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Robotic-assisted treadmill training improves walking measures in children with spastic diplegic cerebral palsy

Robotic-assisted treadmill training improves walking measures in children with spastic diplegic cere…
Photo by Sam Moghadam / Unsplash
Key Takeaway
Consider robotic-assisted treadmill training as adjunct therapy for walking in spastic diplegia, but interpret early efficacy data cautiously.

In a randomized controlled trial, 40 children aged 6 to 11 years with spastic diplegic cerebral palsy who could ambulate but had abnormal gait kinematics were studied. The intervention group received robotic-assisted treadmill gait training using Lokomat in addition to a regular physical therapy program based on the neurodevelopmental approach, while the comparator group received only the regular physical therapy program.

The group receiving the combined robotic training and therapy showed statistically significant improvement (p < 0.05) in all measured variables: walking speed, step length, step symmetry, and 6-minute walk test performance. Post-treatment mean values of all measured variables also showed significant differences between groups (p < 0.05), favoring the group that received robotic-assisted training.

Safety and tolerability data were not reported in the abstract, and the study did not report effect sizes, confidence intervals, or absolute numbers for the improvements. The clinical significance of the statistically significant findings remains unclear without these quantitative measures. While the RCT design suggests causal inference is possible, the abstract does not specify primary versus secondary outcomes or adjustments for multiple comparisons.

For clinical practice, these findings from a single RCT with modest sample size suggest robotic-assisted treadmill gait training could be considered as an additional therapeutic modality to improve walking performance in children with spastic diplegia. However, clinicians should interpret these results cautiously given the lack of reported safety data, effect sizes, and information about the sustainability of improvements.

Study Details

Study typeRct
EvidenceLevel 2
PublishedApr 2026
View Original Abstract ↓
BACKGROUND AND PURPOSE: Children diagnosed with diplegic cerebral palsy frequently experience gait difficulties that can significantly affect their independence and quality of life. The development of advanced technologies presents opportunities to enhance their walking abilities and overall functional performance. The purpose of this study was to determine how children with spastic diplegia performed when walking after completing robotic-assisted treadmill gait training (RATGT). METHODS: Forty children with spastic diplegia participated in this randomized controlled trial. Their ages ranged from 6 to 11 years, and they were able to ambulate and displayed abnormal gait kinematics. They were randomly classified into two groups of equal number; the control group (A) received a regular physical therapy program based on the neurodevelopmental approach, while the study group (B) received RATGT using Lokomat in addition to the regular physical therapy program. Biodex Gait Trainer II was used to assess walking speed, step length, step symmetry, and the 6-min walk test to assess walking capacity for each group before and after the treatment program. RESULTS: There was statistically significant improvement of all measured variables in group B (p < 0.05), with significant difference between groups when comparing post-treatment mean values of all measured variables (p < 0.05). DISCUSSION: These findings suggested that RATGT could be used as an additional therapeutic modality to improve walking performance in children with spastic diplegia. TRIAL REGISTRATION: Clinical trial registration number from the Pan African Clinical Trials Registry (PACTR) - PACTR202503598420671.
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