Intermittent hypoxia-hyperoxia therapy significantly improves pain and functional mobility in musculoskeletal dysfunctions
Intermittent Hypoxia Hyperoxia Therapy May Help Relieve Chronic Muscle and Joint Pain
This meta-analysis of 321 adults with musculoskeletal dysfunctions found that intermittent hypoxia-hyperoxia therapy (IHHT) significantly im…
A review of studies shows that a specific oxygen therapy can significantly reduce pain and improve daily movement for adults with muscle iss…
Tai Chi significantly reduces pain and improves functional disability in chronic non-specific low back pain
Tai Chi helps manage chronic low back pain and disability
This meta-analysis of randomized controlled trials involving 526 patients found that Tai Chi significantly reduced pain (MD -1.40) and impro…
Tai Chi may offer a safe way to reduce chronic low back pain and improve daily physical function for those living with the condition.
Mood disorders and benzodiazepine use increase risk for new persistent opioid use in postsurgical adults
Mood Disorders and Anxiety Linked to Higher Risk of Opioid Use
This meta-analysis of retrospective cohort studies identifies that mood disorders, anxiety, Medicaid enrollment, and preoperative benzodiaze…
Patients with anxiety or mood disorders may face a higher risk of developing persistent opioid use after surgery.
Tegileridine provides superior analgesic efficacy over placebo for postoperative acute pain with a favorable safety profile
Tegileridine shows promise for managing pain after surgery
This meta-analysis of 1,011 patients evaluated tegileridine for postoperative acute pain. Tegileridine significantly reduced rSPID24 and rSP…
A new medication called tegileridine may offer a way to manage severe pain after surgery with fewer side effects like nausea and vomiting.
TENS reduces pain (MD -0.82) and improves muscle strength in patients with knee osteoarthritis
TENS Therapy May Help Manage Knee Osteoarthritis Pain
This meta-analysis of 20 RCTs indicates that transcutaneous electrical nerve stimulation (TENS) significantly reduces pain and improves musc…
A review of clinical trials suggests that TENS devices can reduce pain and improve muscle strength for people with knee osteoarthritis.
Percutaneous electrolysis provides superior pain reduction compared to baseline care in lateral epicondylitis
Percutaneous electrolysis and dry needling help treat tennis elbow
This network meta-analysis of 38 RCTs evaluated percutaneous electrolysis, dry needling, platelet-rich plasma, and corticosteroid injections…
New analysis shows percutaneous electrolysis is highly effective for pain relief, while dry needling helps restore function in patients with…
Meta Analysis Evaluating Transcutaneous Auricular Vagus Nerve Stimulation for Cognitive Enhancement
Vagus nerve stimulation shows link to improved cognitive performance
New evidence suggests taVNS significantly improves executive functions and cognitive flexibility across diverse patient populations.
A large review of studies suggests that ear-based vagus nerve stimulation may improve memory, focus, and emotional regulation.
Suture-less closure may reduce pain and swelling after mandibular third molar extraction
Suture-less wound closure may reduce pain after wisdom tooth surgery
This meta-analysis of 10 RCTs compared suture-less wound closure with multiple-suture primary closure after mandibular third molar extractio…
Patients undergoing wisdom tooth surgery might experience less pain and swelling when surgeons use a suture-less method to close the wound.
Trial protocol evaluates three liposomal bupivacaine concentrations for superior trunk block in rotator cuff repair
New plan tests bupivacaine doses for rotator cuff surgery
This trial protocol describes a randomized controlled trial of 282 adult patients undergoing elective arthroscopic rotator cuff repair. The …
A new clinical trial plans to test if different concentrations of liposomal bupivacaine can reduce pain and morphine use after shoulder surg…
Repetitive transcranial magnetic stimulation may increase network flexibility to address chronic pain through triple-network interactions
New Theory Explains Why Chronic Pain Persists in the Brain
This narrative review explores a theoretical framework where chronic pain is viewed as a stable attractor configuration of the SN, DMN, and …
A new theoretical model suggests that chronic pain is caused by specific brain network patterns, which may help shape future treatments.
Peripheral nerve blocks reduce 24-hour morphine use by 16.20 mg in kidney transplant recipients
Nerve blocks cut opioid use after kidney transplant surgery
This meta-analysis of adult kidney transplant recipients found that peripheral nerve blocks (PNBs) reduced 24-hour morphine consumption by 1…
A new analysis shows nerve blocks reduce opioid use by 16 mg after kidney transplant, with no reported side effects.
Blood flow restriction exercise may reduce pain through metabolic and neurological pathways for musculoskeletal injuries
Blood Flow Restriction Exercise May Help Manage Chronic Pain
This narrative review explores the impact of blood flow restriction (BFR) exercise on pain response, muscle mass, and strength in clinical a…
Blood flow restriction training may reduce pain and build muscle mass, but specific pressures must be carefully monitored to ensure safety.