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High and low intensity resistance training both acutely lower blood pressure in treated hypertension

High and low intensity resistance training both acutely lower blood pressure in treated hypertension
Photo by omid armin / Unsplash
Key Takeaway
Consider that both high and low intensity resistance training may acutely lower BP in treated hypertension.

This randomized clinical trial examined acute cardiac autonomic responses and blood pressure changes following resistance training in 31 adults with pharmacologically treated hypertension. Participants completed a single session of either high intensity resistance training (80% of 1RM) or low intensity training (40% of 1RM), with both protocols matched for total training volume. Measurements were taken before and immediately after exercise.

Both training intensities produced significant reductions in blood pressure, though exact numerical values were not reported. No significant interaction between training intensity and any measured variable was observed (p > 0.05). Cardiac parasympathetic indices showed significant reductions, with the low intensity protocol demonstrating a more pronounced cardiac autonomic response characterized by greater vagal withdrawal.

Correlation analyses indicated a positive association between changes in the V1% heart rate variability index and blood pressure reductions, and a negative correlation between low frequency heart rate variability and blood pressure. Safety and tolerability data were not reported. Key limitations include the small sample size of 31 participants, acute measurements only, and the correlational nature of the autonomic findings, which preclude causal interpretation. The study provides preliminary evidence that both high and low intensity resistance training can acutely lower blood pressure in this population, but long-term effects and clinical significance remain uncertain.

Study Details

Study typeRct
Sample sizen = 31
EvidenceLevel 2
PublishedApr 2026
View Original Abstract ↓
This study aimed to assess the acute cardiac autonomic responses to high and low intensity resistance training and their association with post exercise hypotension in adults with pharmacologically treated hypertension. This randomized clinical trial included 31 participants with pharmacologically treated hypertension. The effects of two resistance training sessions performed at high intensity (80% of 1RM) and low intensity (40% of 1RM), matched for total training volume, were compared. Blood pressure and heart rate variability were measured before and after exercise. Significance level was set at 5%. No significant interaction was observed for any of the variables (p > 0.05). Both intensities produced significant reductions in blood pressure and in cardiac parasympathetic indices. During the high intensity session, ΔV1% heart rate variability index was positively correlated with blood pressure reductions. During the low intensity session, low frequency was negatively correlated with blood pressure. In conclusion, both high and low intensity RT elicited acute hypotensive effects, with a more pronounced cardiac autonomic response characterized by greater vagal withdrawal observed for the low intensity training protocol. Furthermore, changes in indices related to cardiac sympathetic modulation and greater decreases in cardiac parasympathetic modulation were associated with a greater post exercise hypotensive response.
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