Colorectal Cancer

All Colorectal Cancer Articles

• Sex and gender-tailored screening strategies aim to address disparities in colorectal cancer detection and participation
• AI-assisted colonoscopy modestly boosts diminutive polyp detection but not larger polyps
• Gut microbiota influence innate immune signaling and promote colibactin-associated mutational signatures in colorectal cancer
• Physical exercise during neoadjuvant chemotherapy does not significantly improve pathologic complete response in solid tumors
• SCRT plus ICI associated with higher CR and pCR rates than LCRT in rectal cancer
• Patient navigation and mailed FIT outreach significantly increase colorectal cancer screening uptake
• Impact of RAS and BRAF Mutation Status on Immune Checkpoint Inhibitor Efficacy
• Tumor immune microenvironment heterogeneity between thyroid and colorectal cancer drives distinct immune evasion mechanisms
• Adherence to clinical practice guidelines improves survival for Stage II and III colon cancer
• Pharmacokinetically guided 5-fluorouracil dosing reduces severe toxicity and improves response rates in colorectal cancer
• Endoscopic techniques like ESD and EMR offer distinct advantages for early colon cancer management
• Evaluating High-Dose Vitamin D3 Supplementation in Metastatic Colorectal Cancer Treatment Regimens
• Huangqi Guizhi Wuwu Decoction reduces grade 2 or higher OIPN from 38.6% to 21.3%
• Doublet-LC TNT improves 3-year DFS to 74.8% compared to 66.0% in high-risk rectal cancer
• Impact of Visceral Obesity on Surgical Outcomes in Colorectal Cancer Resection
• Multimodal preoperative prehabilitation improves 6-minute walk distance in patients with colorectal cancer
• PET/CT Matches MRI Sensitivity but Boosts Specificity in Rectal Cancer
• Preoperative nutritional management and micronutrient supplementation show mixed results for colorectal cancer patients
• Node-RADS demonstrates high diagnostic accuracy for lymph node metastasis in rectal cancer patients
• KRAS G12C inhibitors may remodel immunosuppressive tumor microenvironments into immunostimulatory states in KRAS-mutant tumors
• Tumor-informed ctDNA assays show 88% sensitivity for minimal residual disease detection in colorectal cancer
• S100A8/A9 promotes tumor microenvironment remodeling and serves as a potential therapeutic target in colorectal cancer
• High NLRP-3 Expression Linked to Poor Survival in Solid Cancers
• 14-3-3 proteins function as potential but unvalidated biomarkers and therapeutic targets in colorectal cancer
• COVID-19 pandemic associated with lower screening participation and higher mortality in colorectal cancer patients
• Immune checkpoint inhibitors in rectal cancer: balancing anti-tumor effects against ICI-associated colorectal injury
• Deep learning models achieve 0.979 AUC for colorectal cancer detection in histopathological whole-slide images
• Obesity increases colorectal cancer risk while normal weight is associated with lower risk
• Berberine trial protocol aims to assess 2-year DFS in stage IIIB, IIIC colorectal cancer
• Robotic low anterior resection reduces conversion rates but increases operative time compared to laparoscopic surgery
• Patient-led home-based follow-up reduces hospital contacts by 38% in colorectal cancer survivors
• Laparoscopic-endoscopic cooperative full-thickness resection achieves pT3 excision with no recurrence at 21 months
• Ultra-processed food intake correlates with 12% higher risk of digestive system cancer
• Endoscopic submucosal dissection successfully resects a large circumferential lesion with concurrent schistosomal colopathy
• AXIN2 mutations link oligodontia and colorectal polyposis while epidemiological evidence for tooth agenesis remains inconsistent
• MRI-based radiomics models predict tumor budding grade in rectal cancer with 0.88 AUC
• PCE with indigo carmine increases adenoma detection rate to 51.5% compared to 34.5% for WLE
• Mepilex Lite and indomethacin suppositories for anal canal skin radiation dermatitis trial planned
• Fecal microbiota transplantation may modulate tumor microenvironment and enhance immunotherapy responses in several cancers
• Higher tolerance of ambiguity correlates with higher perceived benefit in colorectal cancer screening
• FIT positivity and neoplasia detection rates peak in the first round of screening programs
• Terminal ileal intubation provides a 0.28% diagnostic yield for clinically significant pathology in asymptomatic patients
