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Thoracoscopic resection provides favorable outcomes for pediatric patients with extralobar pulmonary sequestration complicated by torsionRare Lung Condition in Children: Torsion and Infarction Cases Reviewed

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Key Takeaway
Note that thoracoscopic resection offers a favorable prognosis for pediatric extralobar pulmonary sequestration cases.

This literature review and case series explores the clinical presentation and surgical management of pediatric patients with extralobar pulmonary sequestration (ELS) complicated by torsion and infarction. The authors synthesize evidence from 3 reported cases and 24 additional cases identified in a literature review to evaluate outcomes following thoracoscopic resection.

In the primary case series, all 3 patients were confirmed via pathological examination to have pulmonary sequestration with hemorrhagic necrosis. Imaging findings included 2 patients suspected of intrathoracic soft-tissue masses and 1 patient diagnosed with pulmonary sequestration. Clinical presentations varied between abdominal pain alone and combined abdominal and chest pain. The review suggests that thoracoscopic surgery is an effective approach for these complications.

A primary limitation noted by the authors is the small sample size of only 3 cases in the series. While the findings suggest a favorable prognosis for pediatric patients with ELS complicated by torsion, the limited data volume necessitates cautious interpretation. Clinical application should consider the specific presentation of torsion and infarction before surgical planning.

A rare condition called extralobar pulmonary sequestration (ELS) can twist and cut off its own blood supply, causing pain and tissue death. A new report from Shanghai Children's Hospital describes three children with this complication. Two had abdominal and chest pain; one had only abdominal pain. CT scans suggested masses in two cases, but all three were correctly diagnosed after surgery.

The report also reviewed 24 similar cases in children from medical literature. All three children in the case series had surgery to remove the affected lung tissue. After the operation, doctors confirmed the tissue had hemorrhagic necrosis, meaning it had died due to lack of blood flow.

This is a small study, so the findings are limited. The report does not compare surgery to other treatments or track long-term outcomes. No safety issues were noted, but the study was too small to draw firm conclusions about risks.

For parents and doctors, the key message is that ELS with torsion is rare but can be treated with surgery. If a child has unexplained abdominal or chest pain, this condition is one possibility to consider. Always consult a pediatric specialist for diagnosis and treatment.

What this means for you:
Surgery can treat rare twisted lung tissue in children, but this is based on a small case series.

Common questions

What is extralobar pulmonary sequestration?

It is a rare birth defect where a piece of lung tissue develops outside the normal lung and has its own blood supply. This tissue does not function like normal lung and can sometimes twist, cutting off its blood flow.

What are the symptoms of a twisted lung sequestration?

In this case series, children had abdominal and chest pain, or just abdominal pain. Symptoms can be vague, so imaging like CT scans is needed to diagnose the condition.

How is this condition treated?

The treatment described in this report is thoracoscopic surgery to remove the abnormal lung tissue. All three children in the series had surgery, and the removed tissue showed signs of tissue death from lack of blood flow.

Is this condition common?

No, it is very rare. The report only found 24 total pediatric cases in the medical literature, plus the 3 new cases. This is not a common cause of chest or abdominal pain in children.

Study Details

Study typeSystematic review
EvidenceLevel 1
PublishedJul 2026
View Original Abstract ↓
BackgroundExtralobar pulmonary sequestration (ELS) is a rare congenital pulmonary malformation, and reports of ELS complicated by torsion and infarction are exceedingly uncommon. Here, we report three pediatric cases of ELS complicated by torsion and infarction, aiming to enhance clinical awareness and understanding of this condition.MethodsUsing the keywords “extralobar pulmonary sequestration, torsion, infarction, thoracoscopic, chest pain, abdominal pain, children”, we conducted a comprehensive literature review of all studies related to ELS with torsion in children from database inception to December 2025. We identified 16 articles describing ELS with torsion, comprising a total of 24 reported pediatric cases of pulmonary sequestration complicated by torsion.ResultsBetween May 2022 and November 2025, three children with ELS complicated by torsion and infarction were treated at Shanghai Children's Hospital. Two patients presented primarily with abdominal pain and chest pain, while one patient presented with abdominal pain alone. Contrast-enhanced chest computed tomography (CT) was performed in all cases: two patients were suspected of having intrathoracic soft-tissue masses, and one patient was diagnosed with pulmonary sequestration. All patients subsequently underwent thoracoscopic resection of the pulmonary sequestration. Postoperative pathological examination confirmed pulmonary sequestration with hemorrhagic necrosis in all three cases.ConclusionsPulmonary sequestration with torsion should be considered in the differential diagnosis of patients presenting with chest/abdominal pain accompanied by an intrathoracic soft-tissue mass. With the continuous advancement of minimally invasive techniques, thoracoscopic surgery offers a favorable prognosis for pediatric patients with pulmonary sequestration complicated by torsion and infarction.
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