Protocol outlines non-invasive skeletal muscle assessment in adolescents with single ventricle heart disease versus matched controls
Why Muscles Matter More Than You Think
This cross-sectional protocol describes a study in adolescents aged 12–21 years with single ventricle heart disease and matched controls.
In single ventricle heart disease, leg muscles act as a second pump to move blood when the heart cannot do it alone.
AI-derived echocardiographic measurements predict outcomes in transthyretin cardiomyopathy patients
AI Echo Scan Predicts Heart Failure Risk
This retrospective study evaluated 347 patients from two ATTR-CM registries to assess the prognostic value of AI-derived echocardiographic m…
A new computer program can spot warning signs of heart trouble in ATTR-CM patients better than current methods alone.
Deep learning model predicts post-TAVR LVOTO in patients with severe aortic stenosis
An AI Spots a Hidden Heart Risk Before a Common Valve Procedure
This retrospective observational study evaluated 302 patients undergoing transcatheter aortic valve replacement for severe aortic stenosis.
A new AI tool can analyze a simple heart ultrasound to predict a risky complication after a common valve procedure, potentially making the s…
Meta-analysis finds SGLT2 inhibitors reduce mortality and hospitalization in older heart failure patients
Older Adults With Heart Failure May Gain Years From This Pill
A systematic review and meta-analysis of 20,844 patients aged 65+ with heart failure found SGLT2 inhibitors were associated with reduced all…
A pooled look at 10 studies in over 20,000 older adults shows SGLT2 inhibitors cut the risk of dying from any cause by about a fifth — and t…
Ticagrelor Not Noninferior to Prasugrel in Diabetes Patients With Multivessel CAD After PCI
New study shows ticagrelor did not beat prasugrel for heart attack prevention in diabetics
This randomized clinical trial of 1,800 patients with diabetes and multivessel coronary artery disease undergoing PCI compared ticagrelor pl…
For diabetics with heart stents, a new study found ticagrelor offered no clear advantage over prasugrel in preventing death, heart attacks, …
Adding low-dose rivaroxaban to DAPT did not significantly reduce LV thrombus in anterior STEMI patients
Adding low-dose rivaroxaban to standard heart attack drugs did not clearly prevent blood clots in the heart
This randomized clinical trial evaluated 560 patients with anterior ST-segment elevation myocardial infarction (STEMI) across 29 centers in …
Adding a low-dose blood thinner to standard heart attack drugs did not clearly prevent dangerous clots in the heart, based on a trial of 560…
Edoxaban monotherapy reduces adverse events compared to dual therapy in patients with atrial fibrillation and coronary artery disease
One Blood Thinner May Be Safer Than Two for Heart Rhythm Patients
This secondary analysis of a randomized clinical trial evaluated 1,040 patients with atrial fibrillation and stable coronary artery disease.
Taking just one blood thinner instead of two cuts the risk of death, stroke, or bleeding for heart patients with irregular rhythms.
Left bundle-branch pacing reduced death or heart failure hospitalization compared with biventricular pacing in heart failure with left bundle-branch block
Left bundle-branch pacing reduced death or hospitalization compared to biventricular pacing in heart failure patients
This randomized clinical trial enrolled 200 patients at six centers in China with heart failure, left bundle-branch block, and an LVEF of 35…
Left bundle-branch pacing cuts heart failure hospitalizations by 70% compared to standard biventricular pacing in patients with severe heart…
Conduction system pacing showed inferior outcomes compared to biventricular pacing in adults with heart failure and left bundle-branch block
New Brazil study found conduction system pacing was inferior to biventricular pacing for heart failure patients
This randomized clinical trial enrolled 173 adults with symptomatic heart failure with reduced ejection fraction and left bundle-branch bloc…
A new Brazil trial found conduction system pacing was worse than standard biventricular pacing for heart failure patients, increasing risks …
Elevated circulating Lp(a) levels associated with increased heart failure incidence in 400,631 participants
Does high Lp(a) truly raise your risk of heart failure, and what does that mean for you?
This meta-analysis of prospective cohort studies involving 400,631 participants evaluated the association between circulating Lp(a) levels a…
High levels of a specific blood protein called Lp(a) are linked to a 34% higher risk of developing heart failure, with the danger rising sha…
Intravascular imaging and FFR-guided PCI reduce major adverse cardiovascular events versus angiography
Advanced imaging and physiology guidance during heart procedures may lower event risk compared to angiography alone
A network meta-analysis of 43 RCTs involving 39,291 patients undergoing PCI found intravascular imaging (IVUS, OCT/OCTA) and fractional flow…
Advanced imaging and physiology guidance during heart procedures may lower event risk compared to angiography alone
HFpEF probability scores rule out disease but show limitations in AF and obesity phenotypes
HFpEF probability scores work well for typical cases but struggle with atrial fibrillation and obesity
This systematic review evaluated the performance of HFpEF probability scores (HFA-PEFF and H2FPEF) in patients with heart failure with prese…
Heart failure scores work well for typical cases but lose accuracy in patients with atrial fibrillation or obesity due to altered biological…