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Digital intervention shows no significant weight loss difference compared to standard advice at 6 monthsTailored digital tools show promise for long term weight loss

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Key Takeaway
Note that tailored digital interventions did not significantly outperform standard advice for weight loss at 6 or 12 months.

This randomized controlled trial enrolled 288 adults with overweight and obesity to evaluate a 90-day digital intervention using Ecological Momentary Assessments to tailor weight loss behavior. The control group received non-tailored weight loss advice via generic emails and an eBook. The primary outcome was body weight measured at 6 and 12 months.

At 6 months, no significant difference in mean weight loss was observed between the intervention group (n=145) and the control group (n=143), with a mean difference of 0.78 kg (p =.232). At 12 months, the intervention group showed a higher mean weight loss than the control group, but the difference of 2.05 kg was not statistically significant (p =.088).

Safety data were not reported, though the study noted a higher than expected dropout rate due to the COVID-19 pandemic. The study's limitations include these high attrition rates, which complicated face-to-face assessments. While the 12-month data suggest a trend toward better weight loss maintenance in the tailored group, the results are not statistically significant. Clinical application is currently limited by these findings.

How this fits prior evidence

How this fits prior evidence: This study addresses a gap in digital intervention strategies for weight management in adults with overweight and obesity. While previous coverage noted that exercise training prevents 45.7% of fat-free mass loss during calorie restriction, this trial focuses on the efficacy of tailored digital interventions versus standard advice. The results do not currently provide a statistically significant basis to favor tailored digital interventions over standard advice for weight loss in this population.

Losing weight and keeping it off is a constant challenge for many people living with obesity. Researchers wanted to see if a personalized digital tool could make a difference compared to standard weight loss advice sent through emails and an eBook.

For 90 days, one group used a digital system that tracked their daily behaviors to create a custom plan. The other group received general advice. At the six-month mark, both groups saw similar results in weight loss. However, at the one-year mark, those using the tailored digital tool lost more weight than those receiving the standard advice.

While the difference at one year was not statistically significant, the trend was promising for long term weight maintenance. The study did face some hurdles, including a higher than expected number of people dropping out because the pandemic made in person checkups difficult. These results suggest that personalized digital tools could be a helpful way to support people on their weight loss journeys.

What this means for you:
Tailored digital tools showed a trend toward better weight loss at one year compared to standard advice.

Common questions

How did the tailored digital program work?

The program lasted 90 days and used something called Ecological Momentary Assessments. This means the system tracked daily behaviors to identify what was working for the person. This information was then used to create a tailored plan specifically for their weight loss goals.

Was the tailored program better than standard advice?

At six months, there was no significant difference in weight loss between the two groups. However, at the 12-month mark, the group using the tailored digital tool lost more weight than the group receiving standard advice, though this specific difference was not statistically significant.

Were there any safety concerns or issues with the study?

The study did not report any specific adverse events or safety concerns. However, there was a higher than expected dropout rate because the pandemic made it difficult for participants to attend face-to-face assessments.

Study Details

Study typeRct
EvidenceLevel 2
Follow-up12.0 mo
PublishedSep 2026
View Original Abstract ↓
OBJECTIVE: This study aimed to determine the effectiveness and cost-effectiveness of the program, which tailors support to an individual's weight loss and weight loss maintenance determinants among adults with overweight and obesity. METHOD: We conducted a randomized controlled trial with a nested interrupted time series within-person design. Participants ( = 288) were randomized to the digital intervention ( = 145) or a control group ( = 143). Intervention participants completed 90 days of Ecological Momentary Assessments, which were used to identify behavioral determinants to tailor an intervention. Control participants received nontailored weight loss advice via generic emails and eBook. Body weight (the primary outcome), blood pressure, and % body fat (secondary outcomes) measured at 3, 6 and 12 months were restructured into change of baseline scores and analyzed using multilevel regression analysis, with the three time points nested within subjects. RESULTS: Findings revealed no significant difference in mean weight loss between groups at 6 months, controlled for baseline (primary outcome; mean difference = 0.78 kg), (1, 175) = 1.44, = .232. Intervention participants had higher weight loss at 12 months than control participants (mean difference = 2.05 kg), (1, 108) = 2.96, = .088); however, the difference was not statistically significant. CONCLUSIONS: The results showed promising trends for the intervention group in weight loss maintenance measured at 12 months. The dropout rate was higher than expected, as the intervention was delivered during the COVID-19 pandemic making face-to-face assessments difficult. (PsycInfo Database Record (c) 2026 APA, all rights reserved).
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