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Resistance Training May Boost Working Memory and Cognitive Flexibility in Older AdultsResistance training improves memory and flexibility in older adults

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Key Takeaway
Resistance training may improve working memory and cognitive flexibility in older adults, but evidence certainty is low.

This meta-analysis examined whether resistance training improves executive functions in community-dwelling older adults aged 60 and older without cognitive impairment. Twenty-two trials met inclusion criteria, with 17 studies contributing to the meta-analysis.

Working memory improved significantly with resistance training versus control conditions (standardized mean difference, 0.30; 95% CI, 0.02-0.59; P =.04). Cognitive flexibility also improved significantly (standardized mean difference, -0.50; 95% CI, -0.88 to -0.12; P =.009). However, no significant effects were observed for inhibitory control.

When resistance training was compared with other exercise interventions, no significant differences emerged for working memory or cognitive flexibility, suggesting benefits may not be unique to resistance training.

The overall certainty of evidence was low, with high risk of bias across studies and heterogeneity in intervention protocols. Adverse events, discontinuations, and tolerability were not reported, and funding or conflicts of interest were not described.

Clinicians should interpret these findings cautiously. Resistance training may contribute to improvements in some executive function domains, particularly working memory and cognitive flexibility, but the low certainty of evidence and high risk of bias limit definitive conclusions.

Staying sharp as we age is a major concern for many people. New research looked at how resistance training, or strength training, affects the brains of adults aged 60 and older who do not have cognitive impairment. The goal was to see if lifting weights or using resistance could improve executive functions, which are the mental skills we use to manage tasks and focus.

The analysis of 17 studies found that resistance training significantly improved working memory and cognitive flexibility compared to doing nothing or other types of exercise. However, the training did not show a significant effect on inhibitory control, which is the ability to ignore distractions. While the results are promising for specific types of mental agility, the evidence is currently considered low certainty because the studies varied a lot in how they were designed.

Because the methods used in these studies were not all the same, we should be cautious about how much we can conclude. While the data suggests that strength training can help with memory and mental flexibility, it is not a guaranteed fix for every type of cognitive challenge. Talk with your doctor to see how these types of exercises might fit into your personal health plan.

What this means for you:
Resistance training may improve working memory and mental flexibility in adults over 60.

Common questions

Does resistance training help with memory in older adults?

Yes, the study found that resistance training significantly improved working memory in adults aged 60 and older compared to control conditions. However, it did not show a significant difference when compared to other types of exercise interventions.

What other mental skills are affected by strength training?

The research showed that resistance training improved cognitive flexibility, which is the ability to switch between tasks. It did not show any significant effects on inhibitory control, which is the ability to ignore distractions or impulses.

How reliable are these findings for older adults?

The evidence is currently considered low certainty. This is because the studies included in the analysis had a high risk of bias and used very different types of training protocols, so the results should be interpreted with caution.

Study Details

Study typeMeta analysis
EvidenceLevel 1
Follow-up720.0 mo
PublishedOct 2026
View Original Abstract ↓
OBJECTIVE: To systematically evaluate the effectiveness of resistance training interventions on executive functions in community-dwelling older adults free of cognitive impairment. DESIGN: Systematic review and meta-analysis. SETTING AND PARTICIPANTS: Community-dwelling adults aged 60 years and older without cognitive impairment. METHODS: A systematic search was conducted in PubMed, Web of Science, SCOPUS, and EMBASE for randomized controlled trials of resistance exercise in adults aged 60 or more up to February 17, 2025. Outcomes included inhibitory control, working memory, and cognitive flexibility. Risk of bias (RoB) was assessed using the Cochrane RoB 2.0 tool, and evidence quality was graded with Grading of Recommendations Assessment, Development, and Evaluation. Findings were synthesized descriptively and narratively, and a meta-analysis was conducted using Review Manager 5.4. RESULTS: Twenty-two trials met the inclusion criteria. The meta-analysis, which ultimately included 17 studies, revealed that RT significantly improved working memory compared with control conditions (standardized mean difference, 0.30; 95% CI, 0.02-0.59; P = .04) and cognitive flexibility (standardized mean difference, -0.50; 95% CI, -0.88 to -0.12; P = .009), whereas no significant effects were observed for inhibitory control. However, when RT was compared with other exercise interventions, no significant between-group differences were identified for working memory, inhibitory control, or cognitive flexibility. CONCLUSIONS AND IMPLICATIONS: RT may contribute to improvements in some domains of EF in older adults, particularly working memory and cognitive flexibility. However, these findings should be interpreted cautiously because of the heterogeneity of intervention protocols, the overall low certainty of evidence, and the high RoB across studies. Further high-quality trials with standardized training parameters are required to clarify the potential cognitive effects of RT and its comparative effectiveness relative to other exercise modalities.
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