Systematic review finds neoantigen vaccines show recurrence-free survival benefit in adjuvant melanoma
Can a custom vaccine help stop melanoma from coming back?
A systematic review of clinical trial data found that customised neoantigen vaccines, specifically mRNA-4157 from the KEYNOTE-942 trial, dem…
A custom mRNA vaccine linked to longer recurrence-free survival for melanoma patients after surgery, though it works best against 'hot' tumo…
Meta-analysis finds 2.31% EoE incidence with food allergen immunotherapy, none with aeroallergen SLIT
Study finds link between food allergy treatment and rare swallowing condition
A systematic review and meta-analysis of 17 studies in patients receiving allergen immunotherapy found the incidence of confirmed eosinophil…
Food allergy treatment linked to rare swallowing condition in 2.3% of patients receiving food desensitization, while airborne treatments sho…
Remote digital asthma management shows modest quality of life and lung function improvements in adults
Can asthma apps and websites help adults breathe easier?
A meta-analysis of 10 trials in adults with asthma found interactive remote digital management improved quality of life, symptom control, an…
Digital asthma tools show small lung function gains, but quality of life improvements were modest and didn't reach the threshold for patient…
Review explores ferroptosis in ocular microenvironment and potential therapeutic interventions
Could a new type of cell death be harming your eyes?
A systematic review evaluates the role of ferroptosis in ocular neuroinflammation and tissue degeneration.
Scientists are focusing on a destructive process called ferroptosis, where cells die from iron overload, as a potential driver of eye inflam…
Digital technologies in food supply chains show promise for safety and loss reduction, but nutrition evidence is limited
Digital tools show promise for food safety and waste reduction in supply chains
A scoping review of 46 studies found digital technologies like blockchain, IoT, and AI are applied primarily in storage and transportation.
Digital tools in food supply chains boost safety and cut waste, but only 6.5% of studies prove they improve the nutrition people actually ea…
Neuroimmune mechanisms may sustain urticaria pruritus and contribute to treatment resistance
Why do some hives keep itching? New research points to a brain-immune connection
A systematic review synthesizes evidence on neuro-immune interactions in urticaria, suggesting these mechanisms amplify pruritic signaling a…
Chronic hives may persist due to a brain-immune feedback loop that amplifies itching and inflammation, making some treatments less effective…
Systematic review describes polysaccharide mechanisms and structure-activity relationships for anti-cancer effects
Review explores how natural polysaccharides may work against cancer in lab studies
A systematic review summarizes preclinical research on natural polysaccharides, describing multi-target anti-cancer mechanisms including imm…
Natural plant sugars might fight cancer by boosting immune cells, triggering tumor death, and stopping blood vessel growth in lab tests.
Same-day desensitization linked to lower breakthrough reaction rate than rapid protocol in chemotherapy hypersensitivity
Can a same-day approach reduce allergic reactions during cancer treatment?
A retrospective cohort study of 120 patients with hypersensitivity reactions to platinum- or taxane-based chemotherapy compared same-day des…
A same-day desensitization approach reduced breakthrough allergic reactions to 15% compared to 24% for patients receiving rapid protocols du…
Plasma GPX activity negatively correlates with non-EoE atopic disease in pediatric subjects only
Early study finds link between blood enzyme and childhood allergies, but not EoE
An exploratory study in pediatric and adult subjects found plasma glutathione peroxidase (GPX) activity negatively correlated with non-EoE a…
Lower blood enzyme levels linked to childhood allergies, but not eosinophilic esophagitis, in an early study.
Dietary zinc supplementation alleviates allergic rhinitis in rats via gut-nasal axis
Could zinc help with allergies? A rat study suggests a possible gut-nose connection
A preclinical animal study in rats found dietary zinc supplementation may alleviate allergic rhinitis, especially at 150 ppm, through mechan…
A rat study suggests zinc supplements might help seasonal allergies by balancing gut bacteria and reducing inflammation in the nose.
Asia-Pacific experts propose clinical remission definition and lung function goals for severe asthma
What does it mean to beat severe asthma in Asia? Experts propose new goals
A position statement by Asia-Pacific experts reviewed severe asthma management challenges in the region.
Experts redefine severe asthma success in Asia by prioritizing symptom control and stability over impossible lung function recovery.
Systematic review suggests biologics may improve outcomes in chronic rhinosinusitis with nasal polyps
Can newer biologic drugs help people with chronic sinus polyps breathe easier?
A systematic review of clinical trials and real-world data in patients with chronic rhinosinusitis with nasal polyps found biologics may enh…
Newer biologic drugs can improve quality of life for chronic sinus polyps patients, reduce steroid use, and lower the need for sinus surgery…