact Lens Completed
  34. N/A Evaluation of the Efficacy in Decreasing Myopia Progression of the Proposed Ophthalmic Lens Prototypes Completed
  35. N/A A Dispensing Clinical Trial of Test Contact Lens Against Marketed Contact Lens Completed
  36. N/A Clinical Performance of a New Daily Disposable Contact Lens Worn in an Established Contact Lens Wearing Population Completed
  37. N/A Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 2 Completed
  38. N/A Comparing a Monthly Replacement Lens Versus a Daily Disposable Lens Completed
  39. N/A Visual Performance Investigation of Two Toric Soft Contact Lenses Completed
  40. N/A Clinical Performance Comparison of Several Different Contact Lenses Completed
  41. N/A Effect of Contact Lenses on Tear Osmolarity in a Controlled Low Humidity Chamber Completed
  42. N/A Evaluating the Performance of Precision1 Daily Disposable Contact Lens in a Group of Heavy Digital Device Users Completed
  43. N/A Dispensing Study for a New Study Lens Completed
  44. N/A Performance Evaluation of Daily Disposable Contact Lenses in Habitual Lens Wearers Who Use Digital Devices Frequently Completed

Showing the 50 most-cited and recently-updated of 299 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Eye-transcutaneous electrical acupoint stimulation reduced myopia incidence in children aged 6 to 12 years compared with sham stimulation
Anesthesiology & Pain Medicine RCT
Eye-transcutaneous electrical acupoint stimulation reduced myopia incidence in children aged 6 to 12 years compared with sham stimulation New device slows nearsightedness in kids without surgery or drops
This multicenter randomized clinical trial enrolled 680 children aged 6 to 12 years with cycloplegic spherical equivalent refraction between…
A new mask that uses gentle electricity can slow nearsightedness in kids and reduce the need for strong glasses
May 1, 2026
Narrative review identifies emerging associations between gut microbiota and pediatric eye conditions
Ophthalmology Sys. Review
Narrative review identifies emerging associations between gut microbiota and pediatric eye conditions Early gut bugs may shape your child's eye health for life
This narrative review examines associations between gut microbiota dysbiosis and pediatric ophthalmic conditions including myopia and allerg…
New research suggests that the tiny bugs living in a child's gut could be the hidden reason behind their eye problems.
Frontiers Apr 28, 2026
Repeated red light therapy reduces axial length elongation in premyopic children over 24 months
Pediatrics RCT
Repeated red light therapy reduces axial length elongation in premyopic children over 24 months Red Light Therapy Slows Nearsightedness in Kids, But Rebound Risk Found
This randomized controlled trial included 108 premyopic children followed for 24.0 months to assess sustained efficacy and rebound effects.
Repeated red light therapy slowed nearsightedness in children over 2 years, but stopping treatment led to faster eye growth.
Apr 23, 2026
Systematic review and meta-analysis of atropine for myopia control in children
Pediatrics Meta-analysis
Systematic review and meta-analysis of atropine for myopia control in children Atropine Eye Drops Work Better for Some Kids Than Others, New Analysis Shows
This systematic review and meta-analysis evaluated atropine treatment in children ≤16 years with myopia across 34 RCTs.
This research confirms that atropine eye drops can slow nearsightedness in children, but how well they work depends on the dose and the chil…
Apr 23, 2026
HAL lenses associated with less myopia progression than SVL in children aged 6–12 years
Infectious Disease Cohort
HAL lenses associated with less myopia progression than SVL in children aged 6–12 years New Glasses May Slow Your Child’s Nearsightedness From Getting Worse
This retrospective cohort study in 157 school-age children with low myopia found that Highly Aspherical Lenslets (HAL) were associated with …
These new glasses can significantly slow the progression of nearsightedness in children, but age plays a major role in how well they work.
