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Meta-analysis of uncemented femoral stems shows subsidence and retroversion patterns vary by coating and surgical approachThis review examined movement in uncemented hip stems after surgery

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Key Takeaway
Note that hydroxyapatite coating and non-anterior approaches are associated with less stem migration in this meta-analysis.

This systematic review and meta-analysis synthesized data from 73 studies involving 120 cohorts and 2,970 uncemented stems to assess subsidence and retroversion patterns in patients following primary total hip replacement. The analysis covered different coating types, surgical approaches, time periods, and baseline measurement timing, with a follow-up duration of 24.0 months. The study phase was not reported, and the setting was not reported.

Key results showed subsidence of 0.29 mm at 3 months and 0.32 mm at 2 years for the overall population. Retroversion measured 0.51° at 3 months and 0.70° at 2 years. Specifically, hydroxyapatite-coated stems exhibited the least migration, with subsidence of 0.26 mm and retroversion of 0.51°. In contrast, the anterior approach was associated with more migration, showing subsidence of 1.04 mm and retroversion of 1.52°.

The authors did not report adverse events, serious adverse events, discontinuations, or tolerability. No limitations were explicitly listed in the source text, and funding or conflicts of interest were not reported. The practice relevance was not reported, and causality was not established. Given the observational nature of the included studies, causal language should be avoided when interpreting these findings.

This systematic review and meta-analysis looked at how uncemented femoral stems move inside the hip after primary total hip replacement surgery. The team combined data from 73 different studies covering 120 cohorts and 2,970 stems to see how these implants settle over time. They measured two main types of movement: subsidence, which is how far the stem sinks into the bone, and retroversion, which is how the stem rotates.

The results showed that stems generally moved a small amount. At three months, the average movement was about 0.29 millimeters, increasing slightly to 0.32 millimeters by two years. Stems with a hydroxyapatite coating tended to move the least, while those inserted through an anterior approach moved more than others.

The study did not report any safety concerns, adverse events, or reasons for stopping the use of these stems. However, because the data came from many different studies with varying methods, the findings should be viewed as a general overview rather than a strict rule for choosing implants. Readers should discuss these general trends with their surgeon to understand what might apply to their specific situation.

What this means for you:
This large review shows small movement in uncemented hip stems, with some approaches moving more than others.

Study Details

Study typeMeta analysis
EvidenceLevel 1
Follow-up24.0 mo
PublishedApr 2026
View Original Abstract ↓
BACKGROUND AND PURPOSE: We conducted a systematic review and meta-analysis of radiostereometric analysis studies of primary uncemented femoral stems to investigate their subsidence and retroversion patterns and the migration patterns according to implant, patient, and study characteristics. METHODS:  A systematic search of PubMed, Web of Science, Cochrane, and Embase databases to identify all radiostereometric analysis studies on femoral stem migration following primary uncemented total hip replacement was performed. Clinical studies with 2 or more postoperative radiostereometric measurements within 2 years were included. Subsidence and retroversion at 6 weeks, 3 and 6 months, 1, 2, 5, and 10 years were included for analysis. Extracted implant characteristics included implant design, coating, and surgical approach. Data was analyzed using a random effects model. RESULTS:  73 studies on 120 cohorts and 2,970 uncemented stems were included. 119 cohorts reported on subsidence and 91 on retroversion. The pooled subsidence at 3 months was 0.29 mm (95% confidence interval [CI] 0.19-0.39) and 0.32 mm (CI 0.21-0.43) at 2 years. The pooled retroversion at 3 months was 0.51° (CI 0.33-0.70) and 0.70° (CI 0.48-0.93) at 2 years. Hydroxyapatite-coated stems showed the least migration (subsidence 0.26 mm; CI 0.13-0.40; retroversion 0.51°; CI 0.22-0.80) among different coating types. The anterior approach showed more migration (subsidence 1.04 mm, CI 0.53-1.55; retroversion 1.52°, CI 1.08-1.95) than other surgical approaches. CONCLUSION:  Our study shows that most subsidence and retroversion of uncemented femoral stems occurs during the first 3 months. Stabilization of subsidence occurred after 3 months, and retroversion stabilized after 2 years. Migration patterns differ based on stem type, coating, surgical approach, the time period when inclusion started, and timing of baseline measurement.
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