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Narrative review on fusion space concept in colorectal cancer surgery

Narrative review on fusion space concept in colorectal cancer surgery
Photo by Navy Medicine / Unsplash
Key Takeaway
Consider the fusion space concept as a useful surgical framework in colorectal cancer, noting limited evidence.

This is a narrative review that synthesizes the concept of fusion space in colorectal cancer surgery. The authors argue that the fusion space concept appears to be the most useful in surgical practice and has histological justification. The review is based on personal experience and a literature review, not on a primary trial.

The authors note confusion in nomenclature and different terminologies for the same fascia as key limitations. No pooled effect sizes or quantitative outcomes are reported, as this is a qualitative synthesis. The scope is limited to discussing the utility of the concept rather than presenting new data.

Practice relevance is restrained to the observation that the fusion space concept seems useful in surgical practice. The review does not report a study population, intervention, comparator, or adverse events. Gaps include the lack of standardized terminology and the absence of prospective validation.

The authors acknowledge that the conclusions are based on personal experience and a literature review, which limits generalizability. Clinicians should interpret the findings as a conceptual framework rather than an evidence-based guideline.

Study Details

Study typeSystematic review
EvidenceLevel 1
PublishedMay 2026
View Original Abstract ↓
Colorectal surgery has entered the era of membrane anatomy. Total mesorectal excision (TME) and complete mesocolic excision (CME) can significantly improve the 5-year survival rate of patients with colorectal cancer. The complete excision of the mesentery is of great significance for the prognosis of patients with colorectal cancer, and the radical evaluation of colorectal cancer is based on the integrity of the mesentery of the resected gross specimen. However, in right colon cancer surgery, there are still significant controversies and uncertainties in the understanding of the abdominal fascial system and surgical plane, such as Toldt's fascia and Fredet's fascia. This situation is further aggravated by the confusion in nomenclature. Since the same fascia often has different terminologies, which hinders academic communication, Since the same fascia often has different terminologies, which hinders academic communication, we conducted a narrative review of the right colon fascia system based on our personal experience and a literature review. We discovered that although the current terminology remains non-uniform, the concept of fusion space seems to be the most useful in surgical practice and has histological justification.
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