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Case Report and Review of Recurrent Dysplasia Epiphysealis Hemimelica After Surgery

Case Report and Review of Recurrent Dysplasia Epiphysealis Hemimelica After Surgery
Photo by Risto Kokkonen / Unsplash
Key Takeaway
Consider that recurrence of Dysplasia Epiphysealis Hemimelica may occur after surgery, but evidence is from a single case.

This article is a case report combined with a review of the literature on Dysplasia Epiphysealis Hemimelica (DEH), focusing on recurrence after surgical intervention. The authors present a single patient who experienced recurrence of DEH 3 months following initial surgery, with symptoms including increased pain, limping, and significant ankle stiffness compared to the initial presentation. Histopathological examination of the recurrent lesion revealed immature fibrocartilaginous tissue, nodular proliferation of collagenous fibrous tissue, cartilage fragments, and foreign-body granulomatous reaction.

The authors note that recurrence in DEH is closely linked to incomplete surgical excision and the patient's age. Based on this single case and review, they propose a postoperative follow-up protocol to mitigate the risk of recurrence. However, the evidence is limited by the nature of a single case report, and generalizability beyond this case is not possible.

No adverse events or safety data were reported. The practice relevance is limited to suggesting a follow-up protocol, but clinicians should recognize that these findings are derived from a single case and literature review, not from a controlled study.

Study Details

Study typeSystematic review
EvidenceLevel 1
PublishedMay 2026
View Original Abstract ↓
This paper presents a case of Dysplasia Epiphysealis Hemimelica that recurred 3 months following the initial surgical intervention. The recurrence was notably characterized by increased pain, limping, and significant ankle stiffness compared to the initial presentation. Histopathological analysis of the recurrence revealed immature fibrocartilaginous tissue, nodular proliferation of collagenous fibrous tissue, and cartilage fragments, accompanied by a foreign-body granulomatous reaction. A review of the literature suggests that recurrence of this condition is closely linked to incomplete surgical excision and the patient’s age. Based on these insights, we propose a postoperative follow-up protocol to mitigate the risk of recurrence.
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