Centurion active fluidics linked to lower intraoperative pain and corneal thickness versus gravity-based fluidics in cataract
This prospective cohort study included 130 patients (65 per group) undergoing phacoemulsification for age-related cataract. The intervention utilized the Centurion Vision System with active fluidics targeting an intraocular pressure of 30 mmHg. The comparator group received the Stellaris Elite System with gravity-based fluidics at approximately 62 mmHg. Follow-up duration was 1 month.
Primary outcomes assessed intraoperative discomfort via supplemental anesthesia requirement and patient-reported pain scores on a 0–10 numerical rating scale. Fewer patients in the Active Fluidics Group required supplemental anesthesia, with absolute numbers of 3.1% versus 13.8% (relative risk 0.22; 95% CI 0.05–0.98; p = 0.028). Median pain scores were 1 versus 3 (p < 0.001). Day-1 central corneal thickness increase was smaller with active fluidics, showing a mean difference of −18.4 μm (28.4 vs. 46.8 μm; 95% CI −26.1 to −10.7; p < 0.001).
Endothelial cell density loss and final visual acuity were comparable between groups, though specific numbers were not reported. No intraoperative complications occurred during the procedure. Serious adverse events, discontinuations, and tolerability data were not reported.
The study design is observational, limiting causal inference regarding the fluidic systems. Limitations and practice relevance were not reported in the source material. Clinicians should interpret these findings cautiously within the context of the specific surgical settings and equipment used.
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