Frontiers Apr 19, 2026
HAL spectacle lenses slow myopia progression and axial elongation in Indian children and adolescents
Ophthalmology
HAL spectacle lenses slow myopia progression and axial elongation in Indian children and adolescents New Glasses May Slow Kids' Worsening Vision by 83%
A retrospective study of 372 Indian children and adolescents aged 4–16 years found that Highly Aspherical Lenslets (HAL) spectacle wear redu…
Special glasses slowed worsening nearsightedness in kids by 83%, cutting yearly vision decline from 0.72 to 0.11 diopters.
medRxiv Apr 16, 2026
SMILE shows superior refractive predictability and stability versus FS-LASIK and Trans-PRK in myopia correction
Ophthalmology Cohort
SMILE shows superior refractive predictability and stability versus FS-LASIK and Trans-PRK in myopia correction SMILE showed better predictability and stability than other laser vision correction methods in this Iraqi study
A retrospective multicenter cohort study of 919 eyes in Iraqi patients compared SMILE, FS-LASIK, and Trans-PRK for myopia correction over 1.…
SMILE laser surgery offered the most accurate and stable vision correction with the least eye dryness compared to other laser methods in thi…
Frontiers Apr 14, 2026
Wavefront-guided LASIK and PRK show high rates of 20/20 vision in patients with myopia and astigmatism
Ophthalmology
Wavefront-guided LASIK and PRK show high rates of 20/20 vision in patients with myopia and astigmatism Can Eye Surgery Trainees Really Match the Experts?
This prospective, nonrandomized clinical trial evaluated wavefront-guided laser in situ keratomileusis (WFG-LASIK) and wavefront-guided phot…
Eye surgery trainees at a California institute matched expert results, with over 90% of LASIK patients seeing 20/20 or better and no vision …
Apr 14, 2026
Meta-analysis finds outdoor activity associated with lower myopia risk in Chinese youth
Pediatrics Meta-analysis
Meta-analysis finds outdoor activity associated with lower myopia risk in Chinese youth Can more outdoor time help protect Chinese children's eyesight?
A systematic review and meta-analysis of 31 studies including 380,215 Chinese children and adolescents found greater daily outdoor activity …
Getting more than two hours of outdoor time each day lowers the risk of nearsightedness for Chinese children compared to less than an hour.
Apr 3, 2026
Outdoor time >120 min/day shows limited myopia protection in premyopic children
Pediatrics RCT
Outdoor time >120 min/day shows limited myopia protection in premyopic children Does playing outside protect kids' eyesight? For some children, it might not be enough
A post-hoc analysis of 3194 children (1369 premyopic) found hyperopic children showed reduced myopic shift with increasing outdoor time, pla…
Playing outside helps some kids avoid nearsightedness, but children already at risk need more than two hours daily to see any eye protection…
Mar 30, 2026
Meta-analysis: Myopia prevalence 30.1% in Chinese children/adolescents, peaks at 81.0% in high school
Pediatrics Meta-analysis
Meta-analysis: Myopia prevalence 30.1% in Chinese children/adolescents, peaks at 81.0% in high school Nearly 1 in 3 Chinese kids and teens has nearsightedness, with rates soaring in high school
A meta-analysis of 34 studies (n=139,765) found the pooled prevalence of myopia among Chinese children and adolescents was 30.1%.
Nearly one in three Chinese children and teens has nearsightedness, with rates soaring to 81% by high school and peaking in 2016.
Mar 30, 2026

Questions about Myopia

Do HAL spectacle lenses reduce myopia progression in Indian children?

Yes, HAL spectacle lenses significantly reduce myopia progression in Indian children, based on a real-world study showing a reduction from -0.72 D/year to -0.11 D/year.

Full answer →
Does eye-transcutaneous electrical acupoint stimulation reduce myopia incidence in children?

Yes, a 2026 randomized trial found that eye-transcutaneous electrical acupoint stimulation reduced myopia incidence in children aged 6–12 years compared to sham treatment.

Full answer →