Deep Learning Reconstruction EOB-MRI detects more small low-signal lesions than standard non-DL MRI in 53 patients
This prospective, single-center study included 53 patients who underwent EOB-MRI during the hepatobiliary phase (HBP). The intervention was Deep Learning Reconstruction (DL Recon) EOB-MRI, compared against traditional Gd-EOB-DTPA-enhanced liver MRI (Standard Non-DL, HR Non-DL). The primary outcome was the detection of focal liver lesions (FLLs).
Regarding small low-signal lesions measuring 5–10 mm, the Standard DL group showed significantly more lesions than the Standard Non-DL group with a P value of 0.030. For high-signal lesions, no differences were observed across groups, with all other P values greater than 0.05. Similarly, no significant differences were found between groups for large low-signal lesions greater than 10 mm, where P was greater than 0.05.
Safety and tolerability data were not reported in this study. The total number of high-signal lesions showed a difference between Standard DL and Standard Non-DL with a P value of 0.048, though absolute numbers were not reported. Because this was a single-center study with a small sample size of 53 patients, the findings require cautious interpretation regarding broader clinical application.