ACIP Recommends JYNNEOS Vaccine for Adults at Risk During Mpox Outbreaks
Health Panel Recommends Mpox Vaccine for At-Risk Adults During Outbreaks
A 2023 ACIP recommendation report advises use of the JYNNEOS vaccine for persons aged 18 years and older at risk for mpox during an outbreak…
U.S. health experts now recommend the JYNNEOS vaccine for adults at risk of mpox during outbreaks to help protect public health.
Reference-free computational method identifies spike-specific BCR sequences with over 90% purity in mRNA vaccinees
New computational method identifies vaccine-specific immune cells with high precision
An observational methodological study in healthy SARS-CoV-2 mRNA vaccine recipients evaluated a reference-free computational framework (LM-Q…
Researchers developed a computational method to identify immune cells that respond specifically to vaccines.
Pilot study finds cytokine differences between anti-NMDAR and viral encephalitis
Could a simple blood test help tell two dangerous brain inflammations apart?
A retrospective pilot cohort of 45 patients found significant alterations in CSF/serum albumin ratio, IL-4, and IL-17A levels between anti-N…
A simple blood test might help doctors quickly tell apart two dangerous brain inflammations by spotting unique protein patterns in patients.
ACIP recommends additional updated COVID-19 vaccine dose for adults 65 and older
Should older adults get another COVID-19 shot? Health advisors say yes
The Advisory Committee on Immunization Practices (ACIP) has issued a recommendation for all adults aged 65 years and older in the United Sta…
National health experts now recommend that everyone age 65 and older get an extra updated COVID-19 vaccine shot to stay protected.
Tofacitinib used in single case of steroid-refractory multi-organ immune-related adverse events
Single case shows tofacitinib may help with severe immune side effects from cancer immunotherapy
A case report describes a 75-year-old female with colon cancer who developed steroid-refractory immune checkpoint inhibitor-associated myoca…
A single case shows tofacitinib helped a cancer patient recover from severe heart inflammation that steroids could not fix, though infection…
Mobile App Plus Standard Care Shows Mixed Results for Asthma Control in Malaysian Adults
Can a phone app help adults with asthma breathe easier?
A 6-month RCT of 162 adult asthma outpatients in Malaysia compared the CareAide® mobile app plus standard care to standard care alone.
A phone app helped some Malaysian adults with asthma feel more in control of their breathing after six months of use alongside standard care…
Earlier menarche linked to macrosomia risk; dietary patterns may modify association in Chinese cohort
Could a woman's first period timing affect her baby's birth weight?
A prospective cohort study of 2,554 Chinese women found earlier age at menarche (before age 13) was associated with higher odds of macrosomi…
Women whose first period started before age 13 had nearly double the odds of having a larger-than-average baby compared to those who started…
Gut microbiome interventions show conceptual promise for allergic rhinitis but clinical application remains constrained
Can fixing your gut help with seasonal allergies? The science isn't ready yet
A narrative mini-review examining gut microbiome-based interventions for allergic rhinitis found these therapies represent a promising conce…
Gut microbiome therapies for seasonal allergies show promise, but doctors lack standard tests to measure results or confirm long-term safety…
Review explores mitochondrial transfer mechanisms in immune microenvironment remodeling across diseases
Review explores how cells share mitochondria to influence immune responses in disease
A systematic review summarizes emerging evidence on intercellular mitochondrial transfer mechanisms in inflammation, cancer, and autoimmune …
Cells swap energy factories to reshape immune responses in cancer, inflammation, and autoimmune diseases, offering new ways to target these …
Review suggests T cell epitope vaccines may help control dengue infection and modulate ADE risk
Could targeting T cells lead to a safer dengue vaccine?
A systematic review examines research on dengue virus T cell epitope-mediated immunity and antibody-dependent enhancement (ADE).
A new dengue vaccine strategy targeting T cells could help control the virus and reduce the risk of severe disease from antibody-dependent e…
Elevated neutrophil-to-lymphocyte ratio correlates with higher mortality in rheumatoid arthritis
Higher blood cell ratio linked to increased mortality risk in rheumatoid arthritis patients
A meta-analysis of seven observational studies in patients with rheumatoid arthritis found elevated neutrophil-to-lymphocyte ratio (NLR) was…
A high blood cell ratio linked to severe inflammation raises the risk of death by 70% for people with rheumatoid arthritis.
Phase 3 trial compares switch to doravirine/islatravir versus continuing bictegravir/FTC/TAF in HIV-1
Phase 3 trial compares two HIV drug regimens for people already virologically suppressed
A phase 3 randomized controlled trial enrolled 643 virologically suppressed adults with HIV-1 to compare switching to doravirine/islatravir …
People with HIV already on effective treatment can safely switch to a new two-drug pill without losing virus control, according to a complet…