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Patient Questions

Real questions from health communities, answered with cited research from PubMed and Vellito's article corpus. Plain language, no medical advice. How this works.

What is the Systemic Immune-Inflammation Index for coronary heart disease?

The Systemic Immune-Inflammation Index (SII) is a blood test marker that combines platelet, neutrophil, and lymphocyte counts to measure inflammation. Higher SII levels are…

OB/GYN & Women's Health

Are women with Polycystic Ovary Syndrome more likely to have autoimmune thyroiditis if they are obese?

Yes, a retrospective study found that obese women with PCOS have a higher prevalence of autoimmune thyroiditis (23.6%) compared to non-obese women with PCOS (18.6%).

Pediatrics

Are there differences in newborn growth measurements for babies exposed to opioids in the womb?

Yes, babies exposed to opioids in the womb tend to have lower birth weight and smaller head circumference, with differences depending on the specific medication used.

Can TP53 or PTEN mutations be found in ovarian cancer samples?

Yes, TP53 and PTEN mutations are found in ovarian cancer samples, with TP53 in 68% and PTEN in 47% of cases in one study.

Oncology

How does having inherited cancer susceptibility change ovarian cancer prevention options?

Inherited cancer susceptibility, especially BRCA1/2 mutations, expands prevention options to include risk-reducing salpingo-oophorectomy, chemoprevention with oral…

Did ovarian cancer diagnoses go down during the COVID-19 pandemic years?

Yes, ovarian cancer diagnoses decreased during the early COVID-19 pandemic years, as shown by a Swiss study that found fewer new cases in 2020 and 2021 compared to 2019.

Oncology

What are the limitations of using olaparib and bevacizumab for ovarian cancer?

Olaparib plus bevacizumab is most effective in HRD-positive ovarian cancer; in HR-proficient tumors, benefit is limited, and resistance, side effects, and cost are key limitations.

Diabetes & Endocrinology

Can lifestyle interventions lead to sustained remission of prediabetes in overweight adults?

Yes, lifestyle interventions can lead to sustained prediabetes remission in about 12% of overweight adults, with those achieving remission having a 68% lower risk of developing…

Which local or regional technique reduces Postoperative Pain the most after upper GI surgery?

Epidural analgesia provides the greatest reduction in postoperative pain at 24 hours after open upper GI surgery, according to a network meta-analysis.

How much lower is the diabetes risk if prediabetes reverts to normal blood sugar?

Reversing prediabetes to normal blood sugar is linked to a 68% lower risk of developing type 2 diabetes, based on a large meta-analysis.

OB/GYN & Women's Health

Does preoperative pain education help reduce Postoperative Pain after a cesarean section?

Yes, preoperative pain education can reduce postoperative pain after cesarean section, based on a 2024 study showing lower pain scores and less analgesic use.

Is prediabetes linked to higher risks of frailty in adults aged 50 or older?

Yes, prediabetes is linked to a higher risk of frailty and functional decline in adults aged 50 or older, according to a large pooled analysis of longitudinal studies.

Does semaglutide improve quality of life for adults with schizophrenia and prediabetes?

Yes, semaglutide improves physical quality of life in adults with schizophrenia and prediabetes, but not mental quality of life, based on a 30-week trial.

What are the diet management experiences of Swedish women living with prediabetes?

Swedish women with prediabetes experience tension between health goals and emotional needs around food, feeling pressured to manage their own and their family's eating habits.

Neurology

Is replacing plasma with young donor blood safe for people with mild cognitive impairment?

A small pilot study found that replacing plasma with young donor blood is feasible and appears safe in the short term for people with mild cognitive impairment, but larger…

Cardiology

Do beta-blockers reduce my risk of death if my heart function is normal after MI?

For patients with normal heart function after MI, beta-blockers do not appear to reduce the risk of death or recurrent heart attack based on recent large trials.

Can brain shrinkage patterns predict when mild cognitive impairment turns into Alzheimer's disease?

Yes, specific brain shrinkage patterns, especially in the precuneus and fusiform gyrus, can help predict progression from mild cognitive impairment to Alzheimer's disease, but…

Cardiology

How do artificial intelligence tools compare to doctors for predicting heart attack biomarkers?

AI tools can match or slightly outperform doctors in predicting heart attack biomarkers, but most studies lack real-world validation.

Does losing the sense of smell mean mild cognitive impairment will become dementia?

Losing your sense of smell is a warning sign that mild cognitive impairment may progress to dementia, but it does not guarantee it will happen.

Cardiology

Does having a specific type of myocardial injury increase my risk of future heart events?

Yes, the type of myocardial injury matters: type 1 MI carries the highest risk of future heart events, but type 2 MI and acute/chronic myocardial injury also increase risk…

Gastroenterology

Are there new drugs for Crohn's Disease approved by the FDA?

Yes, the FDA has approved newer drugs for Crohn's disease, including Stelara (ustekinumab) and Hadlima (adalimumab), and selective IL-23 inhibitors are emerging as promising…

Gastroenterology

Do the new biomarkers in the study help diagnose Crohn's Disease?

The study identified three biomarkers (ARHGEF3, S100A8, RHOU) that show high diagnostic accuracy for ulcerative colitis, but their ability to diagnose Crohn's disease…

Gastroenterology

How does gut bacteria diversity in Crohn's Disease compare to healthy people?

People with Crohn's disease typically have lower gut bacteria diversity and an altered microbial community compared to healthy individuals.

Infectious Disease

How sensitive and specific is the Pluslife RHAM test for detecting monkeypox?

The Pluslife RHAM test detects monkeypox with 94.2% sensitivity and 100% specificity when compared to standard PCR methods.

How this works

We pull real patient questions from public Reddit health communities (r/AskDocs, r/diabetes, r/menopause, etc.). Each question is rewritten into a generic medical question (no personal details), then answered by an AI using only cited sources from Vellito's article database and PubMed. A second AI independently scores each answer for accuracy and citation fidelity before publication. Answers below the safety threshold or touching emergency, dosing, or pediatric topics are queued for human review and never auto-published.

This is not medical advice. Always speak with your own doctor before making decisions about your health.