Review synthesizes rTMS and tDCS efficacy for neuropathic orofacial pain management
New Brain Stimulation Eases Worst Facial Pain
This mini-review evaluates the role of Repetitive Transcranial Magnetic Stimulation (rTMS) and Transcranial Direct Current Stimulation (tDCS…
Non-invasive brain stimulation cuts severe facial pain by up to 45% without surgery or heavy drugs, offering hope for patients suffering fro…
Systematic review of neuropathic pain trials reveals high prevalence of restrictive exclusion criteria.
The Patients Left Out of Pain Research Don't Look Like You'd Think
This systematic review and meta-analysis evaluated 161 primary clinical trial publications from 2012 to 2022 regarding treatments for neurop…
Pain trials often exclude patients with depression or other conditions, leaving out the very people who suffer most from nerve pain.
Memantine reduces opioid use but not pain in knee osteoarthritis patients after surgery
This Common Memory Drug Cuts Opioid Use After Knee Replacement
A randomized controlled trial in adults with knee osteoarthritis found memantine did not significantly lower pain scores versus placebo, but…
A drug already approved for Alzheimer's disease may help knee replacement patients rely less on opioids during recovery — even if it does no…
Mobile app engagement and perceived usefulness in adult primary care patients with chronic pain
The Pain App Most People Kept Opening
This feasibility randomized controlled trial conducted a secondary analysis of data from 49 adult primary care patients with chronic pain. T…
A mobile app for chronic pain held people's attention for weeks on average, though deeper engagement varied widely from one user to the next…
Palm stimulator and cartoon reduce pain and fear during IV catheterization in children aged 5-12
Can a simple palm stimulator or cartoon ease a child's needle pain and fear?
A single-center RCT of 90 children aged 5-12 found that both a palm stimulator and watching a cartoon significantly reduced pain and fear sc…
Simple distractions like squeezing a palm stimulator or watching cartoons significantly reduced pain and fear during IVs for children aged 5…
Review finds TCM stroke trials less likely to define primary outcomes and report safety than Western medicine trials
Review finds Chinese herbal trials for stroke often lack standard outcome measures compared to Western medicine studies
A comparative analysis of 306 RCTs in acute stroke (2020-2024) found that Chinese herbal medicine trials were less likely to define primary …
Only 10% of Chinese herbal stroke trials defined a primary outcome, compared to 46% of Western medicine studies, making direct comparisons d…
Advanced monitoring tools may aid insertion timing in painless gastroscopy compared to traditional indicators
Timing the Scope: Why Seconds Matter in Painless Endoscopy
A narrative review examined advanced monitoring tools versus traditional indicators for determining insertion timing during painless gastros…
Getting the timing right on a sedated scope insertion may lower coughing, gagging, and risk — and smarter monitors can help.
Mechanism-oriented interventions show promising results for taxane-induced neuropathic pain in breast cancer survivors.
New Hope for Breast Cancer Nerve Pain
This critical review evaluated mechanism-oriented interventions, including pharmacological treatments and neuromodulation, for taxane-induce…
Breast cancer survivors face long-term nerve pain from chemo, but new methods targeting the broken nerve machinery offer better relief witho…
Sleeve-fundoplication without gastric resection reduces GERD incidence versus sleeve gastrectomy in obese rat model
New stomach surgery stops acid burn while you lose weight
A preclinical randomized controlled trial in 24 obese rats found sleeve-fundoplication without gastric resection (SG-F) significantly reduce…
A new stomach surgery helps you lose weight without worsening acid reflux, offering a safer alternative to standard procedures that often ma…
Vonoprazan-based regimens show higher H. pylori eradication rates than rabeprazole dual therapy in Chinese cohort
A New Stomach Infection Treatment Works Where Old Ones Often Fail
A retrospective cohort study of 598 H. pylori-positive outpatients in Guizhou, China, found vonoprazan-based regimens achieved eradication r…
For millions struggling with a common and stubborn stomach bug, a new treatment approach just proved it can succeed where standard care freq…
Network meta-analysis compares 155 analgesic regimens for pain after knee and hip arthroplasty
Study Compares 155 Pain Relief Methods After Knee and Hip Replacement Surgery
A network meta-analysis of 211 RCTs involving 22,972 patients compared 155 analgesic regimens for postoperative pain after knee or hip arthr…
Patients recovering from knee or hip surgery can find which of 155 pain relief methods best controls pain and improves movement in the first…
PENG block with bupivacaine reduces early POCD incidence after hip arthroplasty in older patients
PENG block may lower confusion and pain after hip surgery in older adults
In a randomized, double-blind study of 84 older patients undergoing hip arthroplasty, ultrasound-guided PENG block with 0.25% bupivacaine re…
An ultrasound-guided PENG block lowers confusion and pain after hip surgery in older adults, helping them move earlier and use fewer painkil…