• Pelvic peritoneum closure reduces risk of severe postoperative complications in rectal cancer patients
• Early postoperative chemotherapy reduces risk of death in patients with colorectal cancer
• Total neoadjuvant therapy improves disease-free survival and doubles pCR in rectal cancer
• Transanal transection and single-stapled anastomosis reduces anastomotic leakage risk in rectal cancer surgery
• Elevated IGF-I levels correlate with increased risk of colorectal adenoma and colorectal cancer
• R0 resection status serves as the principal prognostic determinant for oncological outcomes in re-recurrent rectal cancer
• ctDNA and immune profiling offer a pathway toward individualized treatment for recurrent colorectal cancer
• First-line immune checkpoint inhibitor therapy improves progression-free survival and overall survival in MSI-H/dMMR mCRC
• Immune checkpoint inhibitor regimens for colorectal cancer increase risk of endocrine adverse events
• Robustly generalizable gut microbiome signatures are identified in patients with colorectal cancer regardless of age
• High tumour-associated neutrophils at the invasive margin are associated with improved overall survival
• Enhanced communication using behavioral economics principles did not significantly increase FIT test completion rates
• Sugar sweetened beverages and orange juice are associated with increased risk of several cancer types
• Intraoperative indocyanine green fluorescence angiography improves bowel perfusion assessment in colorectal anastomosis surgery
• Antibiotic exposure is associated with an 18.7% higher risk of gastrointestinal cancers
• Gut microbiome biomarkers show AUROC of 0.89 for differentiating colorectal cancer from controls
• Preoperative inflammatory and nutritional markers are associated with increased postoperative pulmonary risk in gastrointestinal cancers
• Traditional Chinese medicine may modulate immune resistance barriers in microsatellite-stable colorectal cancer
• Twenty-two factors across five ecological levels are significantly associated with fear of cancer recurrence
• Persistent descending mesocolon increases operative time and conversion rates in colorectal cancer surgery
• Multiple clinical and perioperative factors are significantly associated with postoperative abdominal infection in colorectal cancer patients
• Nanomedicine delivery systems may enhance immunotherapy efficacy in colorectal cancer
• Mendelian Randomization Evaluates IL-6 Inhibition Effects on Hepatocellular and Colorectal Cancer Risk
• Enteral immunonutrition reduces infectious complications in patients undergoing surgery for colorectal cancer
• Epigallocatechin-3-gallate shows positive therapeutic effects on various digestive system diseases in animal models
• Artificial intelligence as a mechanistic microscope and digital twin in colorectal cancer faces generalizability and regulatory validation limitations
• Screening and management strategies for stigma in patients with colorectal cancer and stomas require clinically meaningful guidance
• Oxaliplatin addition to rectal cancer chemoradiation improves tumor regression
• Systematic review shows robotic colorectal surgery lowers CRP and complications versus laparoscopy in adult patients
• Robotic TME reduces CRM positivity and three-year recurrence in mid or low rectal cancer
• Fecal DNA testing improved colorectal cancer screening rates compared to immunochemical testing in primary care
• Metabolic syndrome linked to higher risk of several obesity-related cancers and worse colorectal cancer survival
• 27648 patients shows robotic TME improves specimen quality and margin safety for rectal cancer cases
• Microbiome and metabolite markers may enhance colorectal cancer detection and therapeutic guidance strategies
• Narrative review links gut microbial metabolites to colorectal cancer mechanisms
• Multicomponent intervention with mailed FIT and navigation increased colorectal cancer screening uptake in Federally Qualified Health Centers
• PD-1/PD-L1 inhibitors improve response in dMMR/MSI-H metastatic colorectal cancer
• Narrative review discusses colorectal cancer metastasis patterns with immune checkpoint inhibitors and targeted therapies
• Postoperative exercise interventions shorten intestinal recovery time in colorectal cancer surgery
• Narrative review on immune microenvironment evolution in serrated neoplasia and colorectal cancer
