Spatio-temporal graph neural networks improve prediction accuracy and interpretability for regional disease risk modeling
New computer models improve accuracy for predicting regional disease risks
This systematic review of 76 core studies evaluates spatio-temporal graph neural networks (ST-GNNs) and multi-source data fusion. The author…
Advanced graph neural networks are showing more promise than traditional methods for tracking and predicting where diseases might spread nex…
Remifentanil lowers maternal mean arterial pressure at intubation but may decrease 1-minute Apgar scores
Remifentanil impacts mother and baby health during emergency C-sections
This meta-analysis of randomized controlled trials evaluated remifentanil for parturients and newborns during cesarean sections under genera…
New data shows remifentanil helps stabilize a mother's blood pressure during surgery but may lower a newborn's first minute health score.
PEID reduces operative time and fluoroscopy frequency compared to PETD for L5/S1 disc herniation
Trial shows endoscopic surgery may shorten operative time for disc issues
This meta-analysis of 13 studies involving 1,059 patients compares PEID and PETD for single-level L5/S1 lumbar disc herniation. The analysis…
A new analysis suggests one type of endoscopic surgery for lumbar disc herniation may be faster and use less radiation during the procedure.
Quadratus lumborum block reduces 24-h morphine consumption by 3.19 mg in cesarean section patients
Quadratus lumborum block reduces morphine use after C section
This meta-analysis of 23 RCTs involving 1,935 patients found that quadratus lumborum block (QLB) significantly reduced 24-hour morphine cons…
A specific nerve block can lower the amount of morphine needed for pain management during and after a cesarean birth.
VR-assisted physiotherapy improves pain, function, and balance in knee osteoarthritis
Virtual reality helps manage knee osteoarthritis pain and function
This systematic review and meta-analysis found that virtual reality (VR)-assisted physiotherapy significantly improves pain, physical functi…
Using virtual reality during physical therapy can provide better pain relief and improved balance for people with knee osteoarthritis.
Percutaneous Cervical Cordotomy reduces pain and opioid consumption in patients with severe cancer pain
Procedure Shows Relief for Severe Treatment Resistant Cancer Pain
This meta-analysis of randomized controlled trials evaluates percutaneous cervical cordotomy (PCC) for managing treatment-resistant cancer p…
A surgical procedure called percutaneous cervical cordotomy may reduce severe cancer pain and lower the amount of opioids needed by patients…
Methadone shows significantly higher treatment retention than buprenorphine-naloxone in patients with Opioid Use Disorder
Methadone beats buprenorphine for opioid treatment retention
This meta-analysis of 7 randomized controlled trials involving 3622 patients found that methadone is associated with significantly higher tr…
Methadone keeps more people in opioid treatment than buprenorphine-naloxone, but the combo drug has fewer serious side effects.
Empowered Relief trial evaluates if 1-session intervention is non-inferior to 8-session CBT for chronic pain
Trial Plans to Compare Short and Long Pain Interventions
This randomized comparative effectiveness study protocol aims to evaluate the efficacy of a 1-session Empowered Relief (ER) behavioral inter…
A new trial will compare a single online session of behavioral therapy against an eight-session program for managing chronic pain.
Esketamine reduces 3-month postpartum depression incidence from 20.89% to 11.59% in primiparae
Trial shows esketamine reduces postpartum depression risk in new mothers
This randomized controlled trial of 322 primiparae found that a single dose of esketamine significantly reduced the incidence of postpartum …
A clinical trial suggests that a single dose of esketamine during C-section surgery may lower the risk of developing postpartum depression.
Nitrous oxide reduces pain and improves completion rates in office hysteroscopy
Nitrous oxide reduces pain during office hysteroscopy procedures
This single-center RCT of 214 women found that inhaled nitrous oxide significantly reduced intraprocedural pain and improved procedure compl…
Inhaled nitrous oxide significantly lowers pain and improves patient satisfaction for women undergoing office operative hysteroscopy.
Intraoperative surgeon-performed adductor canal blocks are non-inferior to anesthesiologist-performed blocks for TKA discharge
Surgeons performing nerve blocks may help patients leave hospital sooner
This randomized controlled trial of 200 patients undergoing total knee arthroplasty found no significant difference in time to discharge bet…
A new trial shows that surgeons performing specific nerve blocks for knee surgery provide similar pain relief and discharge times as anesthe…
Opioid Wizard tool increases primary care clinician confidence in screening, diagnosing, and referring patients for OUD
Digital Tool Improves Clinician Confidence in Managing Opioid Use Disorder
This secondary analysis of an RCT evaluates the Opioid Wizard clinical decision support tool's impact on primary care clinicians managing op…
A new digital decision support tool helps primary care doctors feel more confident when screening and diagnosing patients with opioid use di…