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Repeated red light therapy reduces axial length elongation in premyopic children over 24 monthsRed Light Therapy Slows Nearsightedness in Kids, But Rebound Risk Found

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Key Takeaway
Note rebound axial elongation after cessation of repeated red light therapy in premyopic children.

This randomized controlled trial enrolled 108 premyopic children with cycloplegia spherical equivalent refraction between -0.50 and +0.75 D. Participants underwent 24.0 months of follow-up to evaluate sustained efficacy and rebound effects of the therapy. The study was conducted in an unspecified setting.

The intervention involved repeated red light therapy administered two times per day for 3 min per session, with at least 4-hour interval. The RRLT group showed significantly smaller axial length elongation compared with controls, with absolute numbers of 0.26 mm versus 0.43 mm. Spherical equivalent refraction progression was also reduced in the RRLT group at -0.21 D compared with -0.66 D in controls. Both outcomes indicate a reduction in myopia-related changes during the study period.

Safety data regarding adverse events, serious adverse events, and discontinuations were not reported. Subfoveal choroidal thickness thinning was significantly less in the RRLT group at -2.44 µm compared with -44.12 µm in controls. Washout subgroup analysis indicated faster axial length elongation and more choroidal thinning after cessation. Limitations were not reported in the study documentation. No adverse events were documented in the provided text.

Practice relevance was not reported. Clinicians should note the rebound effects in the washout subgroup when considering long-term management strategies for premyopia. Further research is needed to confirm long-term safety. Current evidence does not support definitive practice changes.

If your child is on the verge of becoming nearsighted, a new study suggests a surprising tool might help: red light. Researchers tested repeated low-level red light therapy (RRLT) in 108 children with premyopia—eyes that are still normal but heading toward nearsightedness. Kids in the treatment group received two 3-minute sessions of red light each day, at least 4 hours apart. Over 24 months, their eyes lengthened less and their prescription changed more slowly compared to a control group. For example, the treated group's eyes grew only 0.26 mm on average, versus 0.43 mm in controls. Their nearsightedness progressed by -0.21 diopters, compared to -0.66 diopters in controls. The therapy also preserved the thickness of a layer behind the retina called the choroid, which thins in nearsighted eyes. But here's the catch: when some kids stopped the therapy, their eyes started growing faster again, and the choroid thinned more than in controls. This suggests the benefits may not last without continued treatment. The study is small and didn't report on side effects, so more research is needed. Still, for parents looking for ways to slow nearsightedness in kids, this early evidence points to a potential new option—with a warning about rebound.

What this means for you:
Red light therapy slowed nearsightedness progression in children, but stopping treatment may cause rapid eye growth.

Study Details

Study typeRct
EvidenceLevel 2
Follow-up24.0 mo
PublishedApr 2026
View Original Abstract ↓
BACKGROUND: To evaluate the long-term prevention effectiveness and rebound effect of repeated red light therapy (RRLT) in children with premyopia over 2 years. METHODS: A total of 108 premyopic children (cycloplegia spherical equivalent refraction (SER): -0.50 to +0.75 D) were enrolled and followed for 24 months. Participants were randomly assigned to the RRLT or control groups. The RRLT was administered two times per day for 3 min per session, with at least 4-hour interval. At the beginning of the second year, participants receiving RRLT were further randomised into continued treatment and washout subgroups. Axial length (AL), SER and subfoveal choroidal thickness (SChT) were measured. RESULTS: Over 2 years, the RRLT group showed significantly smaller AL elongation (0.26 mm; 95% CI 0.18 to 0.35 mm) and SER progression (-0.21 D; 95% CI -0.35 to -0.08 D) compared with the controls (AL: 0.43 mm; 95% CI 0.36 to 0.49 mm; SER: -0.66 D; 95% CI -0.79 to -0.52 D). The RRLT group also demonstrated significantly less SChT thinning (-2.44 µm; 95% CI -16.11 to 11.23 µm) than the controls (-44.12 µm; 95% CI -53.05 to -35.19 µm). After RRLT cessation in the second year, the washout subgroup exhibited significantly faster AL elongation and more SChT thinning than the controls, with no significant difference in SER progression. CONCLUSIONS: The 2-year RRLT intervention effectively retarded AL elongation and SER progression in premyopic children by 0.17 mm and -0.45 D, respectively. Notably, a significant rebound effect was observed in AL growth following 1-year RRLT cessation.
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