• Review examines mRNA vaccines versus traditional platforms for colorectal cancer
• Meta-analysis of home-based exercise for colorectal cancer reports reduced anxiety and fatigue with low certainty evidence
• Review of gut microbiota and colorectal cancer highlights unresolved causality and clinical translation challenges
• Narrative review covers hepatocellular carcinoma, colorectal cancer, glioblastoma, breast cancer, pancreatic cancer, and non-small cell lung cancer
• Tislelizumab plus chemotherapy and radiotherapy yields 89.1% 3-year disease-free survival in pMMR/MSS locally advanced rectal cancer
• Text reminders and letters increased FIT completion in overdue colorectal cancer screening patients
• Avelumab plus cetuximab versus cetuximab alone in metastatic colorectal cancer patients
• Preoperative symbiotic supplementation alters gut microbiota in colorectal cancer patients
• TaTME shows lower conversion rates with similar short-term safety compared to LapTME for low rectal cancer
• Educational programs improve self-care values in ostomized colorectal cancer patients
• Systematic review and meta-analysis identifies factors influencing quality of life in colorectal cancer survivors
• Narrative review explores colorectal cancer mutations and tumor microenvironment interactions for TASIN-1
• Neoadjuvant mFOLFOXIRI plus bevacizumab reduces peritoneal tumor burden in colorectal cancer patients
• Systematic review and meta-analysis of robotic versus laparoscopic surgery for rectal cancer
• Narrative review suggests CXCR4 antagonists may target metastatic colorectal cancer via the CXCL12/CXCR4 axis
• Modified Banxia Xiexin Decoction plus chemotherapy shows favorable trends in advanced colorectal cancer
• Colonoscopic Surveillance in Lynch Syndrome Linked to Lower Mortality but Not Reduced Cancer Incidence
• Review of combination strategies for digestive system tumors including gastric and colorectal cancer
• Electroacupuncture Shortens Time to First Defecation in Colorectal Cancer Surgery Patients
• Thunder-fire moxibustion may reduce fatigue in colorectal cancer patients undergoing chemotherapy
• Tumor debulking plus chemotherapy did not improve overall survival in multiorgan metastatic colorectal cancer patients
• Perioperative Propranolol and Etodolac Safety and 8-Year Survival in Cancer Patients
• SCOPE platform predicts outcomes for metastatic colorectal and pancreatic cancers using organoid screening
• Narrative review examines ulcerative colitis and colorectal cancer risk
• Meta-analysis of 7,750 saliva samples validates non-invasive disease prediction models for nasopharyngeal carcinoma, colorectal cancer, and PLHIV
• Sequential cetuximab-bevacizumab vs bevacizumab-EGFR mAb shows no DDC difference in metastatic CRC
• Aspirin and NSAIDs show little benefit for colorectal cancer prevention within 15 years but increase bleeding risk
• Robotic simultaneous resection for synchronous colorectal cancer and liver metastases shows feasibility and safety in a meta-analysis
• Network meta-analysis shows image-enhanced endoscopy methods improve adenoma detection rates compared to high-definition white light imaging in colorectal lesion screening
• Neoadjuvant CAPOX chemotherapy alone showed comparable survival to chemoradiotherapy in locally advanced rectal cancer with uninvolved mesorectal fascia
• Trifluridine/tipiracil plus irinotecan and bevacizumab in metastatic colorectal cancer resistant to prior chemotherapy
• Immunonutrition supplementation significantly shortened time to first flatus in colorectal cancer surgery patients
• Cognitive-behavioral sleep intervention with nutritional support improves sleep, survival in rectal cancer surgery patients
• Intratumoral H101 plus total neoadjuvant therapy yields pathologic complete response in one patient with metachronous locally advanced rectal cancer
• Network meta-analysis ranks exercise types for colorectal cancer survivors post-resection based on specific outcomes
• Meta-analysis links higher BMI to increased early-onset colorectal cancer risk
• Dynamic ctDNA monitoring during neoadjuvant chemotherapy identifies high-risk rectal cancer patients
• Prehabilitation improves functional capacity and reduces severe complications in elective colorectal cancer surgery
• Nurse-led music intervention shows preliminary benefit for cognitive impairment in colorectal cancer patients
• Computational framework reconstructs multidimensional clinical profiles from published Kaplan-Meier images