The FDA has approved a new drug called Siliq (brodalumab) for adults with moderate to severe plaque psoriasis. Plaque psoriasis is a skin condition that causes red, scaly patches. Siliq is for patients who have tried other treatments like systemic therapy or phototherapy but did not get enough relief or stopped responding.
Siliq works by blocking a protein in the body that causes inflammation. In clinical studies, patients taking Siliq had clearer skin and fewer psoriasis symptoms after 12 weeks compared to those on a placebo. This approval provides a new option for people who have not had success with other medicines.
However, Siliq has a boxed warning about an increased risk of suicidal thoughts and behavior. Patients and doctors should watch for any changes in mood or behavior. It is important to discuss your medical history and any mental health concerns with your healthcare provider before starting Siliq.
This approval does not mean Siliq is right for everyone. Talk to your doctor to see if Siliq could be a good choice for you. Your doctor can help you weigh the benefits and risks based on your personal health situation.