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Systematic review and meta-analysis compares ESIN versus plating for pediatric femoral shaft fractures

Systematic review and meta-analysis compares ESIN versus plating for pediatric femoral shaft fractur…
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Key Takeaway
Note that safety and outcome data were not reported for ESIN versus plating in pediatric femoral fractures.

This systematic review and meta-analysis focuses on the comparison between elastic stable intramedullary nailing (ESIN) and plating for the treatment of diaphyseal femoral fractures in patients aged 18 years or younger. The scope of the review encompasses this specific fracture type within the pediatric population.

Key details regarding the sample size and the clinical setting were not reported in the source material. Furthermore, the primary outcome of interest was not reported, and no secondary outcomes were specified in the provided data. Consequently, specific pooled effect sizes or quantitative comparisons between the two fixation methods were not available for synthesis.

Safety data, including adverse events, serious adverse events, discontinuations, and tolerability, were not reported. The authors did not identify specific limitations beyond the absence of these data points. Funding sources and potential conflicts of interest were not reported. The practice relevance of these findings was not explicitly stated in the source text.

Given the lack of reported outcomes and safety data, the clinical utility of this review is limited to establishing the scope of the comparison rather than providing definitive efficacy or safety conclusions.

Study Details

Study typeMeta analysis
EvidenceLevel 1
PublishedApr 2026
View Original Abstract ↓
IntroductionFemoral shaft fractures are the most common pediatric femoral injury, accounting for 64%–68% of cases in children under 18 years. While younger children are usually treated non-surgically, older children often require fixation. Elastic stable intramedullary nailing (ESIN) and plating are the two main surgical options, but the optimal method remains debated.MethodsThis systematic review and meta-analysis followed PRISMA guidelines and was registered in PROSPERO. Medline/PubMed, ScienceDirect, Scopus, and Embase were searched for randomized controlled trials (RCTs) comparing ESIN and plating in patients ≤18 years with diaphyseal femoral fractures. Two reviewers independently extracted data, and study quality was assessed using the Cochrane Risk of Bias 2 tool. Meta-analyses were performed in RevMan 5.4.1 using random-effects models with significance set at P 
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