Can high-dose iron improve health for people on peritoneal dialysis?

Chronic kidney disease is a serious issue, impacting about 3.5 million adults in the UK. For those with end-stage kidney disease, peritoneal dialysis is a lifeline, but it often comes with the challenge of anemia. This trial aims to find out if high-dose intravenous iron is more effective than low-dose iron or oral iron for improving health in these patients. Over a year, participants will be monitored for their anemia response, symptoms of kidney disease, quality of life, and even how well they can walk. The study will also look at how often blood transfusions are needed and whether oral iron users require intravenous iron. By understanding these factors, the trial hopes to identify the best treatment options for those undergoing peritoneal dialysis, ultimately aiming to enhance their overall well-being.