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Managed transition increased AMHS care receipt and appropriate transitions at 15 months in youth with IQ ≤70.

Managed transition increased AMHS care receipt and appropriate transitions at 15 months in youth wit…
Photo by Dmytro Vynohradov / Unsplash
Key Takeaway
Consider managed transition programs for youth with IQ ≤70 near service transition, noting higher AMHS care receipt at 15 months.

This study was a secondary analysis of a cluster randomised clinical trial involving 793 participants receiving child and adolescent mental health services (CAMHS) care. The population consisted of individuals with an IQ of 70 or less who were within one year of their service transition boundary. The trial was conducted across 40 CAMHS sites in eight countries. The intervention was a managed transition (MT) program consisting of training, identification, and assessment of transition readiness and appropriateness. The comparator was usual care (UC). The primary outcome was whether participants were receiving care from adult mental health services (AMHS) at 15 months follow-up.

At 15 months, 24.9% of participants in the MT group were receiving care from AMHS compared to 14.2% in the UC group. In absolute numbers, this represented 241 participants in the MT group versus 552 in the UC group. The difference was statistically significant with a p-value of 0.002. Regarding appropriate transitions, 32.3% of the MT group achieved this outcome versus 16.4% in the UC group, with a p-value less than 0.001.

Safety and tolerability data were not reported in this analysis. No adverse events, serious adverse events, discontinuations, or specific tolerability metrics were provided. The study limitations include the fact that this is a secondary analysis of a larger trial, and no specific limitations were listed in the provided data. Funding or conflicts of interest were not reported. The certainty of the evidence is not explicitly stated in the input data.

The practice relevance suggests that clinicians and services should consider incorporating managed transition into routine clinical care. However, given the lack of reported safety data and the specific population of youth with intellectual disabilities near transition age, broader application requires further investigation. The findings indicate a potential benefit for structured transition programs in this specific demographic.

Study Details

Study typeRct
Sample sizen = 793
EvidenceLevel 2
Follow-up12.0 mo
PublishedApr 2026
View Original Abstract ↓
BACKGROUND: Transition from Child and Adolescent Mental Health Services (CAMHS) to Adult Mental Health Services (AMHS) is poorly managed, with discontinuity of care commonplace, leading to poorer outcomes, while evidence-based interventions to improve transition are scarce. This study is a secondary analysis of the MILESTONE trial, aiming to determine whether managed transition increases the proportion of young people who appropriately transition from CAMHS to AMHS. METHODS: The MILESTONE trial was a multicenter, two-arm, cluster-randomized controlled trial across eight countries at 40 CAMHS sites to compare usual care (UC) to managed transition (MT). MT consisted of training, identification, and assessment of transition readiness and appropriateness. Eligible participants were receiving CAMHS care, IQ ⩾ 70 and within 1 year of their service transition boundary. CAMHS sites were randomized 2:1 between UC and MT. The main outcome was whether participants were receiving care from AMHS at 15 months follow up. RESULTS: The MILESTONE study included 793 participants, 552 receiving UC and 241 receiving MT. In the MT group, 24.9% transitioned to AMHS at 15 months compared to 14.2% in the UC group ( = 0.002), and appropriate transitions (in those with a need for transition at baseline or ongoing clinical need at 15 months) were 32.3% in the MT group compared to 16.4% in the UC group ( < 0.001). CONCLUSIONS: A higher proportion of the MT group transitioned to AMHS at 15 months, and there was a higher proportion of appropriate transitions compared to UC. Clinicians and services should consider the incorporation of MT into routine clinical care.
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