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Manual therapy and therapeutic exercise reduce pain intensity in patients with temporomandibular disordersHands-On Therapy May Ease Jaw Pain Better Than Splints

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Key Takeaway
Consider manual therapy and therapeutic exercise as first-line interventions for reducing pain in patients with TMD.

This systematic review and network meta-analysis evaluates the efficacy of manual therapy (MT) and therapeutic exercise (TE) for managing pain in individuals with temporomandibular disorders (TMDs). The analysis included data from 1,540 patients to compare MT and TE against no treatment, placebo, occlusal splints, and instrumental physiotherapy.

The authors synthesized evidence showing that MT and TE were more effective than control groups in most studies. Furthermore, multimodal treatments were identified as the most effective approach for pain reduction. Specifically, a combination of dry needling and manual therapy appeared to be the most effective approach among the analyzed interventions.

Limitations noted by the authors include significant variability in study quality. Because of this variability, the certainty of these findings is limited, and more high-quality research is needed to confirm the observed effects. Clinical application suggests that MT and TE are effective first-line interventions for TMD pain before considering more invasive treatments.

How this fits prior evidence

This finding extends the existing evidence for non-invasive management of temporomandibular disorders. While prior coverage established that extracorporeal shock wave therapy significantly reduces pain intensity in patients with temporomandibular disorders, this meta-analysis adds evidence for manual therapy and therapeutic exercise as effective first-line interventions for pain reduction.

If you have temporomandibular disorders, or TMDs, you know the drill: jaw pain that makes eating, talking, or just existing uncomfortable. A new review of 1,540 people with TMDs asked a simple question. What actually helps? The answer points away from the usual first stop, a bite splint, and toward hands-on care. Manual therapy, where a therapist works the jaw and surrounding muscles with their hands, and therapeutic exercise both beat no treatment, placebo, splints, and instrumental physiotherapy in most of the studies. The review also found that combining treatments worked better than any single approach. And the strongest signal came from pairing dry needling, a technique that uses thin needles to release tight muscle knots, with manual therapy. But there is a catch. The studies varied in quality, so the results are not rock solid. The review authors say we need better research to confirm what they found. They also note that manual therapy and exercise should be tried before more invasive options. If you are weighing treatment choices for jaw pain, talk with your doctor about what is right for you.

What this means for you:
Hands-on therapy and exercise may ease jaw pain better than splints, but study quality varies.

Common questions

What is manual therapy for jaw pain?

Manual therapy is hands-on treatment where a therapist uses their hands to stretch and mobilize the jaw and surrounding muscles. In this review of 1,540 people with temporomandibular disorders, manual therapy and therapeutic exercise were more effective than no treatment, placebo, splints, or instrumental physiotherapy in most studies.

Is dry needling safe for TMDs?

The review did not report any safety information about dry needling or other treatments. It only looked at pain intensity. If you are considering dry needling, talk with your doctor about whether it is safe for you.

How does manual therapy compare to a bite splint?

In this review, manual therapy and exercise were more effective than occlusal splints for reducing pain in people with temporomandibular disorders. The review authors suggest these hands-on approaches should be tried before more invasive treatments.

What is the best treatment for jaw pain?

The review found that combining treatments worked better than any single approach. The strongest result came from pairing dry needling with manual therapy, but the authors say this finding needs more research to confirm because study quality varied.

Study Details

Study typeMeta analysis
EvidenceLevel 1
PublishedOct 2026
View Original Abstract ↓
Background: Temporomandibular disorders (TMDs) are common conditions in the general population. Several therapeutic approaches are available, but there is no consensus on the most effective, particularly in physiotherapy. Objectives: To assess the efficacy of manual therapy (MT) and therapeutic exercise (TE) in reducing pain in patients with TMDs. Methods: Four databases (MEDLINE, PEDro, EMBASE, CINAHL) were searched up to March 2025. We included randomized controlled trials (RCTs) evaluating the effects of MT and/or TE in individuals with TMDs, compared to any other rehabilitation treatment, with pain intensity as the primary outcome. The methodological quality was assessed using the PEDro scale. A network meta-analysis was performed to compare the effectiveness of different rehabilitative approaches. Results: 25 RCTs for a total of 1,540 people were included. The main comparisons were: MT and/or TE vs no treatment or placebo, occlusal splint, and instrumental physiotherapy. In most studies, MT and TE were more effective than controls in reducing pain. However, the network meta-analysis indicated that multimodal treatments were the most effective. The methodological quality of the included studies ranged from 3 to 9 points. Conclusion: MT and TE are effective strategies for reducing pain in subjects with TMDs and should be used as first-line interventions before more invasive treatments; the combination of dry needling and manual therapy appears to be the most effective approach. Nonetheless, the variability in study quality suggests that further high-quality research is needed to confirm these findings.
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