This study examined whether a specific breathing and training method could change brain structure in people with mood disorders. The participants had major depressive disorder or bipolar disorder and were currently in remission. They were part of a larger trial called ALTIBRAIN.
After three weeks, the group received daily sessions involving low oxygen levels and cognitive exercises. The other group received standard treatment as usual. Researchers then used advanced MRI scans to look for changes in the prefrontal cortex and hippocampus.
The results showed no significant differences between the groups. Neither the oxygen training nor the standard treatment changed the brain scan measurements. Additionally, the study did not find links between these brain changes and improvements in thinking skills.
Because the study was small and only followed participants for one month, the results are uncertain. The specific brain scans used might not have detected all possible changes. Readers should not assume this method works for everyone, and more research is required before any medical recommendations can